Overactive Bladder Modeling

Overactive Bladder (OAB) is characterized by symptoms such as increased urinary frequency, urgency, and nocturia. Common modeling strategies include denervation approaches (e.g., sympathetic or parasympathetic nerve removal), low-dose long-term cyclophosphamide stimulation, and urethral obstruction. These models are used to study neural regulation of the urinary system and drug responsiveness.