licorice

Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.

Licorice glycoside C2, an oleanane-type triterpene oligoglycoside, is isolated from [Glycyrrhiza uralensis].

24-Hydroxy-licorice-saponin A3, an oleanane-type triterpene saponin (OTS), can be isolated from Glycyrrhiza uralensis [1].

Licorice-saponin H2 (Licoricesaponin H2) is a natural product

Licorice-saponin H2 ammonium (compound 7) is a triterpene oligoglycoside from the oleanane group, which can be isolated from licorice roots.

Licoricesaponin A3 is a terpenoid saponin extracted from Gymnostachyum febrifugum Benth., which has good affinity for 5-LOX receptors.

Licoricesaponin G2, a pentacyclic triterpenoid derived from Glycyrrhiza aspera, can be used to differentiate crude liquorice from honey-processed liquorice.

Licoricesaponin E2 displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 umol/L, it could significantly increase the cytotoxic activity after hydrolysis.

Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, the main and sweet component of licorice, has been studied for its ability to cause hypermineralocorticoidism with potassium loss and sodium retention, edema, increased blood pressure, as well as inhibited the renin-angiotensin-aldosterone system.

Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.

Liquiritigenin (4',7-Dihydroxyflavanone), a flavonoid aglycone from licorice, is a highly selective estrogen receptor β (ERβ) agonist.

Echinatin (Retrochalcone) is extracted from licorice and is a natural chalcone. Echinatin has a wide range of biological activities including hepatoprotective, anti-inflammatory, anti-bacterial infections, and attenuates lung damage.

Methyl Glycyrrhizate is a compound derived from licorice and is used as a flavoring agent. Commonly used in cosmetics.

Licofuranocoumarin is a minor flavonoid extracted from Glycyrrhiza uralensis (licorice).

Glyurallin B, a flavonoid derived from Glycyrrhiza inflata and Glycyrrhiza uralensis (licorice), exhibits ABTS+ radical scavenging activity and lipid peroxidation inhibition, with EC50 values of 11.9 ± 0.58 μM and 15.3 ± 1.26 μM, respectively [1].

Glycyrrhizin-6'-methylester, a naturally occurring compound, is isolatable from Glycyrrhiza glabra, commonly known as licorice [1].

Glycyrrhizin-6''-methylester (compound 22), isolated from licorice root, functions as an aglycone to form methyl glucuronate, imparting a sweet, licorice flavor without bitterness. The free carboxyl group on the cone-bound glucuronic acid moiety is critical in contributing to the compound's natural sweetness and licorice taste [1].

Glycyrrhizin-6′,6′′-dimethylester (compound 23), an aglycone derived from licorice saponin isolated from licorice root, contributes to the production of methyl glucuronate, yielding comparable sweetness, licorice flavor, and bitterness [1].

3,4-Didehydroglabridin, a compound sourced from licorice, demonstrates protective effects against carbon tetrachloride-induced injury in HepG2 cells, presenting research potential for liver injury therapeutics [1] [2].

Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.

Licoflavonol is a flavonoid compound that can be extracted from licorice. It is an inhibitor of Salmonella Typhimurium serotype 3 secretion system and suppresses the secretion of Abeta by inhibiting β-site APP cleaving enzyme 1 (BACE1) transcription.

Licoisoflavanone is a natural product from Licorice.

Magnesium isoglycyrrhizinate hydrate (18α-Glycyrrhizic acid Magnesium hydrate) is an active ingredient derived from licorice with anti-inflammatory properties. It lowers alanine and aspartate aminotransferase activities and can be used in HIV-1 infection research.

2-(2-Hydroxy-5-methoxyphenoxy)-acrylic acid is a metabolite isolated from the endophytic fungus Phoma macrostoma, residing in the internal tissues of the medicinal plant Glycyrrhiza glabra (licorice).