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Results for "

zanthoxylum

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    37
    TargetMol | Inhibitors_Agonists
  • Natural Products
    37
    TargetMol | Natural_Products
Xanthoxylin
Xanthoxyline, 2'-Hydroxy-4',6'-dimethoxyacetophenone
T298190-24-4
Xanthoxylin (Xanthoxyline) is a borneol and camphor tasting compound and can be found in a number of food items such as fats and oils, herbs and spices, pomegranate, and sweet orange. Derivatives of Xanthoxylin have antispasmodic activity.
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L-Citronellol
(S)-(-)-β-Citronellol, (S)-(-)-beta-Citronellol
TN49317540-51-4
L-Citronellol ((S)-(-)-beta-Citronellol) is a small molecule compound isolated from geranium with antifungal activity, affecting fungal membranes.L-Citronellol acts synergistically with amphotericin B against Candida yeast.
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NITIDINE
T88596872-57-7
Nitidine is a bioactive plant benzophenanthridine alkaloid isolated from the root of Zanthoxylum nitidum. It shows anticancer, neuroprotective, antimalarial, anti-HIV, analgesic, anti-inflammatory and antifungal activities.
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Hydroxy-Epsilon-Sanshool
T13732252193-26-3
Hydroxy-Epsilon-Sanshool is an alkyl amide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensation.
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Sanshool
T19557504-97-2
Sanshool is a natural product isolated from Zanthoxylum bungeanum. Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy.
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Sanshodiol
T383354854-91-0
Sanshodiol is a natural product of Zanthoxylum, Rutaceae. The catalog number is T3833 and the CAS number is 54854-91-0. Sanshodiol can be used as a reference standard.
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Collinin
T3833034465-83-3
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a concentration of 100 μM.3 Dietary administration of collinin (0.05% w/w) reduces the number of mice with tumors and the number of tumors per mouse in a mouse model of colitis-related carcinogenesis.4 |1. Kim, S., Seo, H., Al Mahmud, H., et al. In vitro activity of collinin isolated from the leaves of Zanthoxylum schinifolium against multidrug- and extensively drug-resistant Mycobacterium tuberculosis. Phytomedicine 46, 104-110 (2018).|2. Nguyen, P.-H., Zhao, B.T., Kim, O., et al. Anti-inflammatory terpenylated coumarins from the leaves of Zanthoxylum schinifolium with α-glucosidase inhibitory activity. J. Nat. Med. 70(2), 276-281 (2016).|3. I.S., C., Lin, Y.C., Tsai, I.L., et al. Coumarins and anti-platelet aggregation constituents from Zanthoxylum schinifolium. Phytochemistry 39(5), 1091-1097 (1995).|4. Kohno, H., Suzuki, R., Curini, M., et al. Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice. Int. J. Cancer 118(12), 2936-2942 (2006).
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Nitidine chloride
T5S076113063-04-2
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC.
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(-)-Asarinin
Pseudocubebin, Episesamin, Asarinin, Sesamin, Eleutheroside B4
T5S1959133-04-0
(-)-Asarinin (Eleutheroside B4) shows antibacterial activity.
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Angoline hydrochloride
6-Methoxyldihydrochelerythrine
T756721071676-04-4
Angoline hydrochloride (6-Methoxyldihydrochelerythrine) is an IL-6 STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum with anticancer activity and inhibits STAT3 signaling.
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Dihydronitidine
T8255313063-06-4
Dihydronitidine, an alkaloid, can be extracted from Zanthoxylum rhoifolium [1].
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Hydroxy-α-sanshool
Hydroxy-​α-​sanshool
T830783883-10-7
Hydroxy-α-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).
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Haplopine
TC00175876-17-5
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells.
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7-10 days
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Hydroxy-β-sanshool
Hydroxy-beta-sanshool
TN108997465-69-5
Hydroxy-β-sanshool is a pungent compound obtained from Zanthoxylum piperitum.
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Hydroxy-γ-sanshool
Hydroxy-gamma-sanshool
TN109078886-66-5
Hydroxy-γ-sanshool is a pungent compound, it can cause oral numbness.
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2-4 weeks
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γ-Fagarine
gamma-Fagarine
TN1138524-15-2
gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug ml, respectively. It has sister chromatid exchanges (SCEs)-inducing activity
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Schinifoline
TN117480554-58-1
Schinifoline is a quinolone derivative extracted from Zanthoxylum schinifolium Sieb with cytotoxic activity that promotes radiosensitization of cancer cells, affects the cell cycle and apoptosis.
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Decarine
TN155654354-62-0
Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP CB-induced elastase release with IC(50) values < or = 5.53 microg mL.
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Kobusin
TN183436150-23-9
Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1 CaCC-mediated short-circuit currents in ANO1 CaCC-expressing FRT cells.
    7-10 days
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    Ombuin
    TN2010529-40-8
    Ombuin has anti-inflammary activity, it inhibits some macrophage functions involved in the inflammatory process.
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    Robustine
    TN21592255-50-7
    Robustine is a natural product, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.
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    Evofolin B
    TN24081961305-60-1
    Evofolin B is a natural compound isolated from the stem bark of Zanthoxylum ailanthoides. Evofolin B has an inhibitory effect on the superoxide anion produced by human neutrophils in response to formyl-L-methionine-L-leucine-L-phenylalanine cytochalasin B (fMLP CB).
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    2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide
    TN2692137809-97-3
    2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide is a natural product (catalog number TN2692, CAS number 137809-97-3) used in life sciences research.
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    4-Methoxy-1-methylquinolin-2-one
    TN304732262-18-3
    4-Methoxy-1-methylquinolin-2-one is a natural product from Zanthoxylum nitidum.
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