AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

Cat. No.	Product name	CAS No.	Purity
T61969	AChE/BChE-IN-10		98%
T61969	AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barri...
T62360	AChE-IN-26		98%
T62360	AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor (IC50: 0.42 μM).
T60739L	Y13g dihydrochloride	T60739L	98%
T60739L	Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are rela...
T60891	AChE/BChE/MAO-B-IN-1	2416910-82-0	98%
T60891	AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects o...
T77560	2-Amino-4-(4-chlorophenyl)thiazole	2103-99-3	98%
T77560	2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE is a 2-aminothiazole derivative. 2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE inhibited hCA I, hCA II, AChE and BChE with Ki values of 0...
T68084	Icopezil	145508-78-7	98%
T68084	Icopezil is a small molecule acetylcholinesterase in (AChE) inhibitor for the treatment of neurological disorders and can be used in the study of Alzheimer's dis...
T32535	Ladostigil	209394-27-4	98%
T32535	Ladostigil is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with inhibitory effects on MAO-B and AChE, with IC50 ...
TN2217	Sophoflavescenol	216450-65-6	98%
TN2217	Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , the...
T13446	(S)-Rivastigmine D6 tartrate	194930-00-2	98%
T13446	(R)-Rivastigmine D6 tartrate is the deuterium labeled (R)-Rivastigmine, and is an inhibitor of cholinesterase.
T15949	Mahanimbine	21104-28-9	98%
T15949	Mahanimbine is found in the roots, leaves and stems of Murraya koenigii and is an orally active alkaloid extracted from Murraya koenigii. Bifidobacterium bifidum...
T14194	β-NETA	31059-54-8	98%
T14194	α-NETA is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (...
TN2131	Questin	3774-64-9	98%
TN2131	Questin is an antimicrobial agent derived from Aspergillus florescens with an antimicrobial activity profile that inhibits V. harveyi, V. anguillarum, V. cholera...
T8306	Epiberberine chloride	889665-86-5	98%
T8306	Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor (IC50s: 1.07...
TN1858	Leptomerine	22048-97-1	98%
TN1858	Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.
T2227	Hemicholinium 3	312-45-8	98%
T2227	Hemicholinium-3 is a potent and selective choline uptake blocker.
T3819	Ursolic acid acetate	7372-30-7	98%
T3819	Acetylursolic acid has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities...
TN1124	Neoeriocitrin	13241-32-2	98%
TN1124	Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a...
T0998	Diazinon	333-41-5	98%
T0998	Diazinon is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety of pests includ...
T6478	Donepezil Hydrochloride	120011-70-3	98%
T6478	Donepezil is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).
T2191	Tacrine hydrochloride (hydrate)	206658-92-6	98%
T2191	Tacrine hydrochloride hydrate is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxant...