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Kidney Stone Modeling

Kidney stones are a common urinary system disorder, typically formed by the deposition of crystals such as calcium oxalate or calcium phosphate. Common modeling methods include ethylene glycol drinking water and excessive vitamin D administration. These models are used to study stone formation mechanisms, renal tubular injury, and the development of litholytic drugs.

Vitamin D3
T113567-97-0
Vitamin D3 (Cholecalciferol) is a naturally occurring form of vitamin D that, after metabolic activation, can induce cell differentiation and cancer cell proliferation. It can also be used to establish kidney stone models.
  • $33
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Calcium chloride
T6467910043-52-4
Calcium chloride is often used in cell culture research, such as as a calcium supplement in DMEM medium, and can also be used to prepare synthetic saline solutions.
  • $29
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Ammonium chloride
T6475512125-02-9
Ammonium chloride is a compound commonly used in molecular biology research. As a dipolar compound that regulates pH, it can induce intracellular alkalinization and metabolic acidosis, thereby affecting enzyme activity and biological processes. Additionally, ammonium chloride acts as an inhibitor of autophagy and lysosomal function, and can be used to establish kidney stone models.
  • $30
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Glyfosfin
T21306107-22-2
Glyfosfin is a DNA cross-linking and alkylating agent with anticancer activity and can also be used to induce kidney stone models.
  • $1,520
6-8 weeks
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