lcarnitine

L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utilized as an energy substrate in all tissues except the brain.

Oleoylcarnitine (Oleoyl-L-carnitine) inhibits adenine nucleotide translocase (AdNT) activity with an ic50 of 14 μM.Oleoylcarnitine is an important indicator of neurodegeneration.

Palmitoylcarnitine (Palmitoyl DL-carnitine) is a mitochondrial fatty acid oxidation intermediate that acts as a surfactant.

Valerylcarnitine (VALERYL-L-CARNITINE) is a short-chain fatty acid used in the study of type 2 diabetes.

Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) is a mitochondrial fatty acid oxidation intermediate that mediates intralipid cardioprotection.Palmitoylcarnitine chloride eliminates colorectal cancer cell survival by depletion of glutathione. induces cancer cell death and regulates the interaction between protein kinase C βII and its receptor RACK1.

Butyrylcarnitine is a plasma metabolite that is an indicator of abnormal metabolism due to disease and is used in the diagnosis of heart failure and pancreatic cysts.

Dodecanoylcarnitine ((-)-Lauroylcarnitine) has been associated with disturbances in fatty acid oxidation, and the use of Dodecanoylcarnitine resulted in an increase in the permeability of salmon calcitonin.

Tetradecanoylcarnitine (L-Myristoylcarnitine) is an acylcarnitine involved in the beta-oxidation of long-chain fatty acids, and is a potential marker for very-long-chain coenzyme A dehydrogenase deficiency. alpha-Dihydroartemisinin is a potent and selective inhibitor with multiple targets.

Glutarylcarnitine (O-glutaroyl-L-carnitine) is a diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.

Isovalerylcarnitine (3-methylbutyrylcarnitine) is a small molecule compound produced by the catabolism of L-leucine and the accumulation of isovaleric acid. Isovalerylcarnitine is also a selective and effective calpain activator that can promote cell apoptosis. Isovalerylcarnitine is related to isovaleric acidemia and can be used as a marker of isovaleric acidemia.

L-Hexanoylcarnitine is a form of acylcarnitine used as a supplement for athletes and fitness enthusiasts to enhance physical performance and promote fat metabolism.

L-Octanoylcarnitine is the active octanoylcarnitine present in plasma and is a potential biomarker for breast cancer.

Stearoylcarnitine (Stearoyl-L-carnitine) is a fatty ester lipid molecule, a human endogenous metabolite that serves as a biomarker for early-onset preeclampsia and late-onset preeclampsia.

(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) is a mixture of short-chain acylcarnitines used as a dietary supplement for the study of chronic diabetes.

L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO).

L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and fatty acid metabolite, accumulates in the sarcolemma and disrupts the membrane lipid environment during ischemia. It inhibits K ATP channel activity by interacting with Kir6.2 without altering single-channel conductance [1].

3-Hydroxyisovalerylcarnitine is a carnitine derivative that may serve as a novel biomarker for biotin deficiency in humans, with its concentration increasing in such conditions. Biotin deficiency reduces the activity of biotin-dependent 3-methylcrotonyl-CoA carboxylase, hindering the conversion of 3-methylcrotonyl-CoA into 3-methylglutaconyl-CoA, and impairing the leucine catabolism pathway, resulting in elevated plasma 3-Hydroxyisovalerylcarnitine concentrations [1].

cis-Malonylcarnitine is an ester compound.

(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. Carnitine is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It has also been used to allow the en