cinnamic

Cinnamic acid, hydrazide is an unsaturated carboxylic acid and precursor to aspartame via enzyme-catalysed amination to phenylalanine. Cinnamic acid may be useful in prevention or treatment of Diabetes through various mechanism of actions including stimulation of insulin secretion, improvement of pancreatic β-cell functionality, inhibition of hepatic gluconeogenesis, enhanced glucose uptake, increased insulin signaling pathway, delay of carbohydrate digestion and glucose absorption, and inhibition of protein glycation and insulin fibrillation.

trans-Cinnamic acid (Myricitrine) exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.

Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.

p-Hydroxycinnamic acid (NSC-59260) can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.

(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural compound derived from the roots and rhizomes of Notopterygium incisum.

trans-Cinnamic acid (Standard) is a reference standard for research and analysis in studies involving trans-Cinnamic acid. trans-Cinnamic acid (Myricitrine) exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.

1. trans-Cinnamaldehyde (Phenylacrolein) exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor. 2. Cinnamic aldehyde induces apoptosis of CML cells in vitro, down-regulation of the expression and function of BCR-ABL may be one of its most important anti-leukemia mechanisms. 3. Cinnamic aldehyde and cinnamic acid are cardioprotective in a rat model of ischemic myocardial injury, the mechanism is related to anti-oxidative and anti-inflammatory properties.

1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the expression of miR-27a. 4. Cinnamaldehyde induces the generation of reactive oxygen species and exerts vasodilator and anticancer effects. 5. Cinnamaldehyde appears to be a promising candidate as an adjuvant in combination therapy with 5-fluorouracil (5-FU) and oxaliplatin (OXA), two chemotherapeutic agents used in CRC treatment. The possible mechanisms of its action may involve the regulation of drugmetabolizing genes. 6. Cinnamaldehyde plays a certain role in inhibiting the occurrence and progression of melanoma and its action mechanism may be manifested by inhibiting expression of VEGF and HIF-α, thus blood vessel simulation and formation of new blood vessels of melanoma cells, and growth of tumors accordingly.

Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.

Benzyl cinnamate (Benzylcinnamoate) is a natural product isolated from various plant species,with anti-inflammatory activity.

Benzyl cinnamate (Standard) is the standard substance of Benzyl cinnamate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Benzyl cinnamate (Benzylcinnamoate) is a natural product isolated from various plant species,with anti-inflammatory activity.

trans-Cinnamic anhydride is a useful organic compound for research related to life sciences. The catalog number is T125325 and the CAS number is 21947-71-7.

2-(Trifluoromethyl)cinnamic acid is a useful organic compound for research related to life sciences. The catalog number is T64859 and the CAS number is 2062-25-1.

4-(Trifluoromethoxy)cinnamic Acid is a useful organic compound for research related to life sciences. The catalog number is T66196 and the CAS number is 783-13-1.

4-(Trifluoromethyl)cinnamic acid is a useful organic compound for research related to life sciences and the catalog number is T67405.

Cinnamic acid-d6 is the deuterated form of Cinnamic acid. It shows potential applications in cancer treatment, with IC50 values ranging from 1 to 4.5 mM for glioblastoma, melanoma, prostate cancer, and lung cancer cells.

9-O-β-D-Glucopyranosyl-3,4-dimethoxy-cinnamic acid is an orally bioactive phenylpropanoid glycoside identified in Microlepia pilosissima, acting as an antioxidant. It demonstrates DPPH radical scavenging activity with an ED50 value of 38.1 μM. This compound holds potential for research in oxidative stress-related conditions such as inflammation and liver damage.

4-Methylcinnamic acid is a cinnamic acid analog that can be used as an intervention catalyst to overcome antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents.

3-(Trifluoromethyl)cinnamic acid (3-(3-(Trifluoromethyl)phenyl)acrylic acid) can be used to study drug-resistant bacterial infections.

3,5-Dibromo-4-[3-(dimethylamino)propoxy]cinnamic acid is a useful organic compound for research related to life sciences and the catalog number is T126018.

Cinnamic acid, m-chloro-alpha-methyl-, 7-nitro-8-quinolyl ester is a bioactive chemical.

Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) is the 13C labeled variant of cinnamic acid, which is potentially useful in cancer treatment. It has demonstrated IC50 values ranging from 1 to 4.5 mM against glioblastoma, melanoma, prostate, and lung cancer cells.

trans-Cinnamic acid-d7 is the deuterated form of trans-Cinnamic acid. This compound functions as a fungicide with a minimum inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen Aeromonas sobria (A. sobria, SY-AS1).

4-(Dimethylamino)cinnamic acid (DMACA) could be as charge transfer (ICT) probe.