ysl

Tyroserleutide (YSL), a small molecular tripeptide isolated from porcine spleen degradation products, inhibits the growth and metastasis of human hepatocellular carcinoma (HCC) both in vitro and in vivo.

DSTYSLSSTLTLSK, a human peptide, facilitates the quantitative detection of Infliximab (Avakine), a chimeric monoclonal IgG1 antibody. Infliximab specifically targets and binds to TNF-α.

DSTYSLSSTLTLSK acetate is a human generic peptide that can be used for the quantitative detection of infliximab.

DSTYSLSSTLTLSK TFA, a generic human peptide, facilitates the quantitative detection of Infliximab (Avakine), a chimeric monoclonal IgG1 antibody targeting TNF-α, as indicated in study [1].

IRGRILHDGAYSLTLQGLGIH TFA, a multi-epitope class II rat HER2/neu peptide, is utilized in the study of class II HER2-DC1 vaccines [1].

IRGRILHDGAYSLTLQGLGIH is a multi-epitope class II rat HER2/neu peptide used in HER2-DC1 vaccine research studies [1].

Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.

Pentalysine is a peptide.

Amyloid β-Protein (36-42), the 36-42 fragment of β-Amyloid, consists of a polypeptide chain of 36-43 amino acids and is a primary constituent of amyloid plaques in Alzheimer's disease (AD) patients' brains. β-Amyloid oligomers (Aβos) critically contribute to AD progression by causing neuronal harm and cognitive decline [1].

H-Leu-Ser-Lys-Leu-OH (LSYL), a latency-associated peptide located at the amino terminus of LAP, inhibits TGF-β1 activation by binding with KRFK, thereby obstructing TGF-β1 signal transduction and inhibiting the progression of hepatic damage and fibrosis [1].

PA22-2 (free acid) (Cys-Laminin A chain 2091-2108), a peptide, promotes neurite outgrowth and facilitates the formation of neuron-like processes. It is used in the culturing of human adenoid cystic carcinoma cells and the development of peptide-functionalized supported phospholipid bilayers [1] [2] [3].

Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is a 13-mer synthetic peptide with a sequence homologous to seven amino acids of the SV40 T antigen, recognized for its ability to induce nuclear transport [1].

[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing mice with this peptide (50 µg) mixed in complete Freund's adjuvant (CFA) elevates IL-4 levels in the spleen. While it suppresses Th1 cell activation in vitro, it does not do so in vivo; instead, it promotes the development of regulatory T cells. Preimmunization with [Leu144, Arg147]-PLP (139-151) postpones the onset of experimental autoimmune encephalomyelitis (EAE) triggered by encephalitogenic peptides from PLP (178-191), myelin oligodendrocyte glycoprotein (MOG) (92-106), or myelin basic protein (MBP) in mice.

LSKL TFA (H-Leu-Ser-Lys-Leu-NH2 TFA) is a LAP-TGFβ derivative and a TGF-β1 antagonist that can cross the blood-brain barrier, inhibits the binding of TSP-1 to LAP and reduces renal interstitial fibrosis and liver fibrosis, inhibits subarachnoid fibrosis by inhibiting TSP-1-mediated TGF-β1 activity, prevents the occurrence of chronic hydrocephalus and improves long-term neurocognitive deficits after subarachnoid hemorrhage.

H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate acts as antioxidant by reacting with active oxygen species such as superoxide and hydroxyl radicals.

Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.

Cys-LT7 is a Cys-modified analog of the LT7 peptide. LT7 (HAIYPRH) is a homing peptide for the transferrin receptor (TfR) with a binding site distinct from that of transferrin (Tf). Cys-LT7 can be utilized in the development of drug delivery systems targeting the transferrin receptor (TfR).