Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • PD-1/PD-L1
    (31)
  • Apoptosis
    (22)
  • Endogenous Metabolite
    (21)
  • TLR
    (21)
  • IL Receptor
    (20)
  • TNF
    (15)
  • STING
    (12)
  • NF-κB
    (11)
  • HIV Protease
    (10)
  • Others
    (343)
Filter
Search Result
Results for "

immune

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    847
    TargetMol | Inhibitors_Agonists
  • Compound Libraries
    18
    TargetMol | Compound_Libraries
  • Peptide Products
    77
    TargetMol | Peptide_Products
  • Inhibitory Antibodies
    106
    TargetMol | Inhibitory_Antibodies
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
  • PROTAC Products
    13
    TargetMol | PROTAC
  • Natural Products
    95
    TargetMol | Natural_Products
  • Reagent Kits
    2
    TargetMol | Reagent_Kits
  • Recombinant Protein
    442
    TargetMol | Recombinant_Protein
  • Isotope Products
    12
    TargetMol | Isotope_Products
  • Antibody Products
    5
    TargetMol | Antibody_Products
  • Disease Modeling
    10
    TargetMol | Disease_Modeling_Products
  • Cell Research
    67
    TargetMol | Inhibitors_Agonists
BAY-218
AHR antagonist 1
T56222162982-11-6
Bindarit (AF2838)is an aryl hydrocarbon receptor (AHR) antagonist with IC50 of 39.9 nM in the human glioblastoma U87 cell line. BAY-218 inhibition of AhR stimulates pro-inflammatory monocyte and T cell responses in vitro and drives anti-tumor immune responses, leading to reduced tumor growth in vivo.
  • $34
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Taurochenodeoxycholic Acid
TCDCA, Taurochenodeoxycholate, Chenyltaurine, Chenodeoxycholyltaurine, 12-Deoxycholyltaurine
T2A2481516-35-8
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
  • $39
In Stock
Size
QTY
Pyrroloquinoline quinone disodium salt
Methoxatin disodium salt
T5693122628-50-6
Pyrroloquinoline quinone disodium salt (Methoxatin disodium salt), an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic substrates to molecular oxygen (O2), constructing quinoprotein model reactions.
  • $50
In Stock
Size
QTY
Taurochenodeoxycholic acid sodium
Sodium taurochenodeoxycholate
TN22156009-98-9
Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties. It can increase glucose-induced insulin secretion and stimulate the electrical activity of α2-cells and enhance cytosolic Ca(2+) concentration ([Ca(2+)](c)).
  • $46
In Stock
Size
QTY
sitravatinib
MGCD516, MG516
T43491123837-84-2
Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα β, PDGFR, and Axl.
  • $47
In Stock
Size
QTY
RVX-297
RVX297
T286281044871-04-6
RVX-297 is a BD2 selective inhibitor of BET bromodomains. RVX-297 preferentially binds to the BD2 domains of the BET bromodomain and Extra Terminal (BET) family of protein.
  • $41
In Stock
Size
QTY
TargetMol | Inhibitor Sale
3-Oxo-5β-cholanoic acid
DHLCA, Dehydrolithocholic acid
T135021553-56-6
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) is a bile acid metabolite that inhibits TH17 cell differentiation by directly binding to the transcription factor RORγt with a Kd of 1.13 μM.
  • $41
In Stock
Size
QTY
N-Hydroxypipecolic acid
NHP, 1-Hydroxy-2-piperidinecarboxylic acid
T19458115819-92-6
N-Hydroxypipecolic acid (NHP) is a plant metabolite and a systemic acquired resistance (SAR) regulator.
  • $53
In Stock
Size
QTY
Pyrroloquinoline quinone
T569272909-34-3
Pyrroloquinoline quinone (PQQ), as a well-known redox enzyme cofactor, PQQ can protect NS/PCs against glutamate toxicity associated with ROS-mediated mitochondrial pathway,
  • $32
In Stock
Size
QTY
AMG-47a
T7123882663-88-9
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
  • $38
In Stock
Size
QTY
GPR34 receptor antagonist 2
Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-, gpr34-receptor-antagonist-2
T8848907952-06-1
GPR34 receptor antagonist 2 (Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) is an anti-inflammatory agent.
  • $118
In Stock
Size
QTY
CID44216842
KUC103479N-02
T89301222513-26-9
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
  • $30
In Stock
Size
QTY
KA2507
T91481636894-46-6
KA2507 is a potent and selective HDAC6 inibitor with an IC50 of 2.5nM.
  • $35
In Stock
Size
QTY
Immune cell migration-IN-2
T820732260679-24-9
Immune cell migration-IN-2 is a potent inhibitor of immune cell migration, exhibiting an EC50 value of 13.5 nM in a T-cell adhesion assay. This compound is utilized in research pertaining to dry-eye and other retinal diseases [1]. As a click chemistry reagent, Immune cell migration-IN-2 possesses an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
  • Inquiry Price
8-10 weeks
Size
QTY
Immune cell migration-IN-1
T820742316683-71-1
Immune cell migration-IN-1 (compound 2) is a potent inhibitor of immune cell migration and has potential research applications for mitigating conditions like dry eye diseases, eczema dermatitis, and psoriasis [1].
  • Inquiry Price
8-10 weeks
Size
QTY
Corticosterone
Kendall's compound B, Corticosterone (From plants), 17-Deoxycortisol, 11β,21-Dihydroxyprogesterone
T0948L50-22-6
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stress responses in the body.
  • $30
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Penicillamine
D-penicillamine, Dimethyl Cysteine, D-(-)-Penicillamine, Artamine
T098352-67-5
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, Artamine chelates with heavy metals and increases their urinary excretion.
  • $42
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Lipopolysaccharides
LPS
T11855
Lipopolysaccharides (LPS), derived from Escherichia coli O55:B5, are essential components of the outer membrane of Gram-negative bacteria. Composed of lipid A, a core oligosaccharide, and an O-specific polysaccharide, LPS exhibits strong immunogenicity. It activates immune cells via the TLR4 receptor, induces chemotactic cell migration and cytokine secretion, and helps maintain the integrity of the bacterial outer membrane, protecting against bile salts and lipid-based antibiotics. LPS is commonly used to establish inflammatory models, including arthritis, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), and gastrointestinal disease models.
  • $45
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Astragaloside IV
AST-IV, AS-IV
T297384687-43-4
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1 2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
  • $32
In Stock
Size
QTY
TargetMol | Inhibitor Hot
BMS-202
PD1-PDL1 inhibitor 2, PD-1 PD-L1 inhibitor 2
T31461675203-84-5
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) PD-Ll (Programmed death-ligand 1) protein protein interaction.
  • $57
In Stock
Size
QTY
TargetMol | Inhibitor Hot
BMS-1
PD1-PDL1 inhibitor 1, PD-1 PD-L1 inhibitor 1
T36551675201-83-8
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
  • $35
In Stock
Size
QTY
TargetMol | Inhibitor Hot
D18
T613902230218-36-5
D18 is an immune modulator that acts as a dual agonist for TLR7 8 (with EC50 values of 24 nM for hTLR7 and 10 nM for hTLR8, respectively). It enhances the expression of PD-L1 through epigenetic regulation, thereby increasing the sensitivity of tumors to PD-1 PD-L1 blockade. Additionally, D18 functions as a cytotoxin for ADC synthesis, specifically for the ADC HE-S2 [1].
  • $1,520
10-14 weeks
Size
QTY
TargetMol | Inhibitor Hot
Dazostinag disodium
T724822553413-93-5In house
Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist that triggers STING signaling pathway activation and type I interferon activation. Dazostinag disodium (TAK-676) is also a highly effective immune system modulator with complete resolution and lasting memory of T cell immunity and the ability to promote lasting interferon-dependent anti-tumor immune responses.
  • $498 TargetMol
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Monalizumab
T766911228763-95-8
Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NKG2A that induces IFN-γ production, thereby activating natural killer cell function. Monalizumab has antitumor activity and can be used to study neck squamous cell carcinoma (HNSCC).
  • $438
In Stock
Size
QTY
TargetMol | Inhibitor Hot