L-Sophoridine (Matridin-15-one) , a natural product obtained from medicinal plants, which has a variety of pharmacological effects, including anti-Y effects, and selectively induces apoptotic cell death in a variety of human Y cells in vitro and in vivo; however, its mechanism of action needs to be further elaborated.

7,3'-Di-O-Methylorobol is a naturally occurring flavonoid found in Sophora japonica that is used in biochemical experiments and organic synthesis.