Search Result

Search Results for " pathogenesis "

Targets

Compounds

Natural Products

302

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T9189	Iptacopan hydrochloride	Iptacopan HCl,LNP023 hydrochloride	Complement System
	Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b...		Complement System
T40276	GS-621763		SARS-CoV
	GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis.		SARS-CoV
T19508	Peroxidase		Others
	Peroxidase, found in the roots of horseradish, actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis, and pathogenesis of several diseases.		Others
TP1359L	Amyloid β Peptide (42-1)(human) acetate	Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)	Beta Amyloid
	Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42). Amyloid β Peptide (42-1)(human) acetate is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease...		Beta Amyloid
T40109	APOL1-IN-1	APOL1-IN-1	Others
	APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into thes...		Others
T1993	J-147	J147	Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
	J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T69441	NSC66098
	NSC66098 is a novel potent inhibitor of Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein.
TP1359	β-Amyloid (42-1), human	Amyloid β Peptide (42-1)(human)
	Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
T36638	[Des-His1,Glu9]-Glucagon amide TFA	[Des-His1,Glu9]-Glucagon amide TFA
	[Des-His1,Glu9]-Glucagon amide TFA is a potent peptide antagonist targeting the glucagon receptor, featuring a pA2 value of 7.2. It holds potential utility in diabetes pathogenesis research[1].
TP1390	CEP dipeptide 1
	CEP dipeptide 1, a potent angiogenic compound, exhibits robust activity in promoting angiogenesis. This compound is specifically implicated in the pathogenesis of age-related macular degeneration (AMD).
T32392	Sonlicromanol	KH-176,KH 176,KH176
	KH-176 is an effective intracellular REDOX regulator that targets reactive oxygen species, which are important in the pathogenesis of mitochondrial oxidative phosphorylation disorders and may be used to treat mitochondri...
T76464	FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
	FITC-β-Ala-Amyloid β-Protein (1-42) ammonium, a fluorescein isothiocyanate (FITC)-tagged monomer peptide of Aβ1-42, is instrumental in Alzheimer’s disease pathogenesis [1].
T61064	NAChR antagonist 1
	nAChR antagonist 1 (compound B15) is a highly effective antagonist of α7 nAChR, demonstrating an IC50 value of 3.3 μM. Its versatility makes it an ideal candidate for investigating the pathogenesis of schizophrenia, Alzh...
TP1007	β-Amyloid (1-42), human	β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human	Beta Amyloid
	Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.		Beta Amyloid
T38521	Patamostat mesylate	E-3123 mesylate
	Patamostat mesylate (E-3123) is a highly potent protease inhibitor, displaying strong inhibitory activity against trypsin, plasmin, and thrombin, with IC 50 values of 39 nM, 950 nM, and 1.9 μM, respectively. This compoun...
T69830	GSK2239633
	GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2...
T76797	Anti-Human IL-17A
	Anti-Human IL-17A is a fully human anti- interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis [1] .
T82297	GluN1(356-385)
	GluN1 (356-385) is an antigenic peptide implicated in N-methyl-D-aspartate receptor (NMDAR) encephalitis and has been shown to decrease the density of NMDAR surface clusters in hippocampal neurons. It serves as a tool to...
T36097	TNF-α-IN-2
	TNF-α-IN-2 is a highly potent and orally bioavailable inhibitor of tumor necrosis factor alpha (TNFα), exhibiting an IC50 of 25 nM in the HTRF assay. It exerts its inhibitory effects by inducing conformational changes in...
T81725	Mz325		HDAC
	Mz325 serves as a dual inhibitor of both HDAC and Sirt2, exhibiting an IC50 of 9.7 µM against Sirt2, which are implicated in the pathogenesis of cancer and neurodegenerative diseases [1].		HDAC
T80700	β Amyloid(17-28) human
	β-Amyloid(17-28) human is a fragment of the β-amyloid peptide (Abeta) associated with Alzheimer's disease (AD), promoting the aggregation of the full-length β-Amyloid40 into toxic aggregates [1]. This lipid-induced amylo...
T40043	RORγt Inverse agonist 10
	RORγt Inverse agonist 10 is a highly potent and orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectivel...
T82260	Grisnilimab	WT1
	"Grisnilimab (WT1), an IgG2a monoclonal antibody targeting CD7, acts as a tumor suppressor in the pathogenesis of Wilms' tumor. It modulates the transcription of various genes and may be involved in post-transcriptional ...
T80035	Biotin-β-Amyloid (1-42), human TFA	Biotin-amyloid β-peptide (1-42) (human) TFA
	Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the pathogenesis of Alzheimer's disease [1].
T83557	(3S,4S)-Tivantinib	ARQ 198,(3S,4S)-ARQ 197
	(3S,4S)-Tivantinib, a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET, targets GSK3α and GSK3β—two novel enzymes implicated in the pathogenesis of non-small cell lung cancer (NSCLC) [1].
T9670	Patamostat
	Patamostat (E-3123) is a potent protease inhibitor that effectively inhibits trypsin, plasmin, and thrombin, exhibiting IC50 values of 39 nM, 950 nM, and 1.9 µM, respectively. Research suggests that Patamostat might supp...
T61394	Neuraminidase-IN-5
	Neuraminidase-IN-5 (Compound 5b), a dihydrofurocoumarin derivative, acts as a potent neuraminidase (NA) inhibitor, exhibiting significant inhibition with an IC 50 of 0.02 μM. Given NA's role in influenza pathogenesis, th...
T78344	Pectinase
	Pectinase, a complex of enzymes, catalyzes the hydrolysis of pectic substances and is predominantly found in microorganisms and higher plants. This enzyme plays a crucial role in cell wall metabolism, cell growth, senesc...
T78370	Myelin Basic Protein(87-99) TFA
	Myelin Basic Protein(87-99) TFA, an encephalitogenic peptide, promotes basic protein-specific T cell proliferation and induces Th1 polarization in peripheral blood mononuclear cells, which is associated with the pathogen...
T73001	EIF4A3-IN-9
	eIF4A3-IN-9, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 29, 450, and 80 nM for myc-LUC, tub-LUC, and growth inhibition in MBA-MB-231 cells, respectively. It i...
T72943	EIF4A3-IN-17
	eIF4A3-IN-17, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 0.9, 15, and 1.8 nM for myc-LUC, tub-LUC, and growth inhibition of MBA-MB-231 cells, respectively. Th...
T71184	ARQ-736
	ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mutations were detected in over 60% of melanomas and may acco...
T73652	Eritoran
	Eritoran, a Toll-like receptor 4 (TLR4) antagonist, effectively protects mice from lethal infections caused by viruses such as the Ebola virus (EBOV) and Marburg virus (MARV). By decreasing granulocytosis levels, Eritora...
T35802	ML-345
	Insulin-degrading enzyme (IDE) is a thiol-sensitive zinc-metallopeptidase that acts as the major insulin-degrading protease in vivo, mediating the termination of insulin signaling. [1] In addition to regulating insulin a...
T37620	Leukotriene C4 methyl ester
	Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular met...
T60271	SARS-CoV-2 nsp3-IN-2
	SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with IC 50 value of 180 μM. SARS-CoV-2 nsp3 macrodomain is an ADP-ribosylhydrolase that is critical for coronavirus replication and pathogenesis. SAR...
T80699	β Amyloid(28-35) human
	β-Amyloid(28-35) human is a neurotoxic β-amyloid peptide fragment that contributes to Alzheimer's disease pathogenesis by interacting with neuronal membranes, modulating its secondary structure and toxicity. It also exhi...
T72944	EIF4A3-IN-18
	eIF4A3-IN-18, a silvestrol analogue, disrupts the formation of the eIF4F translation complex, exhibiting EC 50 values of 0.8, 35, and 2 nM for myc-LUC, tub-LUC, and the growth inhibition of MBA-MB-231 cells, respectively...
TP2177	Amyloid Precursor C-Terminal Peptide		Others
	Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 3...		Others
T82316	GIP, rat TFA
	GIP, rat TFA (glucose-dependent insulinotropic polypeptide), a 42-amino acid peptide secreted by K cells in the duodenum and jejunum, promotes insulin release from pancreatic beta cells, supports beta cell proliferation,...
T37745	N-pentadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma...
T37737	N-cis-octadec-9Z-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm form...
T35498	β-Amyloid (1-14),mouse,rat
	β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-se...
T37878	N-tridecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma...
T37879	N-undecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma...
T37738	N-cis-tetradec-9Z-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm form...
T37336	N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma...
T38128	Leukotriene D4	Leukotriene D4 MaxSpec® Standard,LTD4
	Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. It is the first cysteinyl-leukotriene metabolite of LTC4...
T37743	N-octadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma...
T37582	Ganglioside GM1 Mixture (ovine) (ammonium salt)
	Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched i...

Compounds

Iptacopan hydrochloride

T9189

Synonym: Iptacopan HCl,LNP023 hydrochloride

Target: Complement System

Amyloid β Peptide (42-1)(human) acetate

TP1359L

Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase

β-Amyloid (42-1), human

TP1359

Synonym: Amyloid β Peptide (42-1)(human)

Target:

[Des-His1,Glu9]-Glucagon amide TFA

T36638

Synonym: [Des-His1,Glu9]-Glucagon amide TFA

Synonym: KH-176,KH 176,KH176

Target:

FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)

β-Amyloid (1-42), human

TP1007

Synonym: β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human

Target: Beta Amyloid

Patamostat mesylate

T38521

Synonym: E-3123 mesylate

β Amyloid(17-28) human

T80700

Synonym:

Target:

RORγt Inverse agonist 10

Biotin-β-Amyloid (1-42), human TFA

T80035

Synonym: Biotin-amyloid β-peptide (1-42) (human) TFA

Target:

(3S,4S)-Tivantinib

T83557

Synonym: ARQ 198,(3S,4S)-ARQ 197

Myelin Basic Protein(87-99) TFA

Leukotriene C4 methyl ester

β Amyloid(28-35) human

Amyloid Precursor C-Terminal Peptide

N-pentadecanoyl-L-Homoserine lactone

T37745

Synonym:

Target:

N-cis-octadec-9Z-enoyl-L-Homoserine lactone

T37737

Synonym:

Target:

β-Amyloid (1-14),mouse,rat

T35498

Synonym:

Target:

N-tridecanoyl-L-Homoserine lactone

T37878

Synonym:

Target:

N-undecanoyl-L-Homoserine lactone

T37879

Synonym:

Target:

N-cis-tetradec-9Z-enoyl-L-Homoserine lactone

T37738

Synonym:

Target:

N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone

Synonym: Leukotriene D4 MaxSpec® Standard,LTD4

Target:

N-octadecanoyl-L-Homoserine lactone

T37743

Synonym:

Target:

Ganglioside GM1 Mixture (ovine) (ammonium salt)

T37582

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T41242	Uric acid sodium		Reactive Oxygen Species
	Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) suc...		Reactive Oxygen Species
T39168	Epsilon-(gamma-glutamyl)-lysine	Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH
	Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that forms bonds between extracellular matrix (ECM) components with the assistance of the enzyme tissue transglutaminase (tTg). These bonds are implicat...
TN4822	Prehelminthosporol		Antifection
	Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facilitating nutrient uptake and further growth of the fungus in ...		Antifection

Natural Products

Uric acid sodium

T41242

Synonym:

Target: Reactive Oxygen Species

Epsilon-(gamma-glutamyl)-lysine

T39168

Synonym: Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01457	GLIPR1 Protein, Human, Recombinant (His)	Human	HEK293
	Glioma pathogenesis-related protein 1, also known as Protein RTVP-1, GLIPR1 and GLIPR, is a single-pass membrane protein which belongs to theCRISP family. GLIPR1 / RTVP-1 was expressed in high levels in glioblastomas,...
TMPY-03940	GLIPR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Glioma pathogenesis-related protein 1, also known as Protein RTVP-1, GLIPR1 and GLIPR, is a single-pass membrane protein which belongs to theCRISP family. GLIPR1 / RTVP-1 was expressed in high levels in glioblastomas,...
TMPK-00735	CXCL13/BCA-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li...
TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His)	Human	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His)	Human	HEK293
	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPJ-00575	IL-13 Protein, Human, Recombinant (His)	Human	Human Cells
	Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages...
TMPY-01167	E-Selectin/CD62E Protein, Human, Recombinant (His)	Human	HEK293
	E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involv...
TMPY-04989	Galectin-9 Protein, Human, Recombinant (hFc)	Human	HEK293
	LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix ...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPY-00130	VISTA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by in...
TMPY-02970	CXCL10 Protein, Human, Recombinant	Human	E. coli
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple...
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His)	Human	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ...
TMPY-03219	VISTA Protein, Human, Recombinant (His)	Human	HEK293
	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by in...
TMPY-05453	TSLP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ...
TMPY-02428	TSLP Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ...
TMPY-02881	RAGE Protein, Human, Recombinant	Human	HEK293
	Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02927	RAGE Protein, Human, Recombinant (His)	Human	HEK293
	Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02590	HMGB1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-01848	HMGB1 Protein, Human, Recombinant (aa 1-215, His)	Human	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-04832	OX40L/TNFSF4 Protein, Human, Recombinant (hFc)	Human	HEK293
	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPY-01355	Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TMPY-01601	AXL Protein, Human, Recombinant (His)	Human	HEK293
	Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	Yeast
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-01045	IL-12B Protein, Human, Recombinant (His)	Human	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-03516	IL-12B Protein, Mouse, Recombinant	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-03198	IL-12B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-01298	CADM1 Protein, Human, Recombinant (His)	Human	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular...
TMPY-01870	IL-9 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates...
TMPY-00855	IL-25/IL17E Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 1...
TMPY-00843	IL-25/IL17E Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 1...
TMPY-04356	GSK3B Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPY-01028	Ficolin 1/FCN1 Protein, Human, Recombinant (His)	Human	HEK293
	Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader ...
TMPY-01278	Apolipoprotein H/APOH Protein, Human, Recombinant (His)	Human	HEK293
	Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipop...
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a)	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-01919	MMP-9 Protein, Mouse, Recombinant	Mouse	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-00888	MMP-9 Protein, Human, Recombinant (His)	Human	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-01248	MMP-9 Protein, Human, Recombinant	Human	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-00740	SDF-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-00904	Urokinase/uPA Protein, Human, Recombinant (His)	Human	HEK293
	Plasminogen activator, urokinase, also known as PLAU and uPA, is a serine protease which converts plasminogen to plasmin, a broad-spectrum protease active on extracellular matrix (ECM) components. It is involved in compl...
TMPY-02591	SDF-1 Protein, Human, Recombinant	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His)	Human	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-01209	IL-7R alpha/CD127 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp...
TMPY-00635	IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp...
TMPH-02402	Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)	Legionella pneumophila	E. coli
	Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease.
TMPH-03097	Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc)	Phytophthora cryptogea	E. coli
	Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families. Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins....
TMPH-03715	Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO)	Yersinia enterocolitica	E. coli
	Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. Could play an important role in pathogenesis.
TMPK-00631	DR3/TNFRSF25 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly e...
TMPH-03719	YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)	Yersinia enterocolitica	E. coli
	Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to...
TMPH-03162	Serralysin Protein, Proteus mirabilis, Recombinant (His & SUMO)	Proteus mirabilis	E. coli
	One of the virulence factors produced during swarmer cell differentiation of the bacteria, which seems to be associated with pathogenesis. The protease activity is limited to IgA1, IgA2, as well as IgG degradation.
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GLIPR1 Protein, Human, Recombinant (His)

TMPY-01457

Species: Human

Expression System: HEK293

GLIPR1 Protein, Mouse, Recombinant (His)

TMPY-03940

Species: Mouse

Expression System: HEK293

CXCL13/BCA-1 Protein, Mouse, Recombinant (His)

TMPK-00735

Species: Mouse

Expression System: HEK293

Prolactin Receptor Protein, Human, Recombinant (His)

TMPY-01053

Species: Human

Expression System: HEK293

GITR/TNFRSF18 Protein, Human, Recombinant (His)

TMPY-00072

Species: Human

Expression System: HEK293

IL-13 Protein, Human, Recombinant (His)

TMPJ-00575

Species: Human

Expression System: Human Cells

E-Selectin/CD62E Protein, Human, Recombinant (His)

TMPY-01167

Species: Human

Expression System: HEK293

Galectin-9 Protein, Human, Recombinant (hFc)

TMPY-04989

Species: Human

Expression System: HEK293

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

TMPY-02575

Species: Human

Expression System: Baculovirus-Insect Cells

VISTA Protein, Mouse, Recombinant (hFc)

TMPY-00130

Species: Mouse

Expression System: HEK293

CXCL10 Protein, Human, Recombinant

TMPY-02970

Species: Human

Expression System: E. coli

TSLP Protein, Human, Recombinant (R127A & R130S, His)

TMPY-05220

Species: Human

Expression System: HEK293

VISTA Protein, Human, Recombinant (His)

TMPY-03219

Species: Human

Expression System: HEK293

TSLP Protein, Cynomolgus, Recombinant (His)

TMPY-05453

Species: Cynomolgus

Expression System: HEK293

TSLP Protein, Mouse, Recombinant (His)

TMPY-02428

Species: Mouse

Expression System: HEK293

RAGE Protein, Human, Recombinant

TMPY-02881

Species: Human

Expression System: HEK293

RAGE Protein, Human, Recombinant (His)

TMPY-02927

Species: Human

Expression System: HEK293

HMGB1 Protein, Mouse, Recombinant (hFc)

TMPY-02590

Species: Mouse

Expression System: HEK293

HMGB1 Protein, Human, Recombinant (aa 1-215, His)

TMPY-01848

Species: Human

Expression System: HEK293

OX40L/TNFSF4 Protein, Human, Recombinant (hFc)

TMPY-04832

Species: Human

Expression System: HEK293

Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

TMPY-01355

Species: Human

Expression System: Baculovirus-Insect Cells

AXL Protein, Human, Recombinant (His)

TMPY-01601

Species: Human

Expression System: HEK293

ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)

TMPY-05435

Species: Human

Expression System: HEK293

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: Yeast

IL-12B Protein, Human, Recombinant (His)

TMPY-01045

Species: Human

Expression System: HEK293

IL-12B Protein, Mouse, Recombinant

TMPY-03516

Species: Mouse

Expression System: HEK293

IL-12B Protein, Mouse, Recombinant (His)

TMPY-03198

Species: Mouse

Expression System: HEK293

CADM1 Protein, Human, Recombinant (His)

TMPY-01298

Species: Human

Expression System: HEK293

IL-9 Protein, Human, Recombinant (His)

TMPY-01870

Species: Human

Expression System: Baculovirus-Insect Cells

IL-25/IL17E Protein, Mouse, Recombinant (His)

TMPY-00855

Species: Mouse

Expression System: HEK293

IL-25/IL17E Protein, Human, Recombinant (hFc)

TMPY-00843

Species: Human

Expression System: HEK293

GSK3B Protein, Human, Recombinant (His)

TMPY-04356

Species: Human

Expression System: Baculovirus-Insect Cells

Ficolin 1/FCN1 Protein, Human, Recombinant (His)

TMPY-01028

Species: Human

Expression System: HEK293

Apolipoprotein H/APOH Protein, Human, Recombinant (His)

TMPY-01278

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant (isoform a)

TMPY-02820

Species: Human

Expression System: E. coli

MMP-9 Protein, Mouse, Recombinant

TMPY-01919

Species: Mouse

Expression System: HEK293

MMP-9 Protein, Human, Recombinant (His)

TMPY-00888

Species: Human

Expression System: HEK293

MMP-9 Protein, Human, Recombinant

TMPY-01248

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant (hFc)

TMPY-00740

Species: Human

Expression System: HEK293

Urokinase/uPA Protein, Human, Recombinant (His)

TMPY-00904

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant

TMPY-02591

Species: Human

Expression System: E. coli

ANGPTL2 Protein, Human, Recombinant (His)

TMPY-05053

Species: Human

Expression System: HEK293

IL-7R alpha/CD127 Protein, Human, Recombinant (His)

TMPY-01209

Species: Human

Expression System: HEK293

IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)

TMPY-00635

Species: Cynomolgus

Expression System: HEK293

Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)

TMPH-02402

Species: Legionella pneumophila

Expression System: E. coli

Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc)

TMPH-03097

Species: Phytophthora cryptogea

Expression System: E. coli

Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO)

TMPH-03715

Species: Yersinia enterocolitica

Expression System: E. coli

DR3/TNFRSF25 Protein, Mouse, Recombinant (His)

TMPK-00631

Species: Mouse

Expression System: HEK293

YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)

TMPH-03719

Species: Yersinia enterocolitica

Expression System: E. coli

Serralysin Protein, Proteus mirabilis, Recombinant (His & SUMO)

TMPH-03162

Species: Proteus mirabilis

Expression System: E. coli

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Cat No.	Product Name
L2195	Anti-Prostate Cancer Compound Library	2096 compounds
	2096 compounds associated with prostate cancer that can be used for high-throughput and high-content screening.
L1510	Nuclear Receptor Compound Library	546 compounds
	A unique collection of 546 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L5400	Anti-Cardiovascular Disease Compound Library	1428 compounds
	A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L8600	Ubiquitination Compound Library	214 compounds
	A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening；
L6140	Saccharide and Glycoside Natural Product Library	364 compounds
	A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS；
L2510	Lipid Metabolism Compound Library	496 compounds
	A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
L6740	Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library	386 compounds
	A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.