Search Result

Search Results for " cmk "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T10845	CMK		Others
	CMK, an RSK2 kinase inhibitor, shows similar potency but less chemical stability compared with FMK.		Others
T36347	Ac-YVAD-CMK	Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK	IL Receptor , Caspase , Immunology/Inflammation related , Pyroptosis
	Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity.
T36819	Ac-FLTD-CMK		Caspase
	Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7...		Caspase
T39526	Decanoyl-RVKR-CMK TFA	DecRVKRcmk TFA,Decanoyl-RVKR-CMK TFA
	Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.
T76251L	Ac-FEID-CMK TFA		Pyroptosis
	Ac-FEID-CMK TFA is a selective zebrafish GSDMEb-derived peptide inhibitor that reduces mortality and renal injury in infectious shock.Ac-FEID-CMK TFA inhibits pyroptosis in vivo, attenuates septic AKI (acute kidney injur...		Pyroptosis
T80745	Z-Ala-Ala-Asp-CMK	Z-AAD-CMK	Caspase
	Z-Ala-Ala-Asp-chloromethylketone (Z-AAD-CMK) is a selective inhibitor of granzyme B [1].		Caspase
TP2038	Decanoyl-RVKR-CMK
	Subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin). Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion ...
T36338	AAF-CMK (trifluoroacetate salt)
	Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 μ...
T73412	AAF-CMK
	AAF-CMK, a tripeptidylpeptidase II (TPPII) inhibitor, exhibits anti-tumor activity and induces apoptosis, making it applicable in leukemia research.
T80660	Z-DEVD-CMK
	Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].
T80553	MeOSuc-AAPA-CMK
	MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].
T82592	DEC-RVRK-CMK	Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
	Decanoyl-Arg-Val-Arg-Lys-chloromethylketone (DEC-RVRK-CMK) is a small, synthetic, irreversible cell-permeable competitive inhibitor of furin that exhibits strong antiviral activity against Zika virus (ZIKV) and Japanese ...
T72111	Ala-Ala-Pro-Val-chloromethylketone	AAPV-CMK
	Ala-Ala-Pro-Val-chloromethylketone serves as an irreversible inhibitor of human neutrophil elastase (NE), utilized in researching chronic inflammatory airway diseases.
T80659	Z-YVAD-CMK		Caspase
	Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].		Caspase
T76251	Ac-FEID-CMK
	Ac-FEID-CMK, a potent peptide inhibitor derived from zebrafish-specific GSDMEb, effectively reduces mortality and kidney injury during septic shock by inhibiting pyroptosis and mitigating acute kidney injury (AKI) in viv...
T81822	MeOSuc-AAPF-CMK	MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl
	MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH2Cl) is a potent inhibitor of the enzyme proteinase K [1].
T80743	Z-APF-CMK
	Z-APF-CMK is a selective inhibitor of the calcium (Ca2+)-regulated nuclear scaffold protease (CRNSP), as reported in reference [1].
T78633	MeOSuc-AAPV-CMK	Elastase Inhibitor III
	MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated cleavage of adiponectin [1].
T80101	Z-GGF-CMK		Proteasome
	Z-GGF-CMK, a protease inhibitor, impedes ClpP1P2 and proteasome activity and demonstrates cytotoxic effects on HepG2 cells, with a CC50 value of 125 μM [1].		Proteasome
T72281	Caspase-9 Inhibitor III	Ac-LEHD-cmk
	Caspase-9 Inhibitor III (Ac-LEHD-cmk), a caspase-9 inhibitor, exhibits protective effects against ischemia-reperfusion-induced myocardial injury.
T75706	Ac-DEVD-CMK TFA
	Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible inhibitor of caspase-3, effectively preventing apoptosis triggered by elevated glucose levels or 3,20-dibenzoate (IDB). It is applicable in divers...
T82703	CMKLR1 antagonist 1
	CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-transfected CHO cells. It is applicable in the research of psori...
TQ0061	CHZ868		JAK
	CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.		JAK

Compounds

Synonym: Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK

Target: IL Receptor, Caspase, Immunology/Inflammation related, Pyroptosis

Decanoyl-RVKR-CMK TFA

T39526

Synonym: DecRVKRcmk TFA,Decanoyl-RVKR-CMK TFA

AAF-CMK (trifluoroacetate salt)

Synonym: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone

Target:

Ala-Ala-Pro-Val-chloromethylketone

Synonym: MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl

Synonym: Elastase Inhibitor III

Caspase-9 Inhibitor III

T72281

Synonym: Ac-LEHD-cmk

CMKLR1 antagonist 1

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02234	CXCL9 Protein, Human, Recombinant	Human	E. coli
	CXCL9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.9 kDa and the accession number is Q07325.
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), re...
TMPY-02203	CXCL9 Protein, Mouse, Recombinant	Mouse	E. coli
	CXCL9 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.3 kDa and the accession number is P18340.
TMPH-00603	Cytidylate kinase Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.
TMPJ-01084	CXCL9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b...
TMPH-03265	CMKLR2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates...
TMPH-01082	CMKLR1 Protein, Human, Recombinant (His)	Human	E. coli
	CMKLR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is Q99788.