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at6

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  • Inhibitors & Agonists
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AT6
T135612098836-50-9
AT6 is a PROTAC AT1 analog which is a highly selective bromodomain (Brd4) degrader.
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SD-436
SD436
T2033952497585-50-7
SD-436 is a selective and highly efficient STAT3 PROTAC degrader (DC50 = 0.5 μM), with an IC50 of 19 nM for STAT3, significantly higher than for STAT1/4/5/6. SD-436 depletes STAT3 and induces tumour regression in mouse leukaemia and lymphoma xenograft models.
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