tempo

Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.

Acid-PEG5-TEMPO is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, and facilitates selective protein degradation using the ubiquitin-proteasome system within cells.

Mito-TEMPO, a mitochondria-targeted superoxide dismutase mimetic, scavenges superoxide and alkyl radicals, preventing mitochondrial oxidation, necrosis, and apoptosis.

4-carboxy TEMPO is a nitroxide and spin label. Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo., It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.

N3-TEMPO is an azide-functionalized TEMPO spin label. It is used for bioorthogonal labeling via click chemistry and EPR spectroscopy to investigate protein and nucleic acid dynamics.

4-palmitamido TEMPO is a lipid-soluble spin label that integrates into vesicles and cell membranes. It is utilized to examine the encapsulation of molecules within phosphatidylcholine vesicles.

4-Amino-TEMPO is employed as a spin label to detect free radicals and the damage they cause. It mimics the activity of superoxide dismutase and can easily penetrate cells, thus safeguarding them against oxidative damage induced by H2O2. Moreover, 4-Amino-TEMPO demonstrates significant radioprotective properties, effectively shielding DNA from oxidative stress damage caused by UV irradiation by maintaining a positive charge. Additionally, 4-Amino-TEMPO serves as a highly selective oxidation catalyst and is extensively used in the development of various specialty chemicals, including fragrances and pesticides.

Tempone is an aminooxyalkane that acts as a free radical scavenger and reacts with reactive oxygen species (ROS). Intravenous Tempone reduces mean arterial pressure in spontaneously hypertensive rats.

Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.

4-isocyanato TEMPO can be used in related research in the field of life sciences. Its product number is T35644 and CAS number is 88418-69-3.

MitoTEMPO hydrate is a mitochondria-targeted antioxidant and superoxide scavenger. It mimics SOD activity to protect against mitochondrial oxidative stress in hypertension and neurodegeneration research.

Temporin B acetate is an antimicrobial peptide effective against Gram-positive bacteria, exhibiting lower activity against Gram-negative bacteria.

Tempoacmcta is a peptide.

MitoTEMPOL is a mitochondria-targeted antioxidant that prevents septal dysfunction by reversing sepsis-induced decreases in mitochondrial function, activation of protein hydrolysis pathways, and reductions in myosin heavy chain content, as well as eliminating cytokine-induced increases in muscle cell superoxide production and decreases in cell size.

Temporin A, a short alpha-helical antimicrobial peptide derived from the skin of Rana temporaria, exhibits a wide-ranging efficacy against Gram-positive bacteria. It directly interacts with the cell membrane of microorganisms and remains non-toxic to erythrocytes at antimicrobial concentrations. Additionally, Temporin A demonstrates antifungal properties against yeast-like Candida albicans.

Temporin A acetate is a natural short α-helical antimicrobial peptide that targets microbial cell membranes and exhibits inhibitory effects against a broad spectrum of Gram-positive bacteria and fungi.

Temporin L, a potent antimicrobial peptide, exhibits activity against Gram-negative bacteria and yeast strains, as well as demonstrating antiendotoxin properties.

Temporin B, an antimicrobial peptide, is effective against Legionella pneumophila [1].

Temporin C is an antimicrobial peptide effective against *Legionella pneumophila* [1].

Temporin F exhibits antimicrobial activity against Legionella pneumophila [1].

Temporin G, an antimicrobial peptide, exhibits activity against Legionella pneumophila [1].

Temporin K, an antimicrobial peptide, exhibits effectiveness against Legionella pneumophila [1].

Tempol-D17,15N is a superoxide dismutase (SOD) mimic that effectively neutralizes reactive oxygen species (ROS).

Tempol-D17 is the deuterated form of Tempol. Tempol (T6699) functions as a superoxide dismutase (SOD) analog and is effective in neutralizing reactive oxygen species (ROS).