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mineralocorticoid

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  • Inhibitors & Agonists
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Ecdysone
TN39103604-87-3
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death.
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Aldosterone
T1918652-39-1
Aldosterone, the primary mineralocorticoid, is synthesized and secreted by the zona glomerulosa of the adrenal cortex in response to activation of the renin-angiotensin system or high dietary potassium.
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7-10 days
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deoxycorticosterone
Desoxycortone, Desoxycorticosteronum, Desoxycorticosterone
T2030264-85-7
Deoxycorticosterone (Desoxycortone) is a steroid metabolite produced by the adrenal gland. Deoxycorticosterone is an aldosterone precursor and possesses mineralocorticoid activity.
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4-6 weeks
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Deoxycorticosterone acetate
DOC acetate, Cortexone acetate, 11-Deoxycorticosterone acetate
T303356-47-3
Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
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18-Oxocortisol
T399912410-60-8
18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.
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