10-O-Methylprotosappanin B, a natural product of Caesalpinia (Fabaceae), has the catalog number TN5673 and the CAS number 111830-77-4. It can be used as a reference standard.

1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific signaling pathway. 3. Brazilin has anti-inflammatory property, can suppress mastitis and high glucose-induced vascular inflammatory process related with the inhibition of oxidative stress, CAMs expression, and NF-κB activation in HUVEC; may be useful to treat chronic inflammatory disorders including rheumatoid arthritis.

Protosappanin A (PTA) has anti-oxidative nitrative activities on brain immune and neuroinflammation through regulation of CD14 TLR4-dependent IKK IκB NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM.

1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, via activation of a MDM2-dependent ubiquitination process.

4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.

Ombuin has anti-inflammary activity, it inhibits some macrophage functions involved in the inflammatory process.

Bonducellpin D may show inhibitory activities on the Para3 virus. It also exhibits moderate activity against four tested human cancer cell lines, HepG-2, K562, HeLa, and Du145.

Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.

Delta-Caesalpin is a natural product for research related to life sciences. The catalog number is TN3817 and the CAS number is 7716-14-5.

Bonducellpin C is a natural product from Caesalpinia minax.

'3'-Deoxy-4-O-methylsappanol exhibits moderate cytotoxicity against cultured human melanoma HMV-II cells, with an IC50 value of 872.0 µM ± [2.4].

Episappanol has anti-inflammatory activity , it can significantly inhibit the secretion of the pro-inflammatory cytokines interleukin (IL-6) and tumor necrosis factor-alpha (TNF-α).

14-Deoxy-epsilon-caesalpin is a natural product from Caesalpinia minax HANCE.

Caesalpine B is a natural product from Caesalpinia minax.

4-O-Methylsappanol shows activity against this fungus against Beauveria bassiana.

7,3',4'-Trihydroxy-3-benzyl-2H-chromene is a potential xanthine oxidase inhibitor.

Minaxin C is a natural product from Caesalpinia minax HANCE.

3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.

Caesalmin E shows anti-Para3 virus activity.

7-Hydroxy-3-(4'-hydroxybenzylidene)-chroman-4-one may have anti-inflammatory activity.

Neocaesalpin L is a natural product from Caesalpinia minax HANCE.

Caesalmin B shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.

4-(trans)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone is a natural product from Caesalpinia minax.

5-Hydroxy-7-methoxy-3-(4-hydroxybenzylidene)chroman-4-one is a natural product for research related to life sciences. The catalog number is TN3121 and the CAS number is 259653-54-8.

5-O-Methyldalbergiphenol is a natural product for research related to life sciences. The catalog number is TN3132 and the CAS number is 1499946-35-8.

Isovouacapenol C is a natural product of Caesalpinia, Fabaceae. The catalog number is TN4338 and the CAS number is 455255-15-9. Isovouacapenol C can be used as a reference standard.

12-Demethylneocaesalpin F is a natural product for research related to life sciences. The catalog number is TN5599 and the CAS number is 1228964-10-0.

Protosappanin A dimethyl acetal shows significant xanthine oxidase inhibitory activity in a concentration-dependent manner.

Neocaesalpin O is a natural product from Caesalpinia minax HANCE.

2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.

2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities.

7-O-Acetylneocaesalpin N is a natural product for research related to life sciences. The catalog number is TN3242 and the CAS number is 1309079-08-0.

7-O-Acetylbonducellpin C may exhibit significant inhibition of nitric oxide production of RAW264.7 macrophages stimulated by lipopolysaccharide (LPS).

3-Deoxysappanone B has vasorelaxation effects, it can mediate endothelium- independent vasodilator action in rat thoracic aortic rings.

Caesalpine A is a natural product from Caesalpinia minax.

Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bonducellin shows weak antimalarial ac

Caesalpin J is a natural product for research related to life sciences. The catalog number is TMA2282 and the CAS number is 99217-67-1.

Monomethyl kolavate is a power Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) inhibitor, with an IC50 value of 12uM.

Norcaesalpinin E shows antimalarial activity against the malaria parasite Plasmodium falciparum FCR-3/A2 clone in vitro, with an IC50 value of 0.090 microM.