3b-hydroxy-8,24-lanostadiene

Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.

Lanosterol-D6 (Standard) is a reference standard of Lanosterol-D6 intended for quantitative analysis, quality control, and related biochemical research applications. Lanosterol-d6 is the deuterated form of Lanosterol. Lanosterol acts as an intermediate in the biosynthesis of cholesterol and can induce the ubiquitination and degradation of HMG-CoA reductase, the rate-controlling enzyme in cholesterol synthesis. Additionally, Lanosterol inhibits the aggregation and cytotoxicity of misfolded proteins linked to neurodegenerative diseases.

Lanosterol-D6 is the deuterated form of Lanosterol. Lanosterol (T4970) acts as an intermediate in the biosynthesis of cholesterol and can induce the ubiquitination and degradation of HMG-CoA reductase, the rate-controlling enzyme in cholesterol synthesis. Additionally, Lanosterol (T4970) inhibits the aggregation and cytotoxicity of misfolded proteins linked to neurodegenerative diseases.

Lanosterol (Standard) is the analytical standard of Lanosterol, primarily used for quantitative analysis and metabolic research. Lanosterol is the first sterol intermediate in the cholesterol biosynthetic pathway, synthesized from squalene via squalene epoxidase. It plays a pivotal role in lipid homeostasis by inducing the ubiquitination and proteasomal degradation of HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the pathway. Beyond its metabolic function, Lanosterol exhibits potent molecular chaperone-like activity, inhibiting the aggregation and associated cytotoxicity of misfolded proteins linked to neurodegenerative diseases and cataracts.