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By Target- Antibacterial
- Endogenous Metabolite(11)
- PROTAC Linker(8)
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By ResearchField- Cancer(16)
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Results for "
composition
" in TargetMol Product Catalog- Inhibitors & Agonists98
- Compound Libraries2
- Peptide Products9
- Inhibitory Antibodies1
- Dye Reagents1
- PROTAC Products10
- Natural Products14
- Reagent Kits14
- Recombinant Protein19
- Isotope Products3
- Disease Modeling1
- Cell Research26
- Reference Standards2
- ADC/ADC Related2
tert-Butyl 11-aminoundecanoate
T18788220851-29-6
tert-Butyl 11-aminoundecanoate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- $29
Size
QTY
MERS-CoV-IN-1
T96142245697-92-9
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus and is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS).
- $41
Size
QTY
Theaflavin digallate
Theaflavine bisgallate, theaflavin digallate, TFBG
T4S055433377-72-9
Theaflavin digallate and lactic acid together could reduce herpes simplex virus transmission.
- $98
Size
QTY
Diazolidinyl urea
Germall II
T812378491-02-8
Diazolidinyl urea (Germall II) is a formaldehyde-releasing preservative used in cosmetics and personal-care products,
- $29
Size
QTY
Miconazole nitrate
R18134 nitrate, NSC 169434 Nitrate
T0344L22832-87-7
Miconazole nitrate (R18134 nitrate), an imidazole antifungal agent, selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes.
- $50
Size
QTY
Diethyltoluamide
N,N-Diethyl-m-toluamide, N,N-Diethyl-meta-toluamide, Delphene, DEET
T0731134-62-3
Diethyltoluamide (DEET) is the most common active ingredient in insect repellents.
- $41
Size
QTY
Butoconazole nitrate
RS 35887
T143864872-77-1
Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butoconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms.
- $33
Size
QTY
Br-C10-methyl ester
T176946287-90-7
Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a linker; notably, one ligand interacts with the VHL portion.
- $29
Size
QTY
Monoethyl pimelate
T1836333018-91-6
Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1].
- $29
Size
QTY
Lecithin
Cited
Phospholutein, Phosphatidylcholines, L-α-Phosphatidylcholine
T32378002-43-5
Lecithin (L-alpha-phosphatidylcholine) is considered a safe source of conventional phospholipids. Phospholipids can change the fatty acid composition and microstructure of animal cell membrane.
- $30
Size
QTY
CitedBetaine Cited
trimethylglycine, oxyneurine, lycine, glycine betaine, Abromine
T3243107-43-7
Betaine (trimethylglycine) is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscle gain and fat loss because of its abilities to promote protein synthesis in the body.
- $33
Size
QTY
CitedElubiol
dichlorophenyl imidazoldioxolan
T3535367914-69-6
Elubiol (dichlorophenyl imidazoldioxolan) is a new broad-spectrum antifungal product of imidazole, which can inhibit the biosynthesis of fungal ergosterol and change the composition of other lipid compounds in the cell membrane. Elubiol is used for skin and hair care in subjects with oily skin or dandruff.
- $29
Size
QTY
1-Stearoyl-rac-glycerol
Monostearin, Glyceryl monostearate
T36454123-94-4
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenesis. 1-Stearoyl-rac-glycerol has been used in the composition of transfersomes for transdermal delivery of doxorubicin in rats, leading to doxorubicin accumulation in lymph nodes, spleen, and heart.
- $30
Size
QTY
DL-Isocitric acid trisodium salt
Isocitric acid trisodium salt
T50871637-73-6
DL-Isocitric acid trisodium salt is the protonated form of isocitrate, a substrate in the citric acid cycle. It is useful as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
- $50
Size
QTY
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol
8-9-epoxy-3-isobutyryloxy-10-2-methylbutanoyl-thymol
T1019722518-07-6
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol, a chemical component of essential oils from Telekia speciosa, exhibits significant antiproliferative activity against human cancer cell lines in vitro.
- $240
Size
QTY
Dazopride
AHR-5531
T1096370181-03-2
Dazopride [LY-237733, AHR-5531] is an antiemetic agent with the chemical composition C15H15N5O2S and a molecular weight of 329.38 g/mol. It appears as white to off-white crystalline powder, melting at 159–162°C, and is soluble in water (forceps method) and organic solvents (chlorinated solvents).
- $1,520
Size
QTY
Retagliptin Phosphate
SP 2086
T127101256756-88-3
Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.
- $30
Size
QTY
Tos-PEG4-t-butyl ester
Tos-PEG4-Boc
T17133217817-01-1
Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2/FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].
- Inquiry Price
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QTY
Boc-Pip-alkyne-Ph-COOH
T17689
Boc-Pip-alkyne-Ph-COOH, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in synthesizing PROTACs including ARD-266. This compound demonstrates significant efficacy in promoting the degradation of androgen receptor (AR) protein across AR-positive prostate cancer cell lines such as LNCaP, VCaP, and 22Rv1, showcasing DC50 values ranging from 0.2-1 nM[1].
- Inquiry Price
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NH2-PEG5-C6-Cl
T184931261238-22-5
NH2-PEG5-C6-Cl (K-7) is a PROTAC linker characterized by its PEG composition. It can be utilized in the synthesis of various PROTACs, facilitating the degradation of intracellular molecules via autophagy[1].
- Inquiry Price
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Phthalimide-PEG4-MPDM-OH
T18543
Phthalimide-PEG4-MPDM-OH, a PROTAC linker with a PEGs composition, has applications in the synthesis of various PROTACs. These PROTACs consist of a linker connecting two distinct ligands: one binds to an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively induce the degradation of target proteins [1].
- Inquiry Price
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S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
s-1-hydroxy-2-methylpropan-2-yl-methanesulfonothioate
T186532127875-65-2
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione-cleavable compound used for attaching monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs), specifically referring to the Alkyl-Chain composition of the linker portion of these molecules [1].
- $77
Size
QTY
DZ-837
T200170
DZ-837 is a PROTAC that targets the BCL6 protein. The composition of DZ-837 includes the BCL6 ligand-2, the E3 ubiquitin ligase ligand Thalidomide-4-OH, and a PROTAC Linker. The configuration notably features a conjugate of the E3 ubiquitin ligase ligand and the Linker, designated as 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-hydroxyethoxy)ethyl)amino)isoindoline-1,3-dione.
- Inquiry Price
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15:0 PG sodium
1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium
T201003322647-32-5
15:0 PG sodium serves as an activator for the Protein Kinase C family and is an anionic phospholipid located in the membranes of mitochondria and microsomes. It plays a crucial role in the composition of pulmonary surfactants, especially within the membrane of the pulmonary lamellar bodies.
- Inquiry Price
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