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T0740 Metformin hydrochloride Metformin HCl, a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the proliferation of a variety of Y cells includi...
T0800 Antrapurol Danthron is a natural product, regulates glucose, and lipid metabolism by activating AMPK.
T1453 Phenformin hydrochloride Phenformin is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.
T1477 AICAR (Acadesine) Acadesine is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating oth...
T1977 Dorsomorphin Dorsomorphin is an effective and specific inhibitor of AMPK (AMP-activated protein kinase), which is induced by AICAR and metformin.
T2133 Adenosine 5'-monophosphate Adenosine 5'-monophosphate is an ester of phosphoric acid with the nucleoside adenosine.
T2374 HTH-01-015 HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM).
T2468 A 769662 A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).
T2854 Forsythin Phillyrin is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking the expres...
T2978 Mogroside V Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edem...
T2S0410 Euphorbia factor L1
T3676 Sesamol Sesamol could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upr...
T3863 Chikusetsusaponin IVa Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed int...
T3S0195 Nootkatone 1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent...
T4427 PF-06409577 PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).
T5187 MK-3903 MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).
T5497 AMAROGENTIN Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell...
T5576 YKL-06-061 YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.
T5993 ARN-3236 ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nM respectivel...
T6146 Dorsomorphin dihydrochloride Dorsomorphin is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T6291 WZ4003 WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 oth...
T7327 7-Methoxyisoflavone 7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK).
T7362 O-304 O-304 is a pan-activator of AMP-activated protein kinase (AMPK).
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