Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role in the suppression of inflammation,
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway.
Semilicoisoflavone B, an isoflavone extracted from Kohlrabi, has anticancer activity and induces apoptosis in oral cancer cells by inducing ROS production and down-regulating MAPK and Ras Raf MEK signaling.
Magnesium isoglycyrrhizinate hydrate (18α-Glycyrrhizic acid Magnesium hydrate) is an active ingredient derived from licorice with anti-inflammatory properties. It lowers alanine and aspartate aminotransferase activities and can be used in HIV-1 infection research.
Licoflavonol is a flavonoid compound that can be extracted from licorice. It is an inhibitor of Salmonella Typhimurium serotype 3 secretion system and suppresses the secretion of Abeta by inhibiting β-site APP cleaving enzyme 1 (BACE1) transcription.
Isoangustone A is a natural product that inhibits PI3K, MKK4, and MKK7 through ATP competition, suppresses the expression of G1 phase regulatory proteins, inhibits the phosphorylation of Akt, GSK-3β, and JNK1 2, and inhibits the proliferation of human melanoma cells and tumour growth in xenograft mouse models.
Licoisoflavone B is an isoflavonoid from Glycyrrhiza uralensis Fisch.Licoisoflavone B inhibits lipid peroxidation and inhibits human cytochrome P450 enzymes (CYP2C8 and CYP2C9).
Quercitrin hydrate is a natural flavonoid glycoside with multiple activities, including anti-inflammatory, antioxidant, anticancer, neuroprotective, and cardiovascular protective effects, and inhibits aldose reductase.
Glyasperin D is a flavonoid compound extracted from the root of Glycyrrhiza uralensis, which has potential antimicrobial activity against Helicobacter pylori.
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase; it also mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3. Dehydroglyasperin D shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.
Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug ml. Glabranin or a derivative thereof could be used to stimulate hair growth. Glabranine exerts a dose-dependent inhibitory effect
6-Prenylquercetin-3-methylether is a natural product of Glycyrrhiza, Fabaceae. The catalog number is TN3195 and the CAS number is 151649-34-2. 6-Prenylquercetin-3-methylether can be used as a reference standard.
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it shows the inhibition of matrix metalloproteinase (MMP)-2 secretion from brain tumor-derived glioblastoma cells.
Uralsaponin D displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 μmol/L, it could significantly increase the cytotoxic activity after hydrolysis.
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity against KB and L1210 cells. 1-Methoxyphaseollidin also shows inhibition of lysoPAF acetyltransferase activity.