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  • ALK
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Results for "PTK2 protein tyrosine kinase 2" in TargetMol Product Catalog
  • Inhibitor Products
    23
    TargetMol | Activity
  • Natural Products
    3
    TargetMol | inventory
  • PROTAC Products
    1
    TargetMol | natural
Roslin 2 bromide
T2473029574-21-8In house
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5. Roslin 2 bromide exhibits anticancer effects.
  • $97
In Stock
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Defactinib
T19961073154-85-4
Defactinib (VS-6063) is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities.
  • $31
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TargetMol | Citations Cited
NVP-TAE 226
T1918761437-28-9
NVP-TAE 226 (TAE226) is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.
  • $41
In Stock
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TargetMol | Citations Cited
FAK-IN-7
T997319948-85-7
FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.
  • $33
In Stock
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TargetMol | Inhibitor Sale
PF-562271 hydrochloride
T21768939791-41-0
PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
  • $71
In Stock
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TargetMol | Inhibitor Sale
CEP-37440
T26551391712-60-9
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).
  • $31
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ALK inhibitor 1
T10285761436-81-1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
  • $80
In Stock
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GSK2256098
T22811224887-10-8
GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.
  • $39
In Stock
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TargetMol | Citations Cited
PND-1186
T19501061353-68-1
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
  • $48
In Stock
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Fangchinoline
T3122436-77-1
Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.
  • $43
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PF-431396
T2314717906-29-1
PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
  • $50
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TargetMol | Citations Cited
Masitinib
T2609790299-79-5
Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the second part of 2009. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
  • $31
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PF-573228
T2001869288-64-2
PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.
  • $45
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TargetMol | Citations Cited
Chloropyramine hydrochloride
T02636170-42-9
Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.
  • $33
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Nitidine chloride
T5S076113063-04-2
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC.
  • $30
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SU6656
T6997330161-87-0
SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.
  • $34
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Y15
T71194506-66-5
Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity, blocks tumor growth.
  • $43
In Stock
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TargetMol | Citations Cited
ALK inhibitor 2
T3041761438-38-4
ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.
  • $118
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PF-562271 besylate
T6177939791-38-5
PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
  • $53
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BI-4464
T54801227948-02-8
BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC
  • $60
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PF-562271
T2465717907-75-0
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
  • $54
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TargetMol | Citations Cited
AMP-945
T95761393653-34-3
AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.
  • $115
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Batatasin III
TN143356684-87-8
Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancer activities. Batatasin III has a long-term inhibitory effect on whole-plant growth and shows germination
  • $107
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