impurity

Impurity B of Calcitriol is an impurity of Calcitriol. Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

Sofosbuvir impurity H, a diastereoisomer of Sofosbuvir (PSI-7977), is an impurity of Sofosbuvir, which is an HCV RNA replication inhibitor with potent anti-hepatitis C virus activity.

Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.

Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.

Calcipotriol Impurity C is an impurity of Calcipotriol, a ligand for VDR-like receptors.

Impurity of Doxercalciferol is an impurity of doxercalciferol, a synthetic analog of ergocalciferol used as a drug for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis.

Losartan potassium impurity E is a compound of Valsartan impurity.

Loratadine specified impurity F is a fluorinated analog of Loratadine.

Amlodipine besilate impurity G is a Calcium Channel antagonist with potential application in the study of neurological diseases and is an impurity in the synthesis of Amlodipine besilate.

Amlodipine besilate impurity D is a biochemical.

Amlodipine besilate impurity E is a biochemical.

Amlodipine besilate impurity B is a biochemical.

2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol, (RS, Z)- is a bioactive chemical.

Amlodipine besilate impurity F, also known as Amlodipine Dimethyl Ester, is a biochemical.

NMP-ACA (Cefepime impurity) is a useful organic compound for research related to life sciences.

Afatinib impurity 11 is a byproduct of Afatinib, an irreversible EGFR family inhibitor with IC50 values of 0.5 nM, 0.4 nM, 10 nM, and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M, and HER2, respectively[1].

Olmesartan medoxomil impurity C is an impurity of Olmesartan medoxomil, a potent and selective angiotensin (AT1 receptor) inhibitor with an IC50 of 66.2 μM.

Ciprofibrate impurity A is an impurity of Ciprofibrate, a PPARα agonist[1].

Cetirizine Impurity C, an impurity of Cetirizine, is related to the carboxylated metabolite of hydroxyzine. Cetirizine is a second-generation antihistamine acting as a specific, orally active, and long-acting antagonist of the histamine H1-receptor[1][2].

Mesalamine impurity P is an impurity of Mesalamine. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB [1].

Edoxaban impurity 4, an impurity of Edoxaban (DU-176), is a selective, potent, and orally active inhibitor of factor Xa (FXa), exhibiting Kis of 0.561 nM for free FXa and 2.98 nM for prothrombinase. As an anticoagulant agent, Edoxaban is utilized for stroke prevention[1][2].

Ibuprofen impurity 1 is a known impurity of Ibuprofen, an anti-inflammatory inhibitor that targets COX-1 and COX-2 with IC50 values of 13 μM and 370 μM, respectively[1].

Remdesivir O-desphosphate acetonide impurity is a contaminant found in Remdesivir (GS-5734), a nucleoside analogue recognized for its potent antiviral properties, particularly inhibiting SARS-CoV-2 (COVID-19) infection in vitro.