c16

PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability. PAF (C16) (PAF (C16)) is a platelet-activating factor, a phospholipid-derived mediator and a ligand for PAF G protein-coupled receptor (PAFR). PAF (C16) has shown anti-apoptotic and anti-inflammatory activity in vitro, inhibiting Caspase-dependent apoptosis by interacting with its receptor (PAF-R) to perform cell signaling.

C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) ammonium, a member of the ganglioside family, features a saturated C16:0 acyl chain. It serves as a functional receptor for the cholera toxin B subunit, although it exhibits lower efficiency in endocytic and retrograde transport pathways. C16 Ganglioside GM1 (d18:1/16:0) ammonium is applicable in diarrhea disease research.

C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity.

13C C16 Sphingomyelin (D18:1/16:0) is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin by GC- or LC-MS. C16 Sphingomyelin is a form of sphingomyelin containing palmitate (16:0) at the variable acylation position. It is the most common form of sphingomyelin found in eggs and is less abundant in the brain and in milk. C16 Sphingomyelin interacts with cholesterol in ordered lipid domains (lipid rafts). Sphingomyelinases remove phosphorylcholine from C16 sphingomyelin to produce C16 ceramide. While ceramides commonly induce apoptosis, ceramides with different fatty acid chain lengths might direct distinct functions and, in some cases, reduce apoptosis.

C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. C16 globotriaosylceramide is also upregulated in plasma of patients with ovarian carcinoma compared to those with benign ovarian tumors or uterine fibroids.

C16 3'-sulfo galactosylceramide (d18:1/16:0) is a sulfated glycolipid. C16 3'-sulfo galactosylceramide (d18:1/16:0) is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice. C16 3'-sulfo galactosylceramide (d18:1/16:0) is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice. C16 3'-sulfo galactosylceramide (d18:1/16:0) is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice. C16 3'-sulfo galactosylceramide (d18:1/16:0) inhibits retinal ganglion cell growth in vitro. C16 3'-sulfo galactosylceramide (d18:1/16:0) has been used as an internal standard for quantifying C16 3'-sulfo galactosylceramide (d18:1/16:0) in rat cerebellum and white matter isolated from patients with multiple sclerosis. reference for sulphides.

GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.

C16 1-Deoxyceramide (m18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 1-Deoxyceramide (m18:1/16:0) is 1246298-56-5.

C16 Ceramide-1-phosphate (d18:1/16:0) ammonium salt (C16 C1P ammonium salt) is an ester product used in synthesizing nanobiomaterials.

C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is 890041-50-6.

C16 PEG750 Ceramide (C16 PEG Ceramide (MW 750)) is a PEG lipid used in the preparation of liposomes, applicable in drug delivery research.

C16 Ceramide-D7 (Standard) is a reference standard of C16 Ceramide-D7 intended for quantitative analysis, quality control, and related biochemical research applications. C16 Ceramide-d7 is a deuterated compound of C16 Ceramide.

Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a platelet-activating factor analogue with PAF agonist properties, activating inflammation in pregnancy tissues and promoting preterm birth.

Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.

Amino-PEG6-amido-C16-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Amino-PEG6-amido-C16-COOH, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].

Amino-PEG9-amido-C16-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker used in PROTAC synthesis[1].

Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker used in PROTAC synthesis [1].

Boc-C16-NHS ester, an alkyl/ether-based PROTAC linker, enables the synthesis of PROTACs[1].

C16 dihydro Ceramide (d18:0/16:0) (Cer(d18:0/16:0)) is a precursor for the synthesis of ceramides, induces autophagy in the perinuclear region, and can be used to study cell membrane stability and neurological diseases.

C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.

C16-Urea-Ceramide s a neutral ceramidase (nCDase) inhibitor. It is a bioactive ceramide.