TSH Receptor

The thyrotropin receptor (or TSH receptor) is a receptor (and associated protein) that responds to thyroid-stimulating hormone (also known as "thyrotropin") and stimulates the production of thyroxine (T4) and triiodothyronine (T3). The TSH receptor is a member of the G protein-coupled receptor superfamily of integral membrane proteins and is coupled to the Gs protein.

Cat. No.	Product name	CAS No.	Purity
T12073	ML-109	1186649-91-1	98.14%
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)
T13216	TSHR antagonist S37	1217616-61-9	98.35%
TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).
T12192	NCGC00229600	1338824-20-6	99.27%
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenous...
T5383	D3-βArr	662164-09-2	99.43%
D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T12073

ML-109

1186649-91-1

98.14%

ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)

T13216

TSHR antagonist S37

1217616-61-9

98.35%

TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).

T12192

NCGC00229600

1338824-20-6

99.27%

NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenous...

T5383

D3-βArr

662164-09-2

99.43%

D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.