ddb

DDB is a biochemical.

Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.

PDdB-Pfp is a reducible ADC (antibody-drug conjugate) linker designed for agents targeting the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1).

bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.

CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low concentrations.

Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.

PROTAC BRD9 Degrader-1 is a leading PROTAC BRD9 chemical degrader with an IC50 of 13.5 nM.

CCT367766 formic is a potent third-generation heterobifunctional Cereblon-based protein degradation probe (PDP, or PROTAC) that selectively targets pirin for degradation, effectively diminishing its protein expression at low concentrations. This compound demonstrates moderate affinity towards the CRBN-DDB1 complex, as denoted by an IC50 value of 490 nM, while exhibiting strong binding to recombinant pirin and CRBN, with respective Kd values of 55 nM and 120 nM. As such, CCT367766 formic serves as a valuable chemical probe for investigating the functions of the largely unexplored pirin protein [1].

Fmoc-D-Dbu(N3)-OH is a click chemistry reagent with an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc). This compound can also undergo strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

Z-D-Dbu(N3)-OH is a click chemistry reagent featuring an azide group. It can be employed across various biochemical studies.

PTD-DBM is a competitive peptide that blocks the interaction between CXXC5 and Dvl, thereby inducing the expression of β-catenin, α-SMA, and type I collagen. Additionally, PTD-DBM promotes skin wound healing activity.