Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
TP2262L | IRL-1038 acetate | TP2262L | 97.51% |
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IRL-1038 acetate is a potent ETB endothelin receptor antagonist. | ||||
T78096 | BQ-3020 ammonium | 98% |
|
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BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2 ... | ||||
T80438 | Atrial natriuretic peptide (3-28) (human) | 102686-43-1 | 98% |
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Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation of b... | ||||
T81538 | Patecibart | 2642374-04-5 | 98% |
Patecibart
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Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA). | ||||
TN4606 | Myriceric acid C | 162059-94-1 | 98% |
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Myriceric acid C has cytotoxic activity against human lung carcinoma and breast carcinoma. | ||||
T11934 | Macitentan-d4 | 1258428-05-5 | 98% |
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Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor... | ||||
T0750 | Sulfisoxazole | 127-69-5 | 99.98% |
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Sulfisoxazole (Sulfafurazole) is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.Sulfiso... | ||||
T1655 | Ambrisentan | 177036-94-1 | 99.85% |
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Ambrisentan (BSF 208075) is an endothelin receptor antagonist used in the therapy of pulmonary arterial hypertension (PAH). Ambrisentan has been associated with ... | ||||
T2561 | Macitentan | 441798-33-0 | 99.81% |
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Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH). | ||||
T6265 | Bosentan (hydrate) | 157212-55-0 | 99.75% |
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Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors. | ||||
TQ0282 | Avosentan | 290815-26-8 | 99.47% |
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Avosentan (Ro 67-0565) is an effective and selective antagonist of the endothelin receptor (ETA receptor). | ||||
T6258 | Zibotentan | 186497-07-4 | 99.34% |
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Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3. | ||||
T34541 | SB-209670 | 157659-79-5 | 99.24% |
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SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle. | ||||
T7817 | Aprocitentan | 1103522-45-7 | 99.17% |
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Aprocitentan (ACT-132577) is ETA and ETB antagonist . | ||||
T5355 | Sparsentan | 254740-64-2 | 98.81% |
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Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respective... | ||||
T3194 | Ro 46-2005 | 150725-87-4 | 98.8% |
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Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA recep... | ||||
T31605 | Edonentan | 210891-04-6 | 98.69% |
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Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure. | ||||
TQ0270 | Atrasentan hydrochloride | 195733-43-8 | 98.64% |
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Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA). | ||||
T3474 | RO 46-8443 | 175556-12-4 | 98.5% |
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RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms... | ||||
T26841 | BMS 182874 | 153042-42-3 | 98.38% |
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BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for E... |