Home Tools
Log in
Products Inhibitors Libraries Recombinant Proteins Kits Services Contact Us
Cart
Peptides Monoclonal Antibodies Dye Reagents PROTAC Virtual Screening TargetMol Kits Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails Natural Products Phenols Alkaloids Flavonoids
Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " butyrylcholinesterase "

Targets

AChE

53

Compounds

27

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T0229 Rivastigmine SDZ-ENA 713,S-Rivastigmine,Exelon AChE
Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
T1628 Rivastigmine tartrate SDZ-ENA 713,ENA 713 AChR , AChE
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON...
T23131 PE 154 AChE
PE 154 is a potent fluorescent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 280 pM and 16 nM respectively. PE 154 is commonly used to label β-amyloid plaques in histochemical an...
T10630 BuChE-IN-TM-10 TM-10 AChR
BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE), exhibiting an IC50 of 8.9 nM. It effectively inhibits and disaggregates self-induced Aβ aggregation, displays significant antioxidant activit...
T21393 Ethopropazine Hydrochloride Lysivane,Parphezein,Dibutil,Parfezin,Profenamine HCl,Pardisol
Ethoproprazine hydrochloride is an butyrylcholinesterase inhibitor. It reduces extrapyramidal motor effects and used as an antidyskinetic, characteristic of Parkinson′s disease. It also alleviates thermal hyperalgesia in...
T16814 RX 67668 Others
RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue. RX 67668 is an effective cholinesterase inhibitor (IC50: 5 μM for both acetylcholinesterase and butyrylcholinesterase). RX 67668 can reverse the neur...
T73187 BuChE-IN-7
BuChE-IN-7 is a selective inhibitor targeting human butyrylcholinesterase (hBuChE) and equine butyrylcholinesterase (eqBuChE), demonstrating IC50 values of 40 nM and 80 nM, respectively. Demonstrating the ability to pene...
T26827 Bisnorcymserine N1 N8 Bisnorcymserine,N1N8Bisnorcymserine,N1-N8-Bisnorcymserine
Bisnorcymserine is a reversible inhibitor of butyrylcholinesterase. The leaving group, bisnoreseroline, interacts in a non-covalent way with Ser(200) and His(440), disrupting the existing interactions within the catalyti...
T38740 Rivastigmine carbamate impurity 3-Nitrophenyl ethyl(methyl)carbamate
Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is a byproduct found in Rivastigmine, which is recognized as a powerful and orally active inhibitor of cholinesterase (ChE). Specifically, Rivastigmi...
T73184 BChE-IN-15
BChE-IN-15 is a compound characterized as a pseudo-irreversible, covalent inhibitor of butyrylcholinesterase (BChE), demonstrating potent activity with an inhibitory concentration (IC50) of 1.76 nM against human BChE (hB...
T61669 BChE-IN-4
BChE-IN-4 is a highly potent inhibitor of the enzyme butyrylcholinesterase, capable of crossing the blood-brain barrier. It effectively reduces learning and memory impairments resulting from a deficiency in cholinergic a...
T61399 Z164597606
Z164597606 is a compound that acts as a selective inhibitor of the enzyme Butyrylcholinesterase (BChE), with IC50 values of 1.3 μM and 1.7 μM for equine BChE and human BChE, respectively. Through a π-π stacking interacti...
T75145 TRV-7019
TRV-7019 is a butyrylcholinesterase-targeting radioligand capable of penetrating the blood-brain barrier (BBB) for brain imaging. It is utilized for diagnosing conditions such as amyloid diseases, multiple sclerosis, bra...
T70607 Cymserine
Cymserine is a drug related to physostigmine, which acts as a reversible cholinesterase inhibitor, with moderate selectivity for the plasma cholinesterase enzyme butyrylcholinesterase, and relatively weaker inhibition of...
T69495 Affinisine
Affinisine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana. It may be an effective inhibitor of both acetylcholinesterase and butyrylcholinesterase based on previous rese...
T30876 CHF 2819 Ganstigmine HCl,CHF-2819,Ganstigmine hydrochloride,CHF2819
CHF 2819 is a novel orally active acetylcholinesterase inhibitor (AChE) developed for the treatment of Alzheimer's disease (AD). CHF 2819 is a selective inhibitor of AChE, it is 115 times more potent against this enzyme ...
T79422 BuChE-IN-8
BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) and Aβ40 aggregation. It also demonstrates notable antiamnesic pr...
T62336 BChE-IN-3
BChE-IN-3 is a selective, selective, time-dependent, pseudo-irreversible inhibitor of BChE butyrylcholinesterase (IC50: 56.9 nM).BChE-IN-3 exhibits borderline reversible (time-independent) inhibition of AChE acetylcholin...
T40904 ACG548B
ACG548B (compound 24) is a highly effective inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50 values of 1.78 and 0.496 μM, respectively. It exhibits a greater affinity for AChE and demonstrates sel...
T61638 Dihydro Donepezil
Dihydro Donepezil, also known as Dihydro E2020, is a metabolite derived from Donepezil. Donepezil is a highly specific and potent inhibitor of acetylcholinesterase (AChE) with IC50 values of 8.12 nM and 11.6 nM for butyr...
T39678 Multitarget AD inhibitor-1
Multitarget AD inhibitor-1 is a reversible and selective inhibitor of butyrylcholinesterase (BuChE) with IC50 values of 7.22 μM and 1.55 μM for human BuChE (hBuChE) and equine serum BuChE (eqBuChE), respectively. Additio...
T61418 BuChE-IN-6
BuChE-IN-6 (compound 1b) is a highly effective and specific inhibitor of BuChE (butyrylcholinesterase), demonstrating an IC50 value of 0.46 μM for eqBuChE and 0.51 μM for hBuChE. Furthermore, BuChE-IN-6 has the additiona...
T62538 AChE-IN-15
AChE-IN-15 (Compound 3d) is a reversible inhibitor of human acetylcholinesterase (huAChE) and human butyrylcholinesterase (huBChE) with IC50 values of 6.8 μM and 16.1 μM for huAChE and huBChE, respectively, with signific...
T61342 BChE-IN-13
BChE-IN-13 (Compound 17c) is an orally active, potent, and selective inhibitor of Butyrylcholinesterase (BChE). It exhibits IC50 values of 0.22 μM and 0.016 μM for eqBChE and hBChE, respectively. BChE-IN-13 demonstrates ...
T82915 BChE-IN-21
BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in Alzheimer's disease [1].
T78905 AChE-IN-29
AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric eel acetylcholinesterase (eeAChE), and equine butyrylcholinest...
T64156 AChE/BChE-IN-1
AChE/BChE-IN-1 is a potent dual inhibitor of acetylcholinesterase and butyrylcholinesterase with blood-brain barrier permeability, exhibiting an IC50 value of 1.06 and 7.3 nM for hAChE and hBChE, respectively, and showin...
T78695 BChE-IN-16
BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM. It demonstrates low cytotoxicity and potential for central nervo...
T81998 K1833
K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$. Additionally, K1833 demonstrates potent inhibition (IC50 = 0.57$) and minimal reactivati...
T72804 Isograndifoliol
Isograndifoliol is a chemical compound that acts as a selective inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 0.9 μM and exhibits moderate inhibition of acetylcholinesterase (AChE) with an IC50 value of...
T61603 H3R antagonist 2
H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor antagonist. It exhibits inhibitory effects on acetylcholinesterase, butyrylcholinesterase, and human monoamine oxidase B (hMAO B) with IC50 values of ...
T72876 SEH/AChE-IN-4
sEH/AChE-IN-4 -15 is a potent, blood-brain barrier-penetrating dual inhibitor targeting soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). It demonstrates notable inhibition efficacy, with IC50 values of 3....
T78828 AChE/BChE-IN-15
AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (IC50) of 20 nM for AChE and 220 nM for BChE. It interacts with ...
T79502 PD24
PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for human AChE (hAChE), 1.76 μM for electric eel AChE (eeAChE), and 2.64...
T60983 BChE-IN-14
BChE-IN-14 (compound 19c) can restore cognitive impairment in vivo that can be used in the Alzheimer’s disease research. BChE-IN-14 has primary cell safety and good blood brain barrier permeability. BChE-IN-14 is a selec...
T79548 AChE/BChE-IN-13
AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal inhibitory concentrations (IC50) of 20.89 μM for AChE and 17.3...
T79966 AChE/BChE-IN-14
AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), coupled with...
T79501 PD10
PD10 is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), exhibiting inhibitory potency at human AChE (hAChE IC50: 0.56 μM), electric eel AChE (eeAChE IC50: 0.59 μM), and equine serum BuC...
T62578 BuChE-IN-1
BuChE-IN-1 (Compound 23) is a potent, highly blood-brain barrier-permeable, low cytotoxicity inhibitor of butyrylcholinesterase (BuChE). BuChE-IN-1 is a BuChE inhibitor that has the potential to be used in the study of A...
T79423 BuChE-IN-9
BuChE-IN-9 (compound 22a), an eqBuChE (equine serum-derived butyrylcholinesterase) inhibitor, exhibits potent activity with an IC50 of 173 nM. In addition to eqBuChE, it also inhibits human BACE1, Aβ aggregation, and mou...
T82242 HAChE-IN-6
hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM. It also demonstrates inhibitory effects on human butyrylcholinesterase (hBuChE) and glycogen synthase kin...
T61206 AChE/BChE/BACE-1-IN-1
AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It displays IC50 ...
T79342 BChE-IN-17
BChE-IN-17 (compound 6n) is a potent, selective inhibitor of butyrylcholinesterase (BChE), demonstrating inhibitory half-maximal inhibitory concentrations (IC50s) of 10.5 nM for equine BChE (eqBChE) and 32.5 nM for human...
T64238 Aβ1–42 aggregation inhibitor 1
Aβ1-42 aggregation inhibitor 1 effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), demonstrating IC50 values of 2.64 μM and 1.29 μM, respectively. At a concentration of 25 μM, it also redu...
T72453 AChE/BChE/MAO-B-IN-3
AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, serves as a potent inhibitor of human monoamine oxidase B (MAO-B) with an IC50 of 0.0359 μM, demonstrating significant inhibitory effects on acetylcholinesterase (AChE) an...
T62504 BChE-IN-8
BChE-IN-8 (compound 20) is an orally active BChE (butyrylcholinesterase) inhibitor that crosses the blood-brain barrier and acts on eqBChE (IC50: 0.15 nM), hBChE (IC50: 45.2 nM). BChE-IN-8 can be used in the study of Alz...
T74812 HBChE-IN-1
hBChE-IN-1 (compound 4), a quinolizidinyl derivative, effectively inhibits human Butyrylcholinesterase (hBChE) with an IC50 value of 7 nM, demonstrating high selectivity against human Acetylcholinesterase (hAChE). It als...
T72875 SEH/AChE-IN-3
sEH/AChE-IN-3 (15) serves as a dual inhibitor targeting both soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE), demonstrating potent activity and the ability to cross the blood-brain barrier (BBB). It exhib...
T62441 AChE-IN-14
AChE-IN-14 is a potent cholinesterase inhibitor, acting on electric eel acetylcholinesterase (eeAChE) (IC50: 0.46 μM), human recombinant acetylcholinesterase (hAChE) (IC50: 0.48 μM) and equine serum butyrylcholinesterase...
T72454 AChE/BChE/MAO-B-IN-4
AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, serves as a potent inhibitor for both monoamine oxidase B (MAO-B) and acetylcholinesterase/butyrylcholinesterase (AChE/BChE) enzymes. It exhibits a strong inhibitory effec...

Compounds

Rivastigmine
T0229
Synonym: SDZ-ENA 713,S-Rivastigmine,Exelon
Target: AChE
Rivastigmine tartrate
T1628
Synonym: SDZ-ENA 713,ENA 713
Target: AChR, AChE
PE 154
T23131
Synonym:
Target: AChE
BuChE-IN-TM-10
T10630
Synonym: TM-10
Target: AChR
Ethopropazine Hydrochloride
T21393
Synonym: Lysivane,Parphezein,Dibutil,Parfezin,Profenamine HCl,Pardisol
Target:
RX 67668
T16814
Synonym:
Target: Others
BuChE-IN-7
T73187
Synonym:
Target:
Bisnorcymserine
T26827
Synonym: N1 N8 Bisnorcymserine,N1N8Bisnorcymserine,N1-N8-Bisnorcymserine
Target:
Rivastigmine carbamate impurity
T38740
Synonym: 3-Nitrophenyl ethyl(methyl)carbamate
Target:
BChE-IN-15
T73184
Synonym:
Target:
BChE-IN-4
T61669
Synonym:
Target:
Z164597606
T61399
Synonym:
Target:
TRV-7019
T75145
Synonym:
Target:
Cymserine
T70607
Synonym:
Target:
Affinisine
T69495
Synonym:
Target:
CHF 2819
T30876
Synonym: Ganstigmine HCl,CHF-2819,Ganstigmine hydrochloride,CHF2819
Target:
BuChE-IN-8
T79422
Synonym:
Target:
BChE-IN-3
T62336
Synonym:
Target:
ACG548B
T40904
Synonym:
Target:
Dihydro Donepezil
T61638
Synonym:
Target:
Multitarget AD inhibitor-1
T39678
Synonym:
Target:
BuChE-IN-6
T61418
Synonym:
Target:
AChE-IN-15
T62538
Synonym:
Target:
BChE-IN-13
T61342
Synonym:
Target:
BChE-IN-21
T82915
Synonym:
Target:
AChE-IN-29
T78905
Synonym:
Target:
AChE/BChE-IN-1
T64156
Synonym:
Target:
BChE-IN-16
T78695
Synonym:
Target:
K1833
T81998
Synonym:
Target:
Isograndifoliol
T72804
Synonym:
Target:
H3R antagonist 2
T61603
Synonym:
Target:
sEH/AChE-IN-4
T72876
Synonym:
Target:
AChE/BChE-IN-15
T78828
Synonym:
Target:
PD24
T79502
Synonym:
Target:
BChE-IN-14
T60983
Synonym:
Target:
AChE/BChE-IN-13
T79548
Synonym:
Target:
AChE/BChE-IN-14
T79966
Synonym:
Target:
PD10
T79501
Synonym:
Target:
BuChE-IN-1
T62578
Synonym:
Target:
BuChE-IN-9
T79423
Synonym:
Target:
hAChE-IN-6
T82242
Synonym:
Target:
AChE/BChE/BACE-1-IN-1
T61206
Synonym:
Target:
BChE-IN-17
T79342
Synonym:
Target:
Aβ1–42 aggregation inhibitor 1
T64238
Synonym:
Target:
AChE/BChE/MAO-B-IN-3
T72453
Synonym:
Target:
BChE-IN-8
T62504
Synonym:
Target:
hBChE-IN-1
T74812
Synonym:
Target:
sEH/AChE-IN-3
T72875
Synonym:
Target:
AChE-IN-14
T62441
Synonym:
Target:
AChE/BChE/MAO-B-IN-4
T72454
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
TN1305 Ethoxysanguinarine 6-Ethoxydihydrosanguinarine Apoptosis , AChR
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/-...
TN1341 8-Deoxygartanin Beta Amyloid , NF-κB , Parasite
8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer's disease (AD) a...
T3819 Ursolic acid acetate Acetylursolic acid,3-Acetylursolic Acid AChE
Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition ...
T7052 Gnetol Tyrosinase , COX , HDAC , AChR
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ...
T11366 Garcinol Apoptosis , Endogenous Metabolite , Histone Acetyltransferase , AChR , AChE
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone...
TN3466 Atherosperminine cAMP , Calcium Channel , AChR , Parasite
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with t...
T3S1612 Kuwanon G Moracenin B,Kuwanone G Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
TN3696 Conodurine AChR
Conodurine shows leishmanicidal and antibacterial activities, it shows inhibition activity for acetyl (AChE) and butyrylcholinesterase (BuChE).
TN4570 Minumicrolin Others
Minumicrolin is a plant growth inhibitor against the 2nd leaf sheath elongation of rice seedlings. Murrangatin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100, it might be valuable anti-tumor-promotin...
TN6050 Macusine B
Macusine B is a dual inhibitor, has almost equal inhibitory activity on both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).
TN4613 (-)-N-methylcoclaurine N-Methylcoclaurine Others
N-Methylcoclaurine shows binding affinities for the ĸ opioid receptor with the equilibrium dissociation constant (Ki) value of 0.9 ± 0.1 uM. N-methylcoclaurine also shows promising butyrylcholinesterase inhibition a...
TN2504 1,5-Dihydroxyxanthone EGFR , AChR
1,5-Dihydroxyxanthone exhibits the epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitory activity, with the IC50 value of 90.34 nM. It may have anticholinesterase activity on acetylcholinesterase (AChE) and...
TN1848 Kuwanon E AChR
Kuwanon E inhibited cholinesterase enzyme in a dose-dependent manner with K i values ranging between 3.1 and 37.5 μM and between 1.7 and 19.1 μM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzyme...
T75511 BChE-IN-10
BChE-IN-10 (compound 6), isolated from Bletilla striata, is a potent mixed-type butyrylcholinesterase (BChE) inhibitor exhibiting an IC50 value of 6.4 μM. It is utilized in Alzheimer's disease (AD) research [1].
T75512 Bleformin A
Bleformin A, a natural product isolated from Bletilla striata, serves as a potent butyrylcholinesterase (BChE) inhibitor, exhibiting an IC50 value of 5.2 μM. It is utilized in Alzheimer's disease (AD) research [1].
T75514 Blestrin D
Blestrin D, a potent mixed-type butyrylcholinesterase (BChE) inhibitor with an IC50 value of 8.1 μM, is isolated from Bletilla striata and has applications in Alzheimer's disease (AD) research [1].
TN3287 8-Lavandulylkaempferol Reductase , AChR
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, respectively. It shows inhibitory activities against aldose re...
TN4456 Lucidadiol AChR , HSV
Lucidadiol exhibits butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM, it also possesses inhibitory activity against acetylcholinesterase (AChE) with the percentage inhibition at 100 uM. Lucidadiol...
T75544 AChE/BChE-IN-11
AChE/BChE-IN-11 (compound 1), a natural product derived from artichoke leaves, is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 70 μM for AChE and 71 μM for BChE, re...
T73202 BChE-IN-11
BChE-IN-11, a selective and non-competitive inhibitor of butyrylcholinesterase (BChE), demonstrates potent activity with an inhibitory concentration (IC50) of 2.1 μM. This compound is applicable in Alzheimer's disease (A...
T4700 1,3,5-Trihydroxy-4-prenylxanthone
1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylch...
T75513 BChE-IN-12
BChE-IN-12, also known as compound 12, is a potent non-competitive inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 2.3 μM. Derived from Bletilla striata, it is utilised in research related to Alzheimer's ...
TN3744 Cyclomorusin NOS , AChR
Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of superoxide anion generation in fMLP-stimulated rat neutrophi...
T79973 Dehydrodiscretamine chloride
Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM, respectively. It also possesses antioxidant activity and is ut...
T75436 Jatrorrhizine hydroxide
Jatrorrhizine hydroxide, an alkaloid derived from Coptis chinensis, exhibits a range of biological activities including neuroprotective, antimicrobial, antiplasmodial, and antioxidant properties [1]. It acts as a potent ...
TC0022 Desoxypeganine Deoxypeganine AChE
Desoxypeganine (Deoxypeganine) is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.Desoxypeganine is being...
T79963 Feralolide
Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 μg/mL and 52 μg/mL, ...

Natural Products

Ethoxysanguinarine
TN1305
Synonym: 6-Ethoxydihydrosanguinarine
Target: Apoptosis, AChR
8-Deoxygartanin
TN1341
Synonym:
Target: Beta Amyloid, NF-κB, Parasite
Ursolic acid acetate
T3819
Synonym: Acetylursolic acid,3-Acetylursolic Acid
Target: AChE
Gnetol
T7052
Synonym:
Target: Tyrosinase, COX, HDAC, AChR
Garcinol
T11366
Synonym:
Target: Apoptosis, Endogenous Metabolite, Histone Acetyltransferase, AChR, AChE
Atherosperminine
TN3466
Synonym:
Target: cAMP, Calcium Channel, AChR, Parasite
kuwanon G
T3S1612
Synonym: Moracenin B,Kuwanone G
Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase
Conodurine
TN3696
Synonym:
Target: AChR
Minumicrolin
TN4570
Synonym:
Target: Others
Macusine B
TN6050
Synonym:
Target:
(-)-N-methylcoclaurine
TN4613
Synonym: N-Methylcoclaurine
Target: Others
1,5-Dihydroxyxanthone
TN2504
Synonym:
Target: EGFR, AChR
Kuwanon E
TN1848
Synonym:
Target: AChR
BChE-IN-10
T75511
Synonym:
Target:
Bleformin A
T75512
Synonym:
Target:
Blestrin D
T75514
Synonym:
Target:
8-Lavandulylkaempferol
TN3287
Synonym:
Target: Reductase, AChR
Lucidadiol
TN4456
Synonym:
Target: AChR, HSV
AChE/BChE-IN-11
T75544
Synonym:
Target:
BChE-IN-11
T73202
Synonym:
Target:
1,3,5-Trihydroxy-4-prenylxanthone
T4700
Synonym:
Target:
BChE-IN-12
T75513
Synonym:
Target:
Cyclomorusin
TN3744
Synonym:
Target: NOS, AChR
Dehydrodiscretamine chloride
T79973
Synonym:
Target:
Jatrorrhizine hydroxide
T75436
Synonym:
Target:
Desoxypeganine
TC0022
Synonym: Deoxypeganine
Target: AChE
Feralolide
T79963
Synonym:
Target:

Recombinant Proteins

Species：
Human (1)
Mouse (1)
Expression System：
HEK293 Cells (2)
Tag：
His (2)
Cat No. Product Name Species Expression System
TMPY-01596 Butyrylcholinesterase Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Butyrylcholinesterase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.7 kDa and the accession number is Q03311.
TMPY-01693 Butyrylcholinesterase Protein, Human, Recombinant (His) Human HEK293 Cells
Butyrylcholinesterase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.5 kDa and the accession number is P06276.
CORPORATE
About Us Careers Privacy Notice Events & News Terms & Conditions
SUPPORT
Contact Us Worldwide Distributors Quality Control Technical Support
RESOURCE
Product Catalog Product Citations Signaling Pathways Solution Calculators
FOLLOW OUR
Social Network
Newsletter Subscription
Subscribe to receive our lastest product updates and special offers!
Corporate
Support
Resource
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
TargetMol
Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.