benzimidazole

Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its downstream activity. As a result this agent interferes with mediator release from mast cells either by inhibiting calcium ion influx across mast cell/basophil plasma membrane or by inhibiting intracellular calcium ion release within the cells. In addition, emedastine may also inhibit the late-phase allergic reaction mediated through leukotrienes or prostaglandins, or by producing an anti-platelet activating factor effect. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva. Emedastine does not affect adrenergic, dopamine, or serotonin receptors.

2-(Trifluoromethyl)benzimidazole a novel in vitro and in vivo inducer of iron death with antiparasitic activity.

2-(3-HYDROXYPROPYL)BENZIMIDAZOLE, with CAS No. 2403-66-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).

1H-Benzimidazole-2-methanamine, 6-chloro-, dihydrochloride, with CAS No. 1185297-00-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H-Benzimidazole-2-methanamine, 6-chloro-, dihydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-PYRROLIDIN-2-YL-1H-BENZIMIDAZOLE DIHYDROCHLORIDE, with CAS No. 1049751-43-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-PYRROLIDIN-2-YL-1H-BENZIMIDAZOLE DIHYDROCHLORIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-(2-Hydroxyphenyl)-1H-benzimidazole has been used as a catalyst for the synthesis of polymers and other materials.

2-Hydroxybenzimidazole (2-Benzimidazolinone) is used as an intermediate in industry.

2-AMINO-1-METHYLBENZIMIDAZOLE, with CAS No. 1622-57-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-AMINO-1-METHYLBENZIMIDAZOLE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Benzimidazolebutyricacid,1-methyl-(8CI), with CAS No. 802044-51-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Benzimidazolebutyricacid,1-methyl-(8CI) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Propylbenzimidazole, with CAS No. 5465-29-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Propylbenzimidazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of protein kinase CK2 [1].

1,3-Dimethyl-2-oxobenzimidazole-5-carbaldehyde serves as an intermediate.

1-Methylbenzimidazole is a benzimidazole derivative widely used in biochemical experiments and drug synthesis research.

N-Ethylbenzimidazole exhibits antibacterial activity against Staphylococcus aureus, Escherichia coli, and Aspergillus niger and can be used in related research in the field of life sciences.

5-Methoxy-2-benzimidazolethiol, catalog number T67503 and CAS number 37052-78-1, is a valuable organic compound for life sciences research.

2-Aminobenzimidazole (Standard) is the standard substance of 2-Aminobenzimidazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments.

2-Mercaptobenzimidazole (Standard) is the standard substance of 2-Mercaptobenzimidazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments.

2-Chlorobenzimidazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

5-Difluoromethoxy-2-mercaptobenzimidazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

2-Bromobenzimidazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Tilomisole (Wy 18251) is an orally available benzimidazole thiazole with anti-inflammatory activity and immunomodulatory activity.Tilomisole is used in the study of cancer and inflammation.

TJ08 is a 1,2,5-trisubstituted benzimidazole derivative with anticancer properties that effectively induces G1 S phase blockade while promoting apoptotic effects in a variety of cancer cells.

Chlamydia pneumoniae-IN-1 (compound 55), a benzimidazole derivative, exhibits potent antibacterial activity, inhibiting 99% of C. pneumoniae growth at a concentration of 10 μM while maintaining 95% viability of host cells. It effectively inhibits the CV-6 strain of C. pneumoniae with a minimum inhibitory concentration (MIC) of 12.6 μM, demonstrating its antichlamydial efficacy [1].