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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19836 | 2-Aminopurine | DNA/RNA Synthesis , PKA | |
2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor. | |||
T12235 | NMDI14 | Others | |
NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD). | |||
T30549 | BMY-21502 | Bms-181168,Bms 181168,Bmy 21502,Bmy21502,Bms181168 | Antioxidant |
BMY-21502 is a potential cognitive enhancer that shows anti-hypoxia effects in the KCN-hypoxia model, delays the decay of hippocampal synaptic enhancement in vitro, and can be used to study Alzheimer's disease. | |||
T16348 | NS5806 | NS-5806 | Potassium Channel |
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChIP2 peak current amplitudes (EC50: 5.3 μM). | |||
TN7087 | 2,5-dimethoxycyclohexa-2,5-diene-1,4-dio | 2,5-DMBQ,Thermophillin,2,5-Dimethoxybenzoquinone,2,5-Dimethoxybenzo-1,4-quinone | Others |
2,5-dimethoxycyclohexa-2,5-diene-1,4-dio (Thermophillin) is a natural product. The redox cycle of 2,5-dimethoxybenzoquinone is a source of reducing equivalent for the regeneration of Fe2+ and H2O2 in brown rot fungal dec... | |||
T77678 | TZ3O | AChR | |
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ... | |||
T0109 | Molsidomine | Morsydomine,SIN-10,Corvaton | NOD |
Molsidomine (Corvaton) is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound. | |||
T3644 | U93631 | GABA Receptor | |
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude... | |||
TN2798 | 20-Deoxocarnosol | ROS , Antifection | |
20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity. | |||
TN2625 | 14-Deoxycoleon U | Antifection | |
14-Deoxycoleon U has anti-termitic activity, it is highly active against both wood-decay fungi. 14-Deoxycoleon U shows antibacterial activity against the Gram-positive bacteria Staphylococcus aureus, Staphylococcus epide... | |||
T11170 | EIF4A3-IN-1 | Others | |
eIF4A3-IN-1 is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD... | |||
T64049 | KIRA9 | ||
KIRA9 is a potent inhibitor of IRE1 with an IC50 value of 4.8 μM for INS-1 cells. KIRA9 completely binds the ATP binding site of IRE1 and blocks endoplasmic reticulum (ER) localised mRNA decay and apoptosis. | |||
T71398 | RO5126946 | ||
RO5126946 is a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator. RO5126946 allosterically modulates α7nAChR activity. RO5126946 increased acetylcholine-evoked peak current and delayed current decay... | |||
T79062 | IRE1α kinase-IN-8 | IRE1 | |
IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, serves as a potent inhibitor of IRE-1α. This compound is utilized in research pertaining to diseases linked to the unfolded protein response and regulated I... | |||
T36501 | CYPMPO | RR 071 | |
CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first o... | |||
T79063 | IRE1α kinase-IN-9 | IRE1 | |
IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM. It is suitable for research into diseases linked to the unfolded protein response or regulated IRE1... | |||
T35419 | τ-Fluvalinate | ||
τ-Fluvalinate is a pyrethroid acaricide.1It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed inXenopusoocytes (EC50= 60 nM). It also induces tail currents in honey... |