vitamin d-3

Vitamin D3 (cholecalciferol) is a naturally occurring form of vitamin D; once metabolically activated, it can induce cellular differentiation and cancer cell proliferation. Vitamin D3 can be used to establish kidney stone models and is also an important research target in the fields of immunology and oncology.

Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption with parathyroid hormone.

5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol) is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.

7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.

3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 is a derivative of Vitamin D3.

3-epi-25-hydroxy Vitamin D3 is the C-3 epimer of 25-hydroxy vitamin D3. Dietary administration of 3-epi-25-hydroxy vitamin D3 (0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats.

1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion [1].

Vitamin D3 octanoate, an ester derived from vitamin D3, is commonly known as cholecalciferol. Cholecalciferol is a naturally occurring form of vitamin D with notable properties such as inducing cell differentiation and impeding cancer cell proliferation.

(1S)-Calcitriol-d3 (1α,25-Dihydroxy-3-epi-vitamin D3-d3) is the deuterium-labeled version of (1S)-Calcitriol. Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3]. It exhibits effective vitamin D receptor (VDR)-mediated actions, such as inhibiting keratinocyte proliferation and suppressing parathyroid hormone secretion.

(1S)-Calcitriol-d6 (1α,25-Dihydroxy-3-epi-vitamin D3-d6) is a deuterium-labeled form of (1S)-Calcitriol, a natural metabolite of 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3]. This compound exhibits significant Vitamin D receptor (VDR)-mediated activities, such as inhibiting keratinocyte growth and suppressing parathyroid hormone secretion.

Impurity B of Calcitriol is an impurity of Calcitriol. Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

Secalciferol is a Vitamin D metabolite,Secalciferol is a possibly anti-inflammatory steroid which is involved in bone ossification.

VD3-D6 is the deuterated form of VD3 (TMSM-2393); tools for determination of Vitamin D3 metabolites in human serum.

25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a vitamin D3 metabolite and a precursor compound for the synthesis of 25-hydroxyvitamin D.

Chol-5-en-24-al-3β-ol, a steroid compound, exhibits properties characteristic of steroids.

Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.

Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.

Eldecalcitol possesses a potent inhibitory effect on bone resorption and induces a significant increase in bone mineral density. Eldecalcitol is an orally active analogue of active vitamin D. It also is used in the treatment of osteoporosis .

Calcitriol Impurities D (24-Homo Calcitriol) is a hormonal form of the vitamin that promotes the differentiation of HL-60 human promyelocytic leukemia cells into monocytes.Calcitriol Impurities D has bone resorption activity and inhibits the replication of human immunodeficiency virus in human cells.Calcitriol Impurities D has antiviral activity and can be used to treat AIDS and viral infections. 25-dihydroxyvitamin D3 has antiviral activity and can be used in the treatment of AIDS and viral infections.

(24S)-24,25-Dihydroxyvitamin D3 undergoes multiple hydroxylation processes to form active vitamin D3 analogs.

20-Hydroxyvitamin D3 (20(OH)D3) is a hydroxy metabolite of vitamin D3. It functions as a ligand for the vitamin D receptor (VDR), aryl hydrocarbon receptor (AhR), liver X receptor (LXR), and retinoic acid receptor-related orphan receptor (ROR). 20-Hydroxyvitamin D3 inhibits cell proliferation and induces differentiation. It is applicable in research on inflammatory and autoimmune diseases.

Inecalcitol is a unique vitamin D3 analog that induces apoptosis and has anticancer activity. It is an orally active vitamin D receptor agonist with a Kd of 0.53 nM.

23,25-Dihydroxy-24-oxovitamin D3, a prominent metabolite of 24(R),25-Dihydroxyvitamin D3, holds significant potential for studying metabolic disorders[1].

Previtamin D3 [Cholecalciferol (vitamin D3) intermediate].