microtubule-associated protein tau

Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.

4331-0219 is a high-purity biochemical reagent with CAS number 56617-44-8, suitable for biochemical experiments and drug synthesis research.

PTC-700 is an effective splicing modulator of microtubule-associated protein tau (MAPT). It reduces 4R MAPT in P301L and S305N neurons with EC50 values of 1.3 to 1.8 nM and 0.5 to 2.6 nM, respectively.

NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.

TTBK1-IN-1 (compound 31) is a potent and selective tau microtubule protein kinase 1 (TTBK1) inhibitor (IC50=315 nM) with central nervous system (CNS) penetration that inhibits tau phosphorylation at the disease-associated Ser 422 epitope, and can be used to study Alzheimer's disease.

Tilavonemab (ABBV-8E12) is a monoclonal antibody that binds to the N-terminus of the human microtubule-associated protein tau and targets tau protein by binding to amino acid residues at the N-terminal end of tau protein. Tilavonemab blocks the ability of human and mouse neurons to uptake tau aggregates and can be used to study neurological diseases.

Zagotenemab is a humanized antibody against the microtubule-associated protein tau that selectively regulates tau deposits in the brain. Zagotenemab can be used to study neurological disorders such as Alzheimer's disease.

Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].