Search Result

Search Results for " homologue "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T6357	(S)-crizotinib	ent-crizotinib	Apoptosis , DNA/RNA Synthesis , MTH1
	(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.		Apoptosis , DNA/RNA Synthesis , MTH1
T0369	Ethaverine hydrochloride	Consenil,Ethaquin,Papetherine	MAO
	Ethaverine hydrochloride (Ethaquin) is a homologue of papaverine.		MAO
T1366	3-Pyridylacetic acid hydrochloride		DPP-4
	3-Pyridylacetic acid hydrochloride (3-PAA-HCl) is a high homologue of niacin. It is a decomposition product of nicotine (and other tobacco alkaloids). It can also react with amines, alcohols and carboxylic acids, and can...		DPP-4
T67929	Linoleoyl glycine
	Linoleoyl glycine, a modified polyunsaturated fatty acid, is an endogenous homologue of linoleoyl glycine. Linoleoyl glycine activates human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in xenopus oocytes from mammalia...
T70163	Bizine dihydrochloride
	Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2.
T38685	C12-Sphingosine	C12-Sphingosine
	C12-Sphingosine is a short-chain homologue of Sphingosine. It effectively inhibits the activity of serine palmitoyltransferase in primary cultured cerebellar cells.
T69376	Viriditoxin
	Viriditoxin is a secondary metabolite isolated from Aspergillus viridinutans that has been shown to inhibit FtsZ, the bacterial homologue of eukaryotic tubulin.
T19188	ALLO-1		Autophagy
	ALLO-1 is a crucial autophagy receptor responsible for facilitating the formation of autophagosomes around paternal organelles. It directly interacts with the worm LC3 homologue, LGG-1, through its LC3-interacting region...		Autophagy
T81743	MTORC1-IN-1		mTOR
	mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and metabolism, with implications in various diseases such as cancer. It interacts with mTORC1 by attaching to the...		mTOR
T79730	LB244		STING
	LB244, a homologue of BB-Cl-amidine, functions as an orally effective STING inhibitor with an EC50 value of 0.8 μM, applicable in the treatment of STING-dependent inflammatory diseases. However, pharmacokinetic studies h...		STING
T82613	Danburstotug	STI-3031,IMC-001	PD-1/PD-L1
	Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 (PDL1, B7 homologue 1, B7H1).		PD-1/PD-L1
T36649	AN3661
	AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains...
T36798L	SW2_110A acetate		Histone Methyltransferase
	SW2_110A acetate is a selective, cell-permeable chromobox inhibitor of homologue CBX8 (Kd = 800 nM) bound to CBX8 N-terminal color gamut (ChD). SW2_110A acetate has a high affinity for CBX8N, inhibits the association bet...		Histone Methyltransferase

Compounds

(S)-crizotinib

T6357

Synonym: ent-crizotinib

Target: Apoptosis, DNA/RNA Synthesis, MTH1

Ethaverine hydrochloride

T0369

Synonym: Consenil,Ethaquin,Papetherine

Target: MAO

3-Pyridylacetic acid hydrochloride

Bizine dihydrochloride

Synonym: C12-Sphingosine

Synonym: STI-3031,IMC-001

Target: Histone Methyltransferase

Cat No.	Product Name	Targets
T8103	H-HoArg-OH	Endogenous Metabolite , Phosphorylase
	H-HoArg-OH, a homologue arginine, is a strong inhibitor of human liver and bone alkaline phosphatase.	Endogenous Metabolite , Phosphorylase
T8100	Azetidine-2-carboxylic acid	Others
	Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including hu...	Others
T83531	(Rac)-Juvenile hormone III
	(Rac)-Juvenile hormone III, derived from farnesoic acid, represents the most prevalent homologue of juvenile hormones [1].

Natural Products

H-HoArg-OH

T8103

Synonym:

Target: Endogenous Metabolite, Phosphorylase

Azetidine-2-carboxylic acid

T8100

Synonym:

Target: Others

(Rac)-Juvenile hormone III

T83531

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00169	OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPK-00168	OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPK-00167	OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPK-00463	OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPJ-01053	UBE2I Protein, Human, Recombinant (GST)	Human	E. coli
	SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin ho...
TMPK-01395	TENM2 Protein, Human, Recombinant (His)	Human	HEK293
	Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosoph...
TMPK-01414	Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)	Mouse	HEK293
	Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of t...
TMPY-04671	MCP-5 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impa...
TMPY-03628	APLP1 Protein, Human, Recombinant (His)	Human	HEK293
	APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amy...
TMPJ-01200	IMPA3 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded...
TMPY-04693	APLP1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amy...
TMPY-04205	AGR3 Protein, Human, Recombinant (mFc)	Human	HEK293
	Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associat...
TMPJ-01022	SUMO3 Protein, Human, Recombinant (HEK293, His)	Human	Human Cells
	Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way...
TMPY-02496	Rad6/UBE2A Protein, Human, Recombinant (His)	Human	E. coli
	Ubiquitin-conjugating enzyme E2 A (also known as HHR6A or UBE2A), encoded by human DNA repair genes HHR6A, belongs to the ubiquitin-conjugating enzymes (E2 enzymes) family and is likely to be involved in postreplication ...
TMPY-01733	SIGNR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02859	TFPI2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-01004	TFPI2 Protein, Human, Recombinant (His)	Human	HEK293
	Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-02329	TFPI2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...