zanthoxylum

Ombuin has anti-inflammary activity, it inhibits some macrophage functions involved in the inflammatory process.

Xanthoxylin (Xanthoxyline) is a borneol and camphor tasting compound and can be found in a number of food items such as fats and oils, herbs and spices, pomegranate, and sweet orange. Derivatives of Xanthoxylin have antispasmodic activity.

L-Citronellol ((S)-(-)-beta-Citronellol) is a small molecule compound isolated from geranium with antifungal activity, affecting fungal membranes.L-Citronellol acts synergistically with amphotericin B against Candida yeast.

Methyl (E)-cinnamate exhibits antifungal and antibacterial activity, inhibiting Staphylococcus aureus, Salmonella, Penicillium, Fusarium, and other microorganisms, and is widely used in biochemical experiments and drug synthesis research.

Hydroxy-Epsilon-Sanshool is an alkyl amide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensation.

Sanshool is a natural product isolated from Zanthoxylum bungeanum. Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy.

Sanshodiol is a natural product of Zanthoxylum, Rutaceae. The catalog number is T3833 and the CAS number is 54854-91-0. Sanshodiol can be used as a reference standard.

Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a concentration of 100 μM.3 Dietary administration of collinin (0.05% w/w) reduces the number of mice with tumors and the number of tumors per mouse in a mouse model of colitis-related carcinogenesis.4 |1. Kim, S., Seo, H., Al Mahmud, H., et al. In vitro activity of collinin isolated from the leaves of Zanthoxylum schinifolium against multidrug- and extensively drug-resistant Mycobacterium tuberculosis. Phytomedicine 46, 104-110 (2018).|2. Nguyen, P.-H., Zhao, B.T., Kim, O., et al. Anti-inflammatory terpenylated coumarins from the leaves of Zanthoxylum schinifolium with α-glucosidase inhibitory activity. J. Nat. Med. 70(2), 276-281 (2016).|3. I.S., C., Lin, Y.C., Tsai, I.L., et al. Coumarins and anti-platelet aggregation constituents from Zanthoxylum schinifolium. Phytochemistry 39(5), 1091-1097 (1995).|4. Kohno, H., Suzuki, R., Curini, M., et al. Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice. Int. J. Cancer 118(12), 2936-2942 (2006).

1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC.

(-)-Asarinin (Eleutheroside B4) shows antibacterial activity.

Angoline hydrochloride (6-Methoxyldihydrochelerythrine) is an IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum with anticancer activity and inhibits STAT3 signaling.

Dihydronitidine, an alkaloid, can be extracted from Zanthoxylum rhoifolium [1].

Hydroxy-α-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).

Nitidine is a bioactive plant benzophenanthridine alkaloid isolated from the root of Zanthoxylum nitidum. It shows anticancer, neuroprotective, antimalarial, anti-HIV, analgesic, anti-inflammatory and antifungal activities.

Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells.

2-Phenyl-2-propanol (Standard) is a reference standard for 2-Phenyl-2-propanol, suitable for quantitative analysis, quality control, and biochemical experiments. 2-Phenyl-2-propanol is an alcohol and aromatic compound used in the synthesis of diisopropylbenzene peroxide.

Nitidine chloride (Standard) is a reference standard for research and analysis in studies involving Nitidine chloride. 1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC.

Hydroxy-β-sanshool (Standard) is a reference standard for research and analysis in studies involving Hydroxy-β-sanshool. Hydroxy-β-sanshool is a pungent compound obtained from Zanthoxylum piperitum.

Hydroxy-β-sanshool is a pungent compound obtained from Zanthoxylum piperitum.

Hydroxy-γ-sanshool is a pungent compound, it can cause oral numbness.

5,7-Dimethoxyflavanone exhibits µM-level inhibition against MCF-7 and NCI-H187 cells (IC50=36 µM), suitable for biochemical experiments and drug synthesis research.

9-Ethoxychelerythrine serves as a chemical reference standard for the quality control of traditional Chinese herbal medicines derived from species such as Zanthoxylum nitidum. Beyond its analytical applications, emerging studies indicate that this compound may exert notable biological effects, including the ability to induce mitochondrial apoptosis in colorectal cancer cells. This mechanistic insight highlights its potential value as a preliminary lead structure for oncology research, particularly in investigations focused on programmed cell death pathways and natural-product-based anticancer agents.

gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)-inducing activity

Schinifoline is a quinolone derivative extracted from Zanthoxylum schinifolium Sieb with cytotoxic activity that promotes radiosensitization of cancer cells, affects the cell cycle and apoptosis.