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Results for "

corydalis

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    37
    TargetMol | Inhibitors_Agonists
  • Compound Libraries
    1
    TargetMol | Compound_Libraries
  • Natural Products
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Dehydrocorydaline
Dehydrocorydalin, 13-Methylpalmatine
T5S235830045-16-0
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax Bcl-2, activating caspases as well as cleaving PARP.
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L-(R,S)-Tetrahydropalmatine
TETRAHYDROPALMATINE HYDROCHLORIDE
T271410097-84-4
L-(R,S)-Tetrahydropalmatine (Rotundine) is extracted from Corydalis yanhusuo W. T. Wang.
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Bicuculline
d-Bicuculline, (+)-Bicuculline
T2850485-49-4
Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors, originally identified in 1932 from plant alkaloid extracts, and isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and various Corydalis species.
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13-Methylberberine chloride
TN118954260-72-9
13-Methylberberine chloride shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug
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Pseudocoptisine acetate
Isocoptisine acetate
T1257030426-66-5
Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.
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Tetrahydropalmatine
DL-Tetrahydropalmatine, Rotundine
T27932934-97-6
Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic attack in rats.
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Tetrahydroberberine
Tetrahydroberberine THB, Canadine
T2874522-97-4
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
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Tetrahydropalmatine hydrochloride
1-Tetrahydropalmitine HCl, Gindarine hydrochloride
T29176024-85-7
Tetrahydropalmatine hydrochloride (Gindarine hydrochloride) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo). It is a potent muscle relaxant.
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Dehydrocorydaline nitrate
T2S236213005-09-9
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially attributed to DHC. 2. Dehydrocorydal
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7-10 days
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Corydine
T2S2363476-69-7
Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial
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Allocryptopine
Thalictrimine, Fagarine I
T3A2467485-91-6
Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
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Tetrahydrocoptisine
STYLOPINE
T4S20634312-32-7
1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process. 3. Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression. 4. Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1 2 and phospho-p38MAPK signal pathways.
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Stylopine hydrochloride
T580796087-21-7
Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.
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Glaucine
T5S2059475-81-0
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 i
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Acetylcorynoline
O-Acetylcorynoline, (+)-Corynoline Acetate
T5S235718797-80-3
1. Acetylcorynoline (O-Acetylcorynoline) has antifungal,anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.
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Corydaline
Corydalin, (+)-Corydaline
T5S2360518-69-4
1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastric accommodation. 3. Corydaline exhibits the anti-acetylcholinesterase, antiallergic, and antinociceptive activities. 4. Corydaline has potent inhibition of CYP2C19 and CYP2C9.
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Epiberberine
T5S23616873-09-2
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf MEK1 ERK1 2 and AMPKα Akt pathways during 3T3-L1 adipocyte differentiation. 3. Epiberberine, as the brightest FSA emitter among the alkaloids, can also serve as an efficient conformation probe for HTG DNA and discriminate the DNA G-quadruplex from the RNA counterpart.
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Corynoline
(+)-Corynoline
T6S235618797-79-0
1. Corynoline ((+)-Corynoline) is an acetylcholinesterase inhibitor.
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Tetrahydropalmatrubine
T810087762-76-7
Tetrahydropalmatrubine, an alkaloid, is isolated from the herb Corydalis saxicola [1].
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Sibiricine
T8115924181-66-6
Sibiricine (Compound 8), an isoquinoline alkaloid extracted from the medicinal plant Corydalis crispa, exhibits substantial anti-inflammatory effects by inhibiting TNF-α production in LPS-activated THP-1 cells [1].
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Tetrahydroepiberberine
T818738853-67-7
Tetrahydroepiberberine, an isoquinoline alkaloid, has antifungal and selective inhibition against the PI-3 virus activities.
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Dihydroberberine
T8189483-15-8
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interaction with hERG.
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Corycavine
T82680521-87-9
Corycavine, an alkaloid, can be isolated from Corydalis remota [1].
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Pseudocoptisine chloride
Isocoptisine chloride
T986230044-78-1
Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μM).
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