pyrazole

1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole dihydrochloride, with CAS No. 157327-47-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole dihydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha (ERα), exhibiting a relative binding affinity of 49% for ERα, which is approximately 410 times higher than its affinity for estrogen receptor beta (ERβ: 0.12%).

Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.

1H-Pyrazole, 4,5-dihydro-1,3,5-triphenyl- is a bioactive chemical.

(S)-2-((R)-3-(4-chlorophenyl)-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide is a cannabinoid receptor antagonist/inverse agonist.

Ethyl 1H-pyrazole-4-carboxylate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

1H-pyrazole (1,2-Diazole), is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic and antibacterial activities.

1,3-Dimethylpyrazole (2,5-Dimethylpyrazole) is a bioactive compound isolated from Moso Bamboo Root.

1-Methylpyrazole is a nitrogen-containing heterocyclic compound that can be used in biochemical experiments and drug synthesis research.

1,5-diphenylpyrazole-3-carboxylic acid (1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL-) is a plant-physiologically tolerable salt radical or any desired ester radical.

1,3,5-Trimethyl-1H-Pyrazole-4-Carboxylic Acid (1,3,5-trimethylpyrazole-4-carboxylic acid) is a marine derived natural products found in Cinachyrella sp.

3-Bromo-5-(trifluoromethyl)pyrazole is a pyrazole derivative applicable for biochemical experiments and drug synthesis research.

BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease.

Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor that distinguishes between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells (IC50: 0.72 μM) and has an IC50 of 13.08 μM for store-operated Ca2+ entry in BRL-2H3 cells.

yGsy2p-IN-1 is a potent inhibitor of yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1). Additionally, yGsy2p-IN-H23, a pyrazole inhibitor, is utilized in the treatment of glycogen storage diseases (GSDs).

ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through inhibition of the NF-κB signaling pathway, in the regulation of antioxidant response through activation of the Nrf2 signaling pathway, and in the regulation of cell survival and proliferation through inhibition of the Akt signaling pathway.

(S)-2-(1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1-(2-hydroxy-2-phenylethyl)-1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing the crucial amide benzimidazole (ABZI) component. It consistently inhibits the binding of 3 H-cGAMP to STING, with an apparent inhibition constant (IC50) of 14 μM. This compound is applicable in tumor research.

[1]Benzothiopyrano[4,3-c]pyrazole-3-carboxamide, n-[3-(4-cyclohexyl-1-piperazinyl)propyl]-1,4-dihydro-1-methyl- is a useful organic compound for research related to life sciences.

1-Methyl-1H-pyrazole-3-carbonitrile ,with CAS No. 79080-39-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Methyl-1H-pyrazole-3-carbonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-(Trifluoromethyl)pyrazole, with CAS No. 20154-03-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-(Trifluoromethyl)pyrazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1H-pyrazole, 3-(5-chloro-2-thienyl)-4,5-dihydro-1-methyl- ,with CAS No. 883019-49-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H-pyrazole, 3-(5-chloro-2-thienyl)-4,5-dihydro-1-methyl- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Methyl-3-(2-thienyl)-4,5-dihydro-1H-pyrazole dihydrochloride ,with CAS No. 1052407-05-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Methyl-3-(2-thienyl)-4,5-dihydro-1H-pyrazole dihydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Methyl-5-thiophen-2-yl-1H-pyrazole ,with CAS No. 59843-89-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Methyl-5-thiophen-2-yl-1H-pyrazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-(3-thienyl)-1H-pyrazole(SALTDATA: 0.7H2O), with CAS No. 19933-25-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-(3-thienyl)-1H-pyrazole(SALTDATA: 0.7H2O) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.