Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I II (IC50=0.8 2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.

Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates ferroptosis and induces autophagy.

Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA RNA and for the production and maintenance of new cells. Folic acid deficiency can lead to anemia, neural tube closure defects, tumors, aging, and other diseases.

Adenine (6-Aminopurine), a purine derivative, is a nucleobase essential in biochemistry, participating in cellular respiration through ATP, NAD, and FAD, and in protein synthesis as a component of DNA and RNA.

Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.

Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.

Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.