d 13

Guanosine-d13 is the deuterated form of Guanosine. Guanosine (DL-Guanosine) is a type of nucleoside composed of guanine linked to a ribose ring through a β-N9-glycosidic bond. It exhibits activity against HSV (herpes simplex virus).

MES-d13 is the deuterated form of MES. MES (2-Morpholinoethanesulphonic acid) serves as a zwitterionic buffer with an effective buffering range of pH 5.5-7.0. As a Good's buffer, MES is extensively used in biochemistry and molecular biology experiments, including cell culture, enzyme activity assays, electrophoresis, and protein research.

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13 is the deuterated variant of 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a lipid utilized in liposome synthesis and serves as a lipid component in lipid nanoparticle (LNP) systems.

Choline-d13(chloride) is a deuterated form of Choline chloride. Choline chloride, an organic compound and a quaternary ammonium salt, acts as both a substrate for acyl receptors and choline acetyltransferase. It serves as a photosynthesis enhancer in plants and is also used as a feed additive for poultry and livestock to boost egg and offspring production.

Thymol-d13 is the deuterated analog of Thymol. Thymol is a major monoterpenol found in essential oils derived from plants belonging to the Lamiaceae family, as well as other families such as Verbenaceae, Scrophulariaceae, and Ranunculaceae. It exhibits antioxidant, anti-inflammatory, antibacterial, and antifungal properties.

Palmitoleic acid-d13 is the deuterated form of Palmitoleic acid. Palmitoleic acid, a component of fatty acids, has the potential to prevent death from cerebrovascular diseases in SHRSP rats.

Acetylcholine-d13(bromide) is the deuterated form of Acetylcholine bromide.

Adenosine-d13 (Adenine riboside-d13; D-Adenosine-d13) is a deuterium-labeled form of Adenosine. Adenosine (Adenine riboside) is a widely present endogenous secretion that exerts effects via four G-protein-coupled receptors (A1, A2A, A2B, and A3). It influences nearly all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is a deuterium-labeled form of 2'-Deoxyguanosine (Deoxyguanosine), also known as guanine deoxyriboside.

D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection. |1. Lazzarini, C., Haranahalli, K., Rieger, R., et al. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrob. Agents Chemother. 62(5), e00156-00118 (2018).

The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor.

Colfosceril miristate-d13 (DMPC-d13) is the deuterated form of Colfosceril miristate. Colfosceril miristate (DMPC) is a synthetic phospholipid utilized in the study of liposomes and lipid bilayers. It is employed for research on lipid monolayers and bilayers.

Choline-d13 Bromide (N,N,N-trimethyl-d9; 1,1,2,2-d4) is a deuterated compound of Choline Bromide. Choline Bromide has a CAS number of 1927-06-6.

Pantothenic acid-13C3,15N (hemicalcium) is a version of D-Pantothenic acid labeled with 13C and 15N isotopes. D-Pantothenic acid is an essential micronutrient, serving as a precursor to coenzyme A (CoA). It plays a crucial role in numerous biological processes, including the regulation of carbohydrate, lipid, protein, and nucleic acid metabolism.

L-Glutamic acid-13C5,15N,d5 is an L-Glutamic acid labeled with 13C, 15N isotopes and deuterium. Acting as an excitatory amino acid neurotransmitter, L-Glutamic acid is an agonist for all subtypes of glutamate receptors, including metabotropic, NMDA, and AMPA receptors, and it stimulates the release of dopamine (DA) from dopaminergic nerve terminals.

Pyruvic acid-13C,d4 is the deuterated form of 13C-labeled pyruvic acid. It acts as an intermediate metabolite in the metabolic pathways of carbohydrates, proteins, and fats.

Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) is an isotopically labeled form of Oseltamivir acid, marked with 13C and deuterium. It serves as the active metabolite of Oseltamivir phosphate and functions by inhibiting influenza virus neuraminidase with an IC50 of 2 nM. This compound is orally active and applicable in the study of influenza virus A/B infections.

Mycophenolic acid-13C-d3 the 13C and deuterated compound of Mycophenolic acid. Mycophenolic acid has a CAS number of 24280-93-1. Mycophenolic acid is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Lusutrombopag-d13 is a deuterated compound of Lusutrombopag. Lusutrombopag has a CAS number of 1110766-97-6. Lusutrombopag is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.

Homovanillic Acid-13C-d3 the 13C and deuterated compound of Homovanillic Acid. Homovanillic Acid has a CAS number of 306-08-1. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

Levomefolic Acid-13C-d3 the 13C and deuterated compound of Levomefolic Acid. Levomefolic Acid has a CAS number of 31690-09-2. Levomefolinic acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. Levomefolinic acid is used as a treatment and to prevent Folate Deficiency

Alachlo-d13 (2,6-diethylphenyl-d13) is a deuterated compound of Alachlo.

Pantothenic Acid-13C3,15N Hemicalcium Salt (Standard) is a reference standard of Pantothenic Acid-13C3,15N Hemicalcium Salt intended for quantitative analysis, quality control, and related biochemical research applications.

β-Apo-13-carotenone D3 is the deuterium labeled β-Apo-13-carotenone. β-Apo-13-carotenone is an antagonist of RXRα.