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Monocarboxylate transporter

The monocarboxylate transporters, or MCTs, are a family of proton-linked plasma membrane transporters that carry molecules having one carboxylate group (monocarboxylates), such as lactate and pyruvate, across biological membranes.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T81962 Lactate transportor 1 98%
Lactate transportor 1
Lactate Transporter 1 (Compound 1) serves as an active lactate transporter within living cells and exerts cytotoxic effects, exhibiting IC50 values of 3.36 μM in...
T7460 α-Cyano-4-hydroxycinnamic acid 28166-41-8 99.8%
α-Cyano-4-hydroxycinnamic acid
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate tra...
T0693 Niflumic acid 4394-00-7 99.79%
Niflumic acid
Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.
T0689 D-Phenylalanine 673-06-3 99.77%
D-Phenylalanine
D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).
T3210 AZD3965 1448671-31-5 99.75%
AZD3965
AZD3965 (AZD-3965) is a selective inhibitor of monocarboxylate transporter 1 (MCT1).
T60165 VB124 2230186-18-0 99.21%
VB124
VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for ...
T5208 BAY-8002 724440-27-1 99.13%
BAY-8002
BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).
T67727 MCT1-IN-3 2878360-80-4 98.87%
MCT1-IN-3
MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor. The solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) represents a promising targ...
T14316 AR-C155858 496791-37-8 98.84%
AR-C155858
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
T64378 AZD0095 2750001-23-9 98.26%
AZD0095
AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.
T5845 7ACC1 50995-74-9 98%
7ACC1
7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx. This singular activity ...
T1768 7ACC2 1472624-85-3 100%
7ACC2
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.
Lactate transportor 1
T81962
Lactate Transporter 1 (Compound 1) serves as an active lactate transporter within living cells and exerts cytotoxic effects, exhibiting IC50 values of 3.36 μM in...
α-Cyano-4-hydroxycinnamic acid
T7460
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate tra...
Niflumic acid
T0693
Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.
D-Phenylalanine
T0689
D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).
AZD3965
T3210
AZD3965 (AZD-3965) is a selective inhibitor of monocarboxylate transporter 1 (MCT1).
VB124
T60165
VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for ...
BAY-8002
T5208
BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).
MCT1-IN-3
T67727
MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor. The solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) represents a promising targ...
AR-C155858
T14316
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
AZD0095
T64378
AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.
7ACC1
T5845
7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx. This singular activity ...
7ACC2
T1768
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.
TargetMol