Search Result

Search Results for " ligand-binding "

Targets

148

Compounds

Natural Products

563

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T13884	Shield-1		Others
	Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused protein...		Others
T13273	UT-34		Androgen Receptor
	UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prost...		Androgen Receptor
T7904	SR 19881		Estrogen/progestogen Receptor
	SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).		Estrogen/progestogen Receptor
T0214	Pioglitazone	U 72107	Ferroptosis , PPAR
	Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury.		Ferroptosis , PPAR
T8381	Amodiaquine		Others , Histone Methyltransferase , Parasite
	Amodiaquine is a synthetic aminoquinoline, used to treat malaria.		Others , Histone Methyltransferase , Parasite
T23151	Phortress	NSC 710305	AhR
	Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activity.		AhR
T9628	10074-A4		c-Myc
	10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.		c-Myc
T11399	Giredestrant	GDC-9545	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand,...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T7388	GSK805		ROR
	GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA bindi...		ROR
T24925	UNC-2170	UNC2170 Maleate,UNC-2170 Maleate,UNC 2170 Maleate	Others
	UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.		Others
T5160	SR3335	ML 176	ROR
	SR3335 (ML 176) is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM).		ROR
T23777	BCI-137	BCI137	Others
	BCI-137 is an Argonaute 2 ligand. It acts by targeting the MicroRNA Binding Domain.		Others
T13566	Bamirastine	TAK-427	Histamine Receptor
	Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect on allergic skin inflammation.		Histamine Receptor
T13848	SMARCA-BD ligand 1 for Protac		Epigenetic Reader Domain
	SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2		Epigenetic Reader Domain
T18787	TD-165		Others , Ligand for E3 Ligase
	TD-165, a PROTAC-based cereblon (CRBN) degrader, consists of a cereblon (CRBN) ligand-binding group, a linker, and a von Hippel-Landau (VHL) binding group[1].		Others , Ligand for E3 Ligase
T22051	BU 224 hydrochloride		Imidazoline Receptor
	BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.		Imidazoline Receptor
T18595	Dasatinib carbaldehyde	PROTAC ABL binding moiety 4,BMS-354825 carbaldehyde	Others , Ligands for Target Protein for PROTAC
	Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].		Others , Ligands for Target Protein for PROTAC
T8486	GW6471	GW 6471	PPAR
	GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.		PPAR
T9108	BI-0115		Lipoxygenase
	BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX...		Lipoxygenase
T16153	MS4078		ALK , Ligand for E3 Ligase
	MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.		ALK , Ligand for E3 Ligase
T14987	CMP8		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, res...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T8864	Thymidylate Kinase Inhibitor, YMU1		Others
	YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.		Others
T9435	1-(4-Carbethoxyphenyl)-piperazin		Others
	1-(4-Carbethoxyphenyl)-piperazin is used as a reagent for enzymes and chemical synthesis, as a model substrate for enzyme studies, and as a ligand for receptor binding assays.		Others
T4023	L-Argininamide dihydrochloride	H-Arg-NH2.2HCl	Others
	L-Argininamide dihydrochloride (H-Arg-NH2.2HCl) is used as a model compound in studies of the physicochemical characteristic of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.		Others
T73599	TSPO ligand-1		Autophagy
	TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autop...		Autophagy
T73475	SMN-C2		DNA/RNA Synthesis
	SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the...		DNA/RNA Synthesis
T15424	GSK1379725A		Epigenetic Reader Domain
	GSK1379725A is a selective BPTF ligand (Kd: 2.8 uM). It also shows no binding activity for Brd4.		Epigenetic Reader Domain
T5437	Gefitinib-based PROTAC 3		EGFR
	Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectivel...		EGFR
T8779	HBT1		GluR
	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate...		GluR
T18750	N-Deshydroxyethyl Dasatinib	N-Deshydroxyethyl BMS-354825	Others , IAP , Drug Metabolite
	N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER.N-Deshydroxyethyl Dasatinib i...		Others , IAP , Drug Metabolite
T15410	GNF351		Aryl Hydrocarbon Receptor
	GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes wit...		Aryl Hydrocarbon Receptor
T2086	ELN-441958	ELN 441958	Bradykinin Receptor
	ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors.		Bradykinin Receptor
T2194	Direct Blue 1	Pontamine sky blue,Chicago Sky Blue 6B	GluR
	Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacti...		GluR
T9542	NS3861		AChR
	NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and bind with high affinity to heteromeric α3β4 and α4β2 nAChRs. NS3861 displays the β-subunit preference and a complete lack of activation at α4-contain...		AChR
T17182	TX1-85-1		EGFR
	TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a cova...		EGFR
T77549	Nurr1 agonist 2		Others
	Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2). Nurr1...		Others
T8899	Metipranolol		Adrenergic Receptor
	Metipranolol (Betamann) is a type of β- Adrenergic receptors（ β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta bloc...		Adrenergic Receptor
T3716	Rolapitant	SCH619734	Neurokinin receptor
	Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ...		Neurokinin receptor
T3157	COH29	RNR Inhibitor COH29	DNA/RNA Synthesis
	COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...		DNA/RNA Synthesis
T77520	AOH1996		Apoptosis , DNA/RNA Synthesis
	AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its ...		Apoptosis , DNA/RNA Synthesis
T23254	RS 16566 dihydrochloride		Others
	ligand for the (R)-zacopride binding site		Others
T39440	CXCL12 ligand 1
	CXCL12 ligand 1 is the first ligand of the sY12-binding pocket on chemokine CXCL12 .
T24973	2-Iodoestradiol	2 Iodoestradiol,NSC671618,NSC 671618,NSC-671618
	2-Iodoestradiol is an effective human sex hormone-binding globulin (SHBG) ligand.
T17873	(4R,5S)-nutlin carboxylic acid	E3 ligase Ligand 15,MDM2 ligand 2	Others
	(4R,5S)-Nutlin Carboxylic Acid (MDM2 Ligand 2), a Nutlin 3-based MDM2 ligand, can be conjugated to a protein-binding ligand via a linker to create PROTACs[1].		Others
T23754	Argininamide	L-Arginamide,L-Argininamide,L-Arginine amide
	Argininamide is used in studies of the physicochemical characteristic of ligand binding DNA aptamers.
T13841	PROTAC Her3-binding moiety 1		Others
	PROTAC Her3-binding moiety 1 is a Her3 Ligand for PROTAC.		Others
T25577	Khusimol
	Khusimol is a vasopressin V1a receptors non-peptide ligand that acts by inhibiting the binding of vasopressin.
T27878	LY 164929	LY-164929,LY164929
	LY 164929 is a highly selective ligand for the lower affinity [3H]D-Ala2-D-Leu-5-enkephalin binding site.
T18599	PROTAC BRD4-binding moiety 1		Others
	PROTAC BRD4-binding moiety 1 is a BRD4 ligand that binds to the cereblon ligand through a linker, enabling the formation of a PROTAC complex. This complex efficiently degrades BRD4[1].		Others
T18610	PROTAC FKBP Degrader-3		Others
	PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].		Others

Compounds

Target: Androgen Receptor

SR 19881

T7904

Synonym:

Target: Estrogen/progestogen Receptor

Pioglitazone

T0214

Synonym: U 72107

Target: Ferroptosis, PPAR

Amodiaquine

T8381

Synonym:

Target: Others, Histone Methyltransferase, Parasite

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Synonym: UNC2170 Maleate,UNC-2170 Maleate,UNC 2170 Maleate

Target: Histamine Receptor

SMARCA-BD ligand 1 for Protac

T13848

Synonym:

Target: Epigenetic Reader Domain

TD-165

T18787

Synonym:

Target: Others, Ligand for E3 Ligase

BU 224 hydrochloride

T22051

Synonym:

Target: Imidazoline Receptor

Dasatinib carbaldehyde

T18595

Synonym: PROTAC ABL binding moiety 4,BMS-354825 carbaldehyde

Target: Others, Ligands for Target Protein for PROTAC

Target: ALK, Ligand for E3 Ligase

CMP8

T14987

Synonym:

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Thymidylate Kinase Inhibitor, YMU1

T8864

Synonym:

Target: Others

1-(4-Carbethoxyphenyl)-piperazin

T9435

Synonym:

Target: Others

L-Argininamide dihydrochloride

T4023

Synonym: H-Arg-NH2.2HCl

Target: DNA/RNA Synthesis

GSK1379725A

T15424

Synonym:

Target: Epigenetic Reader Domain

Gefitinib-based PROTAC 3

N-Deshydroxyethyl Dasatinib

T18750

Synonym: N-Deshydroxyethyl BMS-354825

Target: Others, IAP, Drug Metabolite

GNF351

T15410

Synonym:

Target: Aryl Hydrocarbon Receptor

ELN-441958

T2086

Synonym: ELN 441958

Target: Bradykinin Receptor

Direct Blue 1

T2194

Synonym: Pontamine sky blue,Chicago Sky Blue 6B

Target: Adrenergic Receptor

Rolapitant

T3716

Synonym: SCH619734

Target: Neurokinin receptor

COH29

T3157

Synonym: RNR Inhibitor COH29

Target: DNA/RNA Synthesis

AOH1996

T77520

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

RS 16566 dihydrochloride

Synonym: 2 Iodoestradiol,NSC671618,NSC 671618,NSC-671618

Target:

(4R,5S)-nutlin carboxylic acid

T17873

Synonym: E3 ligase Ligand 15,MDM2 ligand 2

Target: Others

Argininamide

T23754

Synonym: L-Arginamide,L-Argininamide,L-Arginine amide

Target:

PROTAC Her3-binding moiety 1

Synonym: LY-164929,LY164929

Target:

PROTAC BRD4-binding moiety 1

T18599

Synonym:

Target: Others

PROTAC FKBP Degrader-3

T18610

Synonym:

Target: Others

Cat No.	Product Name	Synonyms	Targets
T3806	Kaempferide	Kaempferol 4'-O-methyl ether,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Influenza Virus , Antibacterial , Autophagy
	kaempferide (4'-Methylkaempferol) inhibits the proliferation of native and estrogen receptor beta overexpressing colon cancer cells through a mechanism not mediated by ligand binding dependent estrogen receptor activatio...
TJS1183	Cyclen	1,4,7,10-tetraazacyclododecane	Others
	Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.		Others
TN3539	Broussonin A		ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt
	Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-lucife...		ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt

Natural Products

kaempferide

T3806

Synonym: Kaempferol 4'-O-methyl ether,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Influenza Virus, Antibacterial, Autophagy

Cyclen

TJS1183

Synonym: 1,4,7,10-tetraazacyclododecane

Target: ERK, IL Receptor, IκB/IKK, NOS, NF-κB, Akt

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00131	NKG2DL Protein, Human, Recombinant (hFc)	Human	Human Cells
	NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC ...
TMPJ-00831	CCL3 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, ...
TMPY-05239	HER2/ERBB2 Protein, Human, Recombinant , Biotinylated	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-04698	HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His)	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-03719	HER2/ERBB2 Protein, Canine, Recombinant (His)	Canine	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-05081	Notch 1 Protein, Human, Recombinant (hFc)	Human	HEK293
	NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair...
TMPY-01137	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01944	HER2/ERBB2 Protein, Rat, Recombinant (His)	Rat	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-02469	HER2/ERBB2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00636	HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-04684	HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-02314	HER2/ERBB2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00167	HER2/ERBB2 Protein, Human, Recombinant	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-05592	ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated	Human	HEK293
	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPJ-01430	NovoNectin Protein, Human, Recombinant	Human	E. coli
	Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containin...
TMPY-02333	ULBP-2 Protein, Human, Recombinant (His)	Human	HEK293
	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-01151	IFNGR1 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)	Human	HEK293
	Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine recept...
TMPY-02355	IFNGR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)	Human	Human Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ...
TMPY-01578	CD166/ALCAM Protein, Human, Recombinant (His)	Human	HEK293
	Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocyt...
TMPY-05376	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-05504	4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated	Rhesus	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-05767	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-01743	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-05594	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-01458	GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His)	Human	HEK293
	Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF...
TMPY-01168	ALK-1 Protein, Human, Recombinant (His)	Human	HEK293
	Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-01037	CSF1R Protein (Met1-Glu512), Human, Recombinant (His)	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPY-04805	Siglec-3/CD33 Protein, Human, Recombinant	Human	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-05016	HHLA2 Protein, Human, Recombinant (His)	Human	HEK293
	B7H7 gene encodes a protein-ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these ...
TMPY-02409	Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-03805	Siglec-3/CD33 Protein, Human, Recombinant (His)	Human	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-04952	Siglec-3/CD33 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-02304	Siglec-3/CD33 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-03102	IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-02676	EGFR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04818	EGFR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00742	EGFR Protein, Human, Recombinant (His)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-00137	APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)	Human	Human Cells
	APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPY-01446	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant	Mouse,Rat	Human Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPY-02034	Siglec-2/CD22 Protein, Human, Recombinant (His)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-00716	CD89 Protein, Human, Recombinant (His)	Human	HEK293
	FCAR, also called FcαRI or CD89, is a type I transmembrane receptor for Fc region of IgA which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. This recep...
TMPY-04083	Siglec-2/CD22 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05566	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05201	Siglec-2/CD22 Protein, Human, Recombinant	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-04976	PDGFC Protein, Mouse, Recombinant (His)	Mouse	Yeast
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
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