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GPCR/G Protein GPCR19

GPCR19

The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene.
Cat No. product name
T11662L INT-777 INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
T1824 TGR5 Receptor Agonist TGR5 is a potent TGR5(GPCR19) agonist.
T2965 Deoxycholic acid Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent ...
T2968 Hyodeoxycholic acid Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
T4083 BAR 501 BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
T4352 SB756050 SB756050 is a specific TGR5 agonist.
T5077 Sodium Desoxycholate Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
T5100 DJ-V159 DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).
T7428 SBI-115 SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T8752 BAR 501 impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR5...
T8752 BAR 501 impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR5...
T8818 TC-G 1005 TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and r...
TQ0252 BAR502 BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
INT-777
T11662LCAS 1199796-29-6
INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
TGR5 Receptor Agonist
T1824CAS 1197300-24-5
TGR5 is a potent TGR5(GPCR19) agonist.
Deoxycholic acid
T2965CAS 83-44-3
Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent ...
Hyodeoxycholic acid
T2968CAS 83-49-8
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
BAR 501
T4083CAS 1632118-69-4
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
SB756050
T4352CAS 447410-57-3
SB756050 is a specific TGR5 agonist.
Sodium Desoxycholate
T5077CAS 302-95-4
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
DJ-V159
T5100CAS 2253744-53-3
DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).
SBI-115
T7428CAS 882366-16-7
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
BAR 501 impurity
T8752CAS 1632118-70-7
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR5...
BAR 501 impurity
T8752CAS 1632118-70-7
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR5...
TC-G 1005
T8818CAS 1415407-60-1
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and r...
BAR502
TQ0252CAS 1612191-86-2
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).