polysaccharide

Polysaccharide is a natural product that can be used in related research in the field of life sciences. Its product number is TN8891.

Astragalus polysaccharide, a natural product derived from Astragalus propinquus, exhibits anticancer activity and has been shown to be effective in hepatocellular carcinoma (HCC) by inhibiting the M2 polarization of tumor-associated macrophages (TAM).

Radix Astragali polysaccharide is a natural product that can be used in related research in the field of life sciences. Its product number is TN8876.

Polysaccharide of Salvia miltiorrhiza is a natural product that can be used in related research in the field of life sciences. Its product number is TN8882.

Polysaccharide of Atractylodes macrocephala is a natural product that can be used in related research in the field of life sciences. Its product number is TN8889.

Polysaccharide Chinese Angelica is a natural product that can be used in related research in the field of life sciences. Its product number is TN8896.

Dangshen polysaccharide is a natural product that can be used in related research in the field of life sciences. Its product number is TN8898.

Polysaccharide of Isatis tinctoria is a natural product that can be used in related research in the field of life sciences. Its product number is TN8904.

Polysaccharide of Hericium erinaceus is a natural product that can be used in related research in the field of life sciences. Its product number is TN8909.

Lipopolysaccharides (LPS), derived from Escherichia coli O55:B5, are essential components of the outer membrane of Gram-negative bacteria. Composed of lipid A, a core oligosaccharide, and an O-specific polysaccharide, LPS exhibits strong immunogenicity. It activates immune cells via the TLR4 receptor, induces chemotactic cell migration and cytokine secretion, and helps maintain the integrity of the bacterial outer membrane, protecting against bile salts and lipid-based antibiotics. LPS is commonly used to establish inflammatory models, including arthritis, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), and gastrointestinal disease models.

Lipopolysaccharides from Escherichia coli O111:B4 are key components of the outer membrane of Gram-negative bacteria. As a smooth-type LPS, they consist of lipid A, an R3-type core oligosaccharide, and an O-specific polysaccharide. These LPS molecules exhibit high immunogenicity, can trigger strong immune responses and gastric disorders by activating the TLR-4 receptor on immune cells, and help maintain the structural integrity of the bacterial outer membrane while protecting against bile salts and lipid-based antibiotics. They are widely used to establish inflammation-related disease models, such as chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS).

Rosa roxburghii Tratt polysaccharides is a natural product that can be used in related research in the field of life sciences. Its product number is TN8910.

Oldenlandia diffusa Polysaccharides is a natural product that can be used in related research in the field of life sciences. Its product number is TN8911.

Chitosan (MW 150000) (Deacetylated chitin) is a linear polysaccharide made up of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine.

Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid inhibits histamine release and can be used in the food industry.

Chitin is a large, structural polysaccharide found in the cell walls of fungi, the exoskeletons of insects, and certain hard structures in fish and invertebrates.

Amylose is a polysaccharide composed of α-D-glucose units linked by α(1→4) glycosidic bonds, accounting for about 20% of the total amount of starch. Amylose spatial conformation curls into a helix and forms a blue complex with iodine, which is widely used in the food industry, and can be used in a variety of researches as a natural product and a biochemical reagent.

Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and thymidine respectively), or deoxyribose-containing deoxynucleosides, and their corresponding ribonucleotides or deoxyribonucleotides. Pyrimidines serve essential functions in human metabolism as ribonucleotide bases in RNA (uracil and cytosine), and as deoxyribonucleotide bases in DNA (cytosine and thymine), and are linked by phosphodiester bridges to purine nucleotides in double-stranded DNA, in both the nucleus and the mitochondria. Pyrimidine activated sugars are also involved in polysaccharide and phospholipid synthesis, glucuronidation in detoxification processes, glycosylation of proteins and lipids and in the recently identified novel endothelium-derived vasoactive dinucleotides.

Addition of the Rhamnose (6-Deoxy-L-mannose)-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway, inducing fast and transient increases in Ca2 influx and intracellular free Ca2 level.

Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.

Heparan sulfate is a natural product, a linear polysaccharide. Heparan sulfate occurs as a proteoglycan (HSPG) that is tightly attached to cell surface or extracellular matrix proteins.

Gum Arabic, a branched-chain, complex polysaccharide derived from A. Senegal, exhibits antioxidant properties and offers protection against experimental hepatic, renal, and cardiac toxicities. Additionally, it finds application in immunohistochemistry.

Guar gum is a galactomannan polysaccharide extracted from guar beans, it has stabilizing and thickening properties useful in food, feed, and industrial applications.

L-Diguluronic acid, a linear polysaccharide copolymer consisting of two L-guluronic acid (G) units, serves as a precursor for Alginate[1], a categorically unbranched polyanionic polysaccharide. Alginate finds application in the development of antifungal agent delivery carriers[2].