detergent

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.

Dodecylphosphocholine (DPC) is a substrate-type inhibitor of pancreas phospholipase A2. Dodecylphosphocholine is a detergent.

1-Dodecylimidazole (N-Dodecylimidazole) is a chemical compound that acts as a cytotoxic agent and lysosomotropic detergent, inducing cell death through acid-dependent lysosomal accumulation, disrupting the lysosomal membrane, and releasing cysteine proteases into the cytoplasm. It also exhibits hypocholesterolemic and broad-spectrum antifungal activities.

Digitonin is a natural product of the glycoside family and is a detergent. Digitonin has antitumor activity, binds to cholesterol molecules to increase the permeability of cell membranes, and is active in the cleavage of cell membranes in a wide range of cells.

Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. Chenodeoxycholic acid acts as a detergent to dissolve fat for intestinal absorption and is reabsorbed by the small intestine. Chenodeoxycholic acid is used as a choledocholithiasis, choledocholithiasis and laxative, as well as to prevent or dissolve gallstones.

Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B Sulfate (Poly-RX) is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.

Taurocholic acid sodium salt hydrate is a bile acid sodium salt hydrate that participates in fat emulsification and can be used to establish pancreatitis models.

N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is an alkyl maltopyranoside detergent, particularly useful in transporters and respiratory complexes. It is a derivative of pyrene (Py) and has applications in the purification and stabilization of RNA polymerase, as well as the detection of protein-lipid interactions.

Trisodium Phosphate is a strong alkali commonly used as a detergent, and has antibacterial activity against E. coli and S. aureus.

Sodium lauroyl glutamate (Acylglutamate LS-11) is an amino acid detergent and increases the solubility of long-chain alkyl gallates such as alkyl gallates.

Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM), EphA2 antagonists (IC50=48, 66 μM) and EphB4 antagonists (IC50=141 μM). Lithocholic acid can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is a cleanser that dissolves fat for absorption and is itself absorbed.

Sodium Dihydrogen Phosphate has inhibitory activity against hCA1 2 4 5A 9 and is commonly used as a detergent or phosphorus supplement.

Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.

Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant [1] [2].

Octyl-beta-D-glucopyranoside (11β-HSD1-IN-11) is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins.

Sulfobetaine-12 (Zwittergent 3-12 Detergent) is a zwitterionic surfactant, dispersant and emulsifier commonly used in industry.

N-Lauroylsarcosine is an amphiphilic anionic surfactant derived from sarcosine , commonly used as a foaming agent and detergent for the preparation of ph-sensitive vesicles and micellar aggregates with antiviral activity against HSV.

N-Octyl-β-D-thioglucopyranoside (octylthioglucoside, OTG) is a mild nonionic detergent characterized by a thioglycosidic linkage that is used for effective cell lysis or to solubilise integral membrane proteins without denaturing their tertiary or quaternary structure; this property is particularly of use in order to crystallise them for structural studies or to reconstitute them into artificial lipid bilayers for functional assays.

Lauroylsarcosine sodium salt(Sarkosyl NL sodium) is an anionic surfactant and detergent with protein denaturing properties commonly used in molecular biology research for purification of membrane proteins, promotion of cell lysis in RNA purification experiments and membrane solubilization, and toxicity to A549 cells after ALIF or SME exposure.

n-Decyl-β-D-Maltopyranoside is a mild non-ionic detergent that preserves the natural conformation of membrane proteins, making it suitable for dissolving and extracting membrane proteins.

NDSB-256 (3-(Benzyldimethylammonio)propane-1-sulfonate) is a non-detergent sulfobetaine that prevents protein aggregation and increases the isomerization rate in a concentration-dependent manner.

Taurodeoxycholate sodium salt (Sodium taurodeoxylate) is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. and it inhibits various inflammatory responses

Sodium tripolyphosphate can chelate metal ions and is commonly used as a detergent additive and water softener. It can also be used to prepare buffer solutions with a pH of 9.2–10.5.

Sodium nonanoate is a salt-like compound primarily employed as a surfactant or emulsifier across diverse industrial applications, including detergent, soap, and personal care product manufacturing. Additionally, Sodium nonanoate functions as an intermediate in the synthesis of various organic compounds, such as pharmaceuticals and agrochemicals. Sodium nonanoate's distinctive chemical properties render it a critical component in multiple industrial processes, particularly in textile and paper product fabrication.