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GPCR19

The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene.
Cat No. product name
T2965 Deoxycholic acid Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent t...
T7428 SBI-115 SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T5077 Deoxycholic acid sodium salt Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
TQ0252 BAR502 BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
T4083 BAR501 BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
T8752 BAR 501 impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501...
T2968 Hyodeoxycholic acid Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
T1824 TGR5 Receptor Agonist TGR5 is a potent TGR5(GPCR19) agonist.
T8818 TC-G 1005 TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re...
T11662L INT-777 INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
T4352 SB756050 SB756050 is a specific TGR5 agonist.
Deoxycholic acid
T2965
Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent t...
SBI-115
T7428
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
Deoxycholic acid sodium salt
T5077
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
BAR502
TQ0252
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
BAR501
T4083
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
BAR 501 impurity
T8752
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR50...
Hyodeoxycholic acid
T2968
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
TGR5 Receptor Agonist
T1824
TGR5 is a potent TGR5(GPCR19) agonist.
TC-G 1005
T8818
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re...
INT-777
T11662L
INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
SB756050
T4352
SB756050 is a specific TGR5 agonist.