scaffold — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8574	SPHINX		Others
	SPHINX is a new generation inhibitor of SPRK1		Others
T8116	Azulene	Bicyclo[5.3.0]Decapentaene	Others , HIV Protease
	Azulene (Bicyclo[5.3.0]Decapentaene) is a natural product.		Others , HIV Protease
T2253	TCS PIM-1 1	SC 204330	Pim
	TCS PIM-1 1 (SC 204330)(sc-204330) is a effective and specific ATP-competitive Pim-1 kianse inhibitor (IC50: 50 nM) , exhibits good specific over MEK1/MEK2 and Pim-2(IC50s >20, 000 nM).		Pim
T5901	3-Hydroxy-2-methylpyridine		Others
	3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.		Others
T8925	Glu-urea-Lys
	Glu-urea-Lys is a molecular scaffold that targets PSMA and can be used as a prostate cancer imaging agent to study prostate-specific membrane antigens.
T23146	PHA 568487 free base	PHA 568487	AChR
	The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...		AChR
T75098	HIF-PHD-IN-3		Reactive Oxygen Species
	HIF-PHD-IN-3 is a potent hiPSC-CM cardioprotective scaffold with potential inhibitory effects on HIF-PHD, regulates heme oxygenase-1, and can be used to study anaemia.		Reactive Oxygen Species
T4S1616	Sanggenon D	Sanggenone D	NOS , COX , GABA Receptor
	Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysa...		NOS , COX , GABA Receptor
T7962	Coumalic acid	Cumalic Acid	Others
	Coumalic acid (Cumalic Acid) can be prepared from malic acid. It can be used in the industrial production of spices, flavorings, and cosmetics. It serves as a polymer component as well as an active molecular scaffold wit...		Others
T23002	ML-335		Opioid Receptor
	ML-335 is a μ-δ isomer-targeted agonist, a μOR-δOR-biased ligand that can serve as a scaffold for the development of unique types of (isomer-biased) drugs.ML-335 is a MOR (μ-opioid receptor)/DOR (δ-opioid receptor) heter...		Opioid Receptor
T64374	QN523		Autophagy
	QN523 represents a novel scaffold with drug-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 shows significant in vivo efficacy in a pancreatic cancer xenograft model. Autop...		Autophagy
Fr13587	7-Chloro-4-(piperazin-1-yl)quinoline
	7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. It exhibited either alone or as hybrid with other active pharmacophores diverse pharmacological profiles. 7-Chloro-4-(piperazin-1-yl)q...
T40111L	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride		PD-1/PD-L1
	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi...		PD-1/PD-L1
TNU0121	5-Pyrrolidinomethyluridine
	5-Pyrrolidinomethyluridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Scaffold and Template.
TNU1278	2,6-Dichloro-2',3',5'-triacetyl-purine riboside
	2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template.
TNU0870	5-(2-Hydroxyethyl)uracil
	5-(2-Hydroxyethyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.
TNU0872	5-(3-Hydroxypropyl)uracil
	5-(3-Hydroxypropyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.
T68365	Indimitecan HCl
	Indimitecan HCl is a TOP1 inhibitor chemical scaffold.
TNU0275	8-Aza-7-bromo-7-deazaguanosine
	8-Aza-7-bromo-7-deazaguanosine is a Nucleoside Derivative - 7-Deaza-8-aza-purine nucleoside; Halo-nucleoside; Scaffold and Template.
T26183	Selenalysine
	Selenalysine is a lantipeptides used as a scaffold for drug development.