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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35880 | Renin Fluorogenic Substrate | ||
The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. After cleava... | |||
T38900 | Renin FRET Substrate I | ||
Renin FRET Substrate I is a specific compound that functions as a substrate for human renin. It is specifically designed to contain the exact cleavage site found in the N-terminal peptide of human angiotensinogen. | |||
TP2351 | Renin inhibitory peptide | Pro-his-pro-phe-his-phe-phe-val-tyr-lys | |
Renin inhibitory peptide is an analog of angiotensinogen. | |||
TP2351L | Renin inhibitory peptide, statine | SCRIP,Iva-his-pro-phe-his-sta-leu-phe-NH2 | |
Renin inhibitory peptide, statine is a effective, specific statine-containing renin inhibitor. | |||
T76443 | Renin substrate 1 | ||
Renin substrate 1 is a renin substrate with high affinity to the enzyme [1] . | |||
T62138 | Renin inhibitor-1 | ||
Renin inhibitor-1 (compound 26) is a potent, orally active renin inhibitor capable of acting on rh-renin (IC50: 0.9 nM) and hPRA (IC50: 1.8 nM). renal disease. | |||
T80244 | Renin inhibitor peptide,rat | ||
Renin Inhibitor Peptide, Rat, is a biologically active peptide that functions as a specific inhibitor of rat renin. | |||
T3064 | VTP-27999 | VTP27999 | RAAS |
VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function. | |||
T26127 | R-PEP 27 | Renin inhibitory peptide, R-pep-27,Pro-his-pro-phe-his-statine-ile-phe-NH2 | |
R-PEP 27 is an inhibitor of potent renin, decreased plasma angiotensin II, and blood pressure in normal volunteers. | |||
T7714 | Temocapil | Tyrosinase | |
Temocapril is an inhibitor of tyrosine kinase. | |||
TP1929L1 | Saralasin acetate(34273-10-4 free base) | RAAS | |
Saralasin acetate is a Non-selective angiotensin II antagonist. | |||
T1520 | Aliskiren hemifumarate | CGP 60536,SPP 100,CGP60536B | RAAS , Autophagy |
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity. | |||
T7668 | VTP-27999 TFA | RAAS | |
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM). | |||
T6666 | Sevelamer Carbonate | Others | |
Sevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. | |||
T6698 | Temocapril hydrochloride | CS-622 HCl,Acecol,Temocapril HCl,CS-622 | RAAS |
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension. | |||
T37683 | 3-Hydroxykynurenine | 3-hydroxy-DL-Kynurenine,DL-3-Hydroxykynurenine | Others |
3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%. | |||
T70549 | Kadsurenin L | ||
Kadsurenin L is a neolignan originally isolated from Piper kadsura. It has a role as a platelet-activating factor receptor antagonist and a plant metabolite. | |||
T3011L | Kynurenine sulfate monohydrate | L-Kynurenine sulfate monohydrate | |
Kynurenine sulfate monohydrate is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist agent in the central nervous system. L-Kyn is known to be a pigment genera... | |||
T32361 | Karenin | ||
Karenin is a bioactive chemical. | |||
T72430 | L-Kynurenine sulfate | ||
L-Kynurenine sulfate, an aryl hydrocarbon receptor ( AHR ) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype . | |||
T125390 | Glisoprenin D | ||
Glisoprenin D is a useful organic compound for research related to life sciences. The catalog number is T125390 and the CAS number is 205594-89-4. | |||
T124831 | Scillarenin | ||
Scillarenin is a useful organic compound for research related to life sciences. The catalog number is T124831 and the CAS number is 465-22-5. | |||
T34194 | Puntarenine | ||
Puntarenine is an alkaloid of the isohomoprotoberberine family that has shown marginal activity against the dermatophytic fungus Trichophyton mentagrophytes and the yeast Saccharomyces cerevisiae. | |||
T71760 | 4-Chlorokynurenine | ||
4-Chlorokynurenine is a prodrug of 7-Cl-kynurenic acid (7-Cl-KYNA), a potent, selective antagonist of the NMDA/glycine receptor. | |||
T4313 | Tinoridine hydrochloride | Nonflamin,Y-3642 hydrochloride | COX , Glutathione Peroxidase |
Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid... | |||
T28950 | Terlakiren | CP 80794,CP-80,794 | RAAS |
Terlakiren (CP-80,794) is an orally active and potent renin inhibitor that inhibits the potency of human renin for the study of neurological disorders of the hypertension class. | |||
TP1842L | Angiotensinogen (1-14), human acetate | Endogenous Metabolite | |
Angiotensinogen (1-14), human acetate is a fragment of angiotensinogen which is a passive substrate of the renin-angiotensin system. | |||
T3695 | Pepstatin | Pepstatin A,Pepsin Inhibitor S 735A,Ahpatinin C | Amino Acids and Derivatives , Proteasome , HIV Protease , Autophagy |
Pepstatin (Pepsin Inhibitor S 735A) is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin. | |||
T37496L | Alamandine TFA | RAAS | |
Alamandine TFA , a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine TFA targets to protect the kidney and heart through anti-h... | |||
T2639 | LY2811376 | Beta Amyloid , Beta-Secretase , BACE | |
LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition... | |||
TP1295 | Angiotensin I (human, mouse, rat) | Angiotensin 1 Human | Others |
Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an in... | |||
T22574L | Angiotensin 1/2 (5-7) acetate | RAAS | |
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum... | |||
T14123 | ACT 178882 | RAAS | |
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM). | |||
T19187 | Aliskiren D6 hemifumarate | CGP 60536 D6 hemifumarate,SPP 100 D6 hemifumarate,CGP60536B D6 hemifumarate | RAAS |
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM). | |||
T30829 | Cgp 38560 | Cgp38560,Cgp-38560 | |
CGP 38560 is a potent renin inhibitor. | |||
T24284 | L 363564 | L-363,564,L-363564,L363,564,L363564,L 363,564 | |
L 363564 is a kidney renin inhibitor. | |||
T31033 | CP 81282 | CP81282,CP-81,282,CP-81282 | |
CP 81282 inhibits human renin and endothiapepsin. | |||
T25345 | Ditekiren | U 71038,U71038,U-71038,Ditekirenum | |
Ditekiren is a renin inhibitor with orally active. | |||
T38672 | VTP-27999 Hydrochloride | ||
VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases. IC50 value: Target: Renin | |||
T26439 | A 74273 | A-74273,A74273 | |
A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition. | |||
T25479 | H 142 | H142,H-142 | |
H 142 is a human renin decapeptide inhibitor. | |||
T25368 | Emd 51921 | Emd51921,Emd-51921,Emd-51,921,Emd 51,921,Emd 51 921 | |
Emd 51921 is a linear peptide renin inhibitor. | |||
T25370 | Emd 55068 | Emd-55068,Emd55068 | |
Emd 55068 is a synthetic antagonist of renin. | |||
T26215 | SQ 30774 | SQ-30774,SQ 30,774,SQ30774,SQ30,774,SQ-30,774 | |
SQ 30774 is a representative of the imidazole alcohols-a novel class of renin inhibitors. | |||
T25386 | ES 6864 | ES-6864,ES6864 | |
ES 6864 is an orally active inhibitor of renin. | |||
T30921 | CI 992 | CI-992,CI992 | |
CI 992 is a novel potent inhibitor of primate renin. | |||
T26431 | A 65317 | A-65317,A65317 | |
A 65317 is a selective renin inhibitor that causes a blockade of the renin-angiotensin system. | |||
T29204 | Zankiren | A72517,A-72517,A 72617 | |
Zankiren is a renin inhibitor. Zankiren can reduce blood pressure, plasma renin activity, and angiotension II. | |||
T71318 | H 218-54 | ||
H 218-54 is a renin inhibitor. | |||
T26307 | U 77436 | U-77436,U77436 | |
U 77436 is a renin inhibitory peptide. |
Cat No. | Product Name | Synonyms | Targets |
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T4S0290 | Araloside A | Chikusetsusaponin IV | RAAS , Fas/FasL |
Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway. | |||
T4928 | L-Kynurenine | (S)-Kynurenine | AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite |
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ... | |||
T10938 | D-Kynurenine | (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 | GPR , AhR , Endogenous Metabolite |
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluor... | |||
TN6778 | Umbelliprenin | 7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin | IL Receptor |
Umbelliprenin (7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin) alleviated neuropathic pain, and decreased serum IL-6 levels and oxidative stress. | |||
T79948 | Kadsurenin B | ||
Kadsurenin B, a platelet-activating factor (PAF) antagonist, exhibits neuroprotective properties and has a broad spectrum of pharmacological research applications, including antibacterial, anti-inflammatory, neuroprotect... | |||
TN4365 | Kadsurenin D | Others | |
Kadsurenin D is a natural product for research related to life sciences. The catalog number is TN4365 and the CAS number is 140669-89-2. | |||
TN3055 | 4-O-Demethylkadsurenin D | Others | |
4-O-Demethylkadsurenin D is a natural product for research related to life sciences. The catalog number is TN3055 and the CAS number is 127179-70-8. | |||
T2S1727 | Lycorenine | Antifection | |
Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic nerve activity, and produce bradycardia by modifying vagal a... | |||
T81994 | Kadsurenin A | ||
Kadsurenin A is a bioactive lignan derived from the Piper genus. | |||
T3S0804 | Worenine | Worenin | Others |
Worenine (Worenin) is used in the a flurophore switched probe which aids in correction of an abasic site (AP site) caused by the removal of a damaged base in DNA. | |||
TN4302 | Isokadsurenin D | Others | |
Isokadsurenin D is a natural product of Kadsura, Schisandraceae. The catalog number is TN4302 and the CAS number is 147976-35-0. Isokadsurenin D can be used as a reference standard. | |||
TN3054 | 4-O-Demethylisokadsurenin D | Others | |
4-O-Demethylisokadsurenin D is a natural product for research related to life sciences. The catalog number is TN3054 and the CAS number is 89104-59-6. | |||
T0522 | Diammonium Glycyrrhizinate | Glycyrrhizin | Dehydrogenase |
Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and ... | |||
T38649 | Lyciumin A | ||
Lyciumin A, a cyclic octapeptide, possesses inhibitory properties against proteases, renin, and angiotensin-converting enzyme. It holds potential for hypertension research. | |||
T19186 | Aldosterone | Others | |
Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00908 | Renin Protein, Human, Recombinant (His) | Human | HEK293 |
Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sod... | |||
TMPY-05808 | Renin Protein, Human, Recombinant (R66K, His) | Human | HEK293 |
Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sod... | |||
TMPY-01231 | Renin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sod... | |||
TMPH-02881 | Renin-2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
TMPH-02023 | Renin receptor Protein, Human, Recombinant (His) | Human | E. coli |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra... | |||
TMPY-02418 | Kynureninase/KYNU Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranili... | |||
TMPY-02479 | Kynureninase/KYNU Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranili... | |||
TMPH-03021 | PstP Protein, Mycobacterium tuberculosis, Recombinant (His) | Mycobacterium tuberculosis | E. coli |
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role ... | |||
TMPH-02592 | CTHRC1 Protein, Mouse, Recombinant (aa 33-245, His) | Mouse | HEK293 |
Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood... | |||
TMPY-02232 | Angiotensinogen Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti... | |||
TMPY-01232 | Angiotensinogen Protein, Human, Recombinant (His) | Human | HEK293 |
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti... | |||
TMPY-02896 | Aminopeptidase A Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
ENPEP, also known as aminopeptidase A, is a member of the peptidase M1 family. Members of this family are involved in response to cadmium ion and proteolysis. They located in 6 components and are expressed in 26 plant st... | |||
TMPY-04501 | Angiotensinogen Protein, Rat, Recombinant (His) | Rat | HEK293 |
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti... | |||
TMPY-00644 | Aminopeptidase A Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
ENPEP, also known as aminopeptidase A, is a member of the peptidase M1 family. Members of this family are involved in response to cadmium ion and proteolysis. They located in 6 components and are expressed in 26 plant st... | |||
TMPY-03041 | Aminopeptidase A Protein, Rat, Recombinant (aa 41-945, His) | Rat | Baculovirus-Insect Cells |
ENPEP, also known as aminopeptidase A, is a member of the peptidase M1 family. Members of this family are involved in response to cadmium ion and proteolysis. They located in 6 components and are expressed in 26 plant st... | |||
TMPY-01635 | PCSK1 Protein, Human, Recombinant (His) | Human | HEK293 |
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the... | |||
TMPH-01615 | OPN1LW Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are a... | |||
TMPH-01616 | LRP2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are a... | |||
TMPY-01839 | ACE2/ACEH Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-04312 | ACE2/ACEH Protein, Human, Recombinant (mFc) | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-01838 | ACE2/ACEH Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-05696 | ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-06334 | ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-05266 | ACE2/ACEH Protein, Human, Recombinant (His) | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-00655 | ACE2/ACEH Protein, Human, Recombinant (hFc) | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-05725 | ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Baculovirus-Insect Cells |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-02207 | ACE2/ACEH Protein, Rat, Recombinant (His) | Rat | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-03830 | ACE2/ACEH Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-03561 | ACE2/ACEH Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... |