d-13

D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection. |1. Lazzarini, C., Haranahalli, K., Rieger, R., et al. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrob. Agents Chemother. 62(5), e00156-00118 (2018).

Colfosceril miristate-D13 (DMPC-D13) is the deuterated form of Colfosceril miristate. Colfosceril miristate (T9525) (DMPC) is a synthetic phospholipid utilized in the study of liposomes and lipid bilayers. It is employed for research on lipid monolayers and bilayers.

Choline-D13 Bromide (N,N,N-trimethyl-D9; 1,1,2,2-D4) is a deuterated compound of Choline Bromide. Choline Bromide (TYD-01307) has a CAS number of 1927-06-6.

Guanosine-D13 is the deuterated form of Guanosine. Guanosine (T6523) (DL-Guanosine) is a type of nucleoside composed of guanine linked to a ribose ring through a β-N9-glycosidic bond. It exhibits activity against HSV (herpes simplex virus).

MES-D13 is the deuterated form of MES. MES (2-Morpholinoethanesulphonic acid) serves as a zwitterionic buffer with an effective buffering range of pH 5.5-7.0. As a Good's buffer, MES is extensively used in biochemistry and molecular biology experiments, including cell culture, enzyme activity assays, electrophoresis, and protein research.

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-D13 is the deuterated variant of 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (T9510) (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a lipid utilized in liposome synthesis and serves as a lipid component in lipid nanoparticle (LNP) systems.

Choline-D13 chloride is a deuterated form of Choline chloride (T1039). Choline chloride, an organic compound and a quaternary ammonium salt, acts as both a substrate for acyl receptors and choline acetyltransferase. It serves as a photosynthesis enhancer in plants and is also used as a feed additive for poultry and livestock to boost egg and offspring production.

Thymol-D13 is the deuterated analog of Thymol. Thymol (T3S0717) is a major monoterpenol found in essential oils derived from plants belonging to the Lamiaceae family, as well as other families such as Verbenaceae, Scrophulariaceae, and Ranunculaceae. It exhibits antioxidant, anti-inflammatory, antibacterial, and antifungal properties.

Palmitoleic acid-D13 is the deuterated form of Palmitoleic acid (T4872). Palmitoleic acid, a component of fatty acids, has the potential to prevent death from cerebrovascular diseases in SHRSP rats.

Acetylcholine-D13 bromide is the deuterated form of Acetylcholine bromide (T20344).

Adenosine-D13 is a deuterium-labeled form of Adenosine. Adenosine (T0853) (Adenine riboside) is a widely present endogenous secretion that exerts effects via four G-protein-coupled receptors (A1, A2A, A2B, and A3). It influences nearly all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

2'-Deoxyguanosine-D13 is a deuterium-labeled form of 2'-Deoxyguanosine (T22218) (Deoxyguanosine), also known as guanine deoxyriboside.

Lusutrombopag-D13 is a deuterated compound of Lusutrombopag. Lusutrombopag (TQ0223) has a CAS number of 1110766-97-6. Lusutrombopag (TQ0223) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.

Alachlo-D13 (2,6-diethylphenyl-D13) is a deuterated compound of Alachlo.

4-tert-Butylbenzoic acid-d13 (p-tert-Butylbenzoic acid-d13) is the deuterium-labeled form of 4-(tert-Butyl)benzoic acid.

Ethyl heptanoate-d13 is the deuterium-labeled form of ethyl heptanoate. Ethyl heptanoate is commonly utilized as a fragrance component in various products, such as foods, beverages, and personal care items. It also serves as a solvent and a foundational material in synthesizing diverse organic compounds, including pharmaceuticals and agrochemicals. Additionally, the compound's low toxicity and biodegradability have led to research into its potential use as a bio-based solvent, along with investigations into its possible antibacterial properties against certain bacteria and fungi.

5-Phenylvaleric acid-d13 (5-Phenylpentanoic acid-d13) is the deuterium-labeled version of 5-Phenylvaleric acid. This compound, also known as 5-Phenylpentanoic acid, is a primary metabolite produced from flavan-3-ol by intestinal microbiota and can serve as a biomarker for flavan-3-ol intake. Additionally, 5-Phenylvaleric acid is utilized as a precursor for synthesizing polyhydroxyalkanoates.

Bromoxynil-heptanoate-d13 is the deuterium-labeled variant of Bromoxynil-heptanoate.

Methyl heptanoate-d13 (Methyl enanthate-d13) is the deuterium-labeled form of Methyl heptanoate. Commonly used as a flavor and fragrance ingredient in the food and cosmetic industries, Methyl heptanoate also serves as a solvent for various substances, including resins, oils, and waxes. Additionally, its potential applications in biofuel and polymer production have been studied.

9-Bromo-10-phenylanthracene-d13 is a carbon-13 labeled version of 9-Bromo-10-phenylanthracene.

Acetylcholine-[D13] Bromide (N,N,N-Trimethyl-D9; 1,1,2,2-D4) (Standard) is a reference standard of Acetylcholine-[D13] Bromide (N,N,N-Trimethyl-D9; 1,1,2,2-D4) intended for quantitative analysis, quality control, and related biochemical research applications.

Heptanoic-D13 Acid (Standard) is a reference standard of Heptanoic-D13 Acid intended for quantitative analysis, quality control, and related biochemical research applications.

Palmitoleic Acid-D13 (Standard) is a reference standard of Palmitoleic Acid-D13 intended for quantitative analysis, quality control, and related biochemical research applications. Palmitoleic acid-d13 is the deuterated form of Palmitoleic acid. Palmitoleic acid, a component of fatty acids, has the potential to prevent death from cerebrovascular diseases in SHRSP rats.

VVD-130037 is a small molecule activator specifically targeting Kelch-like ECH-associated protein 1 (KEAP1) with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.