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Results for "

cyclooxygenase

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    302
    TargetMol | Inhibitors_Agonists
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
  • Natural Products
    94
    TargetMol | Natural_Products
  • Recombinant Protein
    1
    TargetMol | Recombinant_Protein
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    5
    TargetMol | Isotope_Products
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    TargetMol | Antibody_Products
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    4
    TargetMol | Disease_Modeling_Products
Rutaecarpine
Rutecarpine, Rutacarpine, Rhetine
T297284-26-4
Rutaecarpine (Rhetine) is an inhibitor of COX-2 with IC50 of 0.28 μM.
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Ginsenoside C-K
Ginsenoside K, Ginsenoside compound K
T381139262-14-1
Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.
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TargetMol | Citations Cited
Acetaminophen
Paracetamol, APAP, 4'-Hydroxyacetanilide, 4-Acetamidophenol
T0065103-90-2
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7 25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.
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Ginsenoside Rd
Sanchinoside Rd, Panaxoside Rd, Gypenoside VIII
T287852705-93-8
Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.
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beta-Amyrone
β-Amyron
TN3500638-97-1
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.
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anemarsaponin B
T7030139051-27-7
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit platelet aggregation in vitro.
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[8]-Shogaol
8-SHOGAOL
T543036700-45-5
[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.
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Gnetol
T705286361-55-9
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. It is active in the inhibition of a
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Madecassic acid
L-Fucose, L-fucopyranose, Brahmic acid, 6-Deoxy-L-Galactose
T275818449-41-7
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.
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Xanthohumol
T33426754-58-1
Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows chemopreventive effects.
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20(S)-Ginsenoside Rg3
S-Ginsenoside Rg3, Rg3, Ginsenoside Rg3, 20S-Ginsenoside Rg3, 20(S)-Ginsenoside-Rg3
T340214197-60-5
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial cells(HUVEC) and has anti-angiogenesis activities.
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TargetMol | Citations Cited
Asaraldehyde
Asarylaldehyde, 2,4,5-trimethoxy-Benzaldehyde, Asaronaldehyde
T28264460-86-0
Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde), a natural COX-2 inhibitor, exhibits 17-fold selectivity than COX-1.
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Guaiacol
O-methylcatechol, 2-hydroxyanisole, o-methoxyphenol, 2-Methoxyphenol
T130190-05-1
Guaiacol (2-Methoxyphenol) is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator in chemical reactions that produce oxygen. When oxygen binds to it, the complex turns yellowish brown and absorbs light maximally at about 470 nm.
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(-)-Catechin
(-)-Catechuic acid, (-)-Cianidanol
T1359718829-70-4
(-)-Catechin ((-)-Cianidanol), an isomer of catechin, inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
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7-10 days
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Methyl salicylate
Wintergreen oil, Natural wintergreen oil, Methyl 2-hydroxybenzoate, Gaultheria oil, Betula oil, 2-Carbomethoxyphenol
T0399119-36-8
Methyl salicylate (Gaultheria oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments.
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Veratric acid
Veratrumenoic acid, 3,4-Dimethoxybenzoic acid
T374493-07-2
Veratric acid (3,4-Dimethoxybenzoic acid) is a benzoic acid derivative from plants and fruits, possessing antioxidant, anti-inflammatory, and blood pressure-lowering properties.
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(+)-Catechin Hydrate
T2778225937-10-0
(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems.
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Paradol
6-paradol, [6]-Gingerone
T711327113-22-0
Paradol ([6]-Gingerone) is a pungent phenolic substance found in ginger and other Zingiberaceae plants, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities,neuroprotective Effects.
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7-10 days
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Lornoxicam
Ro 13-9297, Chlortenoxicam, TS110
T146870374-39-9
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
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Salicylic acid
2-Hydroxybenzoic acid
T064969-72-7
Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
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Sodium salicylate
Salicylic acid sodium salt, 2-Hydroxybenzoic acid sodium salt
T033554-21-7
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
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Catechin
D-Catechin, Cianidanol, Catechuic acid, Catechinic acid, (+)-Catechin
T0822154-23-4
Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.
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(-)-Epicatechin gallate
Epicatechin gallate, ECG, (−)-Epicatechin 3-gallate, (-)-Epicatechin 3-O-gallate, (-)-Epicatechin 3-gallate
T27321257-08-5
(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.
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syringaldehyde
Syringic aldehyde, Springaldehyde
T3747134-96-3
syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg mL. Anti-hyperglycemic and anti-inflammatory activities.
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