e-101

Riboflavin (Vitamin B2) is a natural product, an endogenous human metabolite, and a micronutrient. Riboflavin is essential for the formation of two major coenzymes, flavin mononucleotide and flavin adenine dinucleotide. Riboflavin is involved in energy metabolism, cellular respiration, and antibody production, as well as normal growth and development.

Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug.

SWE101 is a potent human and rat soluble epoxide hydrolase (sEH)-P inhibitor(IC50s of 4 μM and 2.8 μM, respectively).

E3LigaseLigand-linker Conjugate 101 is a conjugate consisting of an E3 ligase ligand and a linker, specifically made up of (S,R,S)-AHPC and a corresponding linker. (S,R,S)-AHPC is a von Hippel-Lindau (VHL) ligand based on VH032, capable of recruiting VHL protein. This conjugate is a crucial intermediate for synthesizing complete PROTACs molecules.

Zeleciment basivarsen (DYNE-101) is an antibody oligonucleotide conjugate (AOC), consisting of a Fab antibody named Zeleciment that binds to the transferrin receptor 1 (TfR1) on muscle cells, and an antisense oligonucleotide known as Basivarsen. This compound targets the RNA of the mutant dystrophia myotonica-protein kinase (DMPK) for RNase H-mediated degradation, and is utilized in the study of myotonic dystrophy type 1 (DM1).

FE101120 is a non-peptidic CCK2 receptor agonist. It is utilized in diabetes research.

5H-Dibenz[b,f]azepine-10,11-dione is a useful organic compound for research related to life sciences and the catalog number is T64469.

Sulforhodamine 101 DHPE, a fluorescent probe, results from the conjugation of sulforhodamine 101, a red fluorescent dye with excitation/emission spectra of 586/605 nm, to the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE. It effectively integrates into phospholipid bilayers and is utilized for imaging solid supported lipid bilayers, detecting protein-ligand interactions on bilayers, and monitoring lipid probe colocalization in liposomes through resonance energy transfer (RET).

(E,E)-10,12-Hexadecadienal, isolated as a female pheromone from Earias insulana, is a chemical compound.

(E,E)-10,12-Hexadecadienol, identified as a female pheromone, has been isolated from the legume pod borer.

(Z,E)-10,12-Hexadecadienal functions as a pheromone in Conogethes pluto and serves as an attractant.

(E,E,E,)-10,12,14-Hexadecatrienal, a pheromone emitted by female Manduca sexta, is a chemical compound.

Entrectinib (RXDX-101) is a Trk, ROS1, and ALK inhibitor that inhibits TrkA, TrkB, TrkC, ROS1, and ALK (IC50=1/3/5/12/7 nM) with oral activity and blood-brain-barrier penetration. Entrectinib exhibits both antitumor and CNS activity.

Zilovertamab vedotin is a novel antibody-drug conjugate (ADC) constructed by conjugating the humanized monoclonal antibody zilovertamab with the anti-microtubule cytotoxic drug monomethyl vedotin. It binds to ROR1 on the surface of tumor cells, promotes rapid internalization and trafficking of the complex to lysosomes, followed by ADC cleavage and release of monomethyl vedotin, thereby inducing tumor cell apoptosis. It can be used in cancer-related research.