ad1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T41180	JQAD1		Epigenetic Reader Domain
	JQAD1 is a potent and selective histone acetyltransferase EP300 degrader (PROTAC®; DC50≤ 31.6 nM); comprises an EP300 inhibitor, A485, joined by a linker to a cereblon E3 ligase ligand. JQAD1 brings about degradation of ...		Epigenetic Reader Domain
T35329L	EAD1 TFA(1644388-26-0 Free base)	EAD1 HCL(1644388-26-0 Free base)	Apoptosis , Autophagy
	EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis		Apoptosis , Autophagy
T81885	Mad1 (6-21) (TFA)
	Mad1 (6-21) TFA, a fragment encompassing amino acids 6 to 21 of the Mad1 protein, exhibits a strong affinity for the PAH2 domain of mammalian Sin3A with a dissociation constant (Kd) of approximately 29 nM [1].
T83753	RAD17-derived Peptide TFA
	RAD17-derived peptide, a substrate for the ataxia-telangiectasia and RAD3-related protein/kinase (ATR), facilitates the identification of ATR inhibitors.
T35329	EAD1		Autophagy
	EAD1 is a useful organic compound for research related to life sciences. The catalog number is T35329 and the CAS number is 1644388-26-0.		Autophagy
T41012	Mad1 (6-21)	Mad1 (6-21)
	Mad1 (6-21) is a peptide fragment derived from the Mad1 protein, specifically encompassing residues 6 to 21. This fragment exhibits binding affinity towards the mammalian Sin3A PAH2 domain, with a Kd value of approximate...
T39531	RAD16-I hydrochloride	RAD16-I hydrochloride
	RAD16-I hydrochloride is a self-assembling peptide with nanofibrous morphology that provides an optimal microenvironment for the proliferation and differentiation of human mesenchymal stem cells (hMSC) into chondrocytes....
T78915	AD186		Sigma receptor
	AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for S1R and 27 nM for S2R. Notably, AD186 completely reverses the antiallodynic effect of BD-1063 [1].		Sigma receptor

Compounds

JQAD1

T41180

Synonym:

Target: Epigenetic Reader Domain

EAD1 TFA(1644388-26-0 Free base)

T35329L

Synonym: EAD1 HCL(1644388-26-0 Free base)

Target: Apoptosis, Autophagy

RAD17-derived Peptide TFA

RAD16-I hydrochloride

T39531

Synonym: RAD16-I hydrochloride

Target: Sigma receptor

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc)	Human	HEK293
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-03884	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-03885	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02110	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02221	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPH-02222	TEAD1 Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPH-01321	FLAD1 Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
TMPH-03060	NaD1 Protein, Nicotiana alata, Recombinant (His & SUMO)	Nicotiana alata	E. coli
	Plant defense peptide with antifungal activity against F.oxysporum and B.cinerea. Retards the growth of the Lepidopteran insect pests H.armigera and H.punctigera.
TMPH-01194	Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO)	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) is expressed in E. coli.
TMPJ-01129	SMAD1 Protein, Human, Recombinant (GST)	Human	E. coli
	SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcripti...
TMPH-01193	Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His)	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His) is expressed in E. coli.
TMPH-01192	Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain AD169) Large structural phosphoprotein (Avi & His & MBP), Biotinylated is expressed in E. coli.
TMPH-01190	Human cytomegalovirus (HCMV) (strain AD169) glycoprotein H/gH Protein (His & SUMO)	HHV-5	E. coli
	Human cytomegalovirus (HCMV) (strain AD169) glycoprotein H/gH Protein (His & SUMO) is expressed in E. coli.