ldopa

L-DOPA (Levodopa) is an orally active metabolic precursor of the neurotransmitter dopamine. It can cross the blood-brain barrier and be converted into dopamine in the brain. L-DOPA exhibits anti-hyperalgesic effects and holds potential in Parkinson’s disease research, and it can also be used to induce Parkinson’s disease models.

L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.

Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic.

Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.

4-O-Methyldopamine hydrochloride ,with CAS No. 645-33-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-O-Methyldopamine hydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts

Methyldopate HCl is an agent of antihypertensive.

Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).

Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension.

N,N-Dipropyldopamine is a dopamine receptor agonist.1,2,3 It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum of reserpinized rats (ED50s = 25 and 20 μmol/kg, respectively), as well as reduces homovanillic acid levels in rat striatum when administered at a dose of 80 μmol/kg.1 N,N-Dipropyldopamine (0.5-16 mg/kg) reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.2,3

N-Acetyldopamine is a natural catecholamine exhibiting immunomodulatory and antioxidant effects, capable of attenuating LPS-induced TNF-α and superoxide production in THP-1 cells. It inhibits sepiapterin reductase activity.

N-Methyldopamine hydrochloride (Ephinine hydrochloride) is a precursor of adrenaline in the adrenal medulla, an α- and β-agonist with indirect sympathomimetic activity of dopamine.

N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1 agonist with an EC50 value of ~50 nM.

N-(E)-Caffeoyldopamine is capable of interacting with proteins and other molecules in a variety of ways and has been used to study protein-protein interactions as well as enzyme-substrate interactions.

Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

Methyldopa anhydrous is a Central alpha-2 Adrenergic Agonist. The mechanism of action of methyldopa anhydrous is as an Adrenergic alpha2-Agonist.

Fenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist. It acts as a vasodilator in vivo and does not readily cross the blood-brain barrier. Fenoldopam HCl is also an α2-adrenoceptor antagonist in vitro.

Fenoldopam hydrobromide is a Dopamine D1-receptor agonist that acts as an antihypertensive.

N-β-Alanyldopamine hydrochloride (NBAD hydrochloride) represents the primary dopamine derivative found in haemolymph [1].

N-Acetyldopamine dimer-2 (compound 2), an N-acetyldopamine dimer derived from the yellow powder of Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties by inhibiting oxidized low-density lipoprotein (LDL) oxidation, reducing reactive oxygen species (ROS) generation and nitric oxide (NO) production, and suppressing NF-κB activity [1].

N-Acetyldopamine dimer-3 (Compound 11), a naturally occurring chemical, is present in the species Aspongopus chinensis [1].

3-O-Methyldopa-d3 is a deuterated compound of 3-O-Methyldopa. 3-O-Methyldopa has a CAS number of 300-48-1.

Methyldopa-d3 is a deuterated compound of Methyldopa. Methyldopa has a CAS number of 6014-30-8.

N-Acetyldopamine dimer-1, a 2-(3',4'-dihydroxyphenyl)-1,4-benzodioxane derivative, is optically active and can be isolated from the crude agent "Zentai," the cast-off shell of the cicada of Cryptotympana sp. (Cicadidae) [1].