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GPCR19

The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene.
Cat. No. Product name CAS No. Purity Chemical Structure
T8752 BAR 501 impurity 1632118-70-7 98%
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501...
TQ0252 BAR502 1612191-86-2 98%
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
T7428 SBI-115 882366-16-7 98%
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T2965 Deoxycholic acid 83-44-3 98%
Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent t...
T4083 BAR501 1632118-69-4 98%
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
T4352 SB756050 447410-57-3 98%
SB756050 is a specific TGR5 agonist.
T8818 TC-G 1005 1415407-60-1 98%
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re...
T1824 TGR5 Receptor Agonist 1197300-24-5 98%
TGR5 is a potent TGR5(GPCR19) agonist.
T2968 Hyodeoxycholic acid 83-49-8 98%
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
T5077 Deoxycholic acid sodium salt 302-95-4 98%
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
T29078 Ursodeoxycholic acid sodium 2898-95-5 98%
Ursodeoxycholic acid sodium is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts a...
TP1949L PEN (human) aceate 98%
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.
T11662L INT-777 1199796-29-6 98%
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/...
BAR 501 impurity
T8752
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501...
BAR502
TQ0252
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
SBI-115
T7428
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
Deoxycholic acid
T2965
Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent t...
BAR501
T4083
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
SB756050
T4352
SB756050 is a specific TGR5 agonist.
TC-G 1005
T8818
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re...
TGR5 Receptor Agonist
T1824
TGR5 is a potent TGR5(GPCR19) agonist.
Hyodeoxycholic acid
T2968
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
Deoxycholic acid sodium salt
T5077
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
Ursodeoxycholic acid sodium
T29078
Ursodeoxycholic acid sodium is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts a...
PEN (human) aceate
TP1949L
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.
INT-777
T11662L
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/...