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Search Results for "immune"

Libraries

Immuno-Oncology Compound Library Exosome Compound Library Saccharide and Glycoside Natural Product Library Gut Microbial Metabolite Library Toxic Compound Library Immunology/Inflammation Compound Library Chemotherapy Drug Library Chemokine Inhibitor Library Cytokine Inhibitor Library Bioactive Lipid Compound Library Anti-virus Traditional Chinese Medicine Monomer Library JAK-STAT Compound Library Angiogenesis related Compound Library Anti-Gastroenteritis Natural Product Library Hematonosis Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library NF-κB Signaling Compound Library Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library HIF-1 Signaling Pathway Compound Library Glutamine Metabolism Compound Library
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Compounds

Cat No. Product Name
T10565 BMS-1001 hydrochloride PD-1/PD-L1
BMS-1001 hydrochloride 是一种人 PD-L1/PD-1免疫检查点的抑制剂，具有口服活性且细胞毒性低。
T3382 Wilforlide A 雷公藤内酯甲,Regelide,3-Epiabruslactone A,Abruslactone A Tyrosinase
Wilforlide A 是一种具有生物活性的三萜，从雷公藤中分离得到，具有抗炎和免疫抑制活性。
T5697 BMS-1166 PD-1/PD-L1
BMS-1166 是 PD-1/PD-L1免疫检查点抑制剂。它促使 PD-L1 形成 PD-L1 同源二聚体，进而阻断其与 PD-1 的相互作用，其 IC50为 1.4 nM。它阻断了 PD-1/PD-L1 免疫检查点对 T 细胞活化的抑制...
TN1686 Ginsenoside Rg4 人参皂苷 RG4 Antibacterial
Ginsenoside Rg4 是分离自Panax ginsengC. A. Meyer 叶子中的一种人参三醇型人参皂苷。人参三醇型人参皂苷具有多种生物活性，包括防腐，抗糖尿病，伤口愈合，免疫刺激和抗氧化活性等。
TN2215 Taurochenodeoxycholic acid sodium 牛磺鹅去氧胆酸钠盐,牛磺鹅去氧胆酸钠,Sodium taurochenodeoxycholate Endogenous Metabolite , Apoptosis
Taurochenodeoxycholic acid sodium 是动物胆汁酸的主要生物活性物质之一。它可诱导细胞凋亡，具有抗炎和免疫调节作用。
T9148 KA2507 HDAC
KA2507 是一种具有口服活性的选择性HDAC6抑制剂， 其IC50值为 2.5 nM。它有抗肿瘤活性和免疫调节作用。
T4940 3-Methylhistamine dihydrochloride Endogenous Metabolite , Others
3-Methylhistamine dihydrochloride 是一种组胺的降解产物，与免疫反应有关，并在接种过疫苗的小鼠中表现出上调作用。
T6828 ZL0420 Epigenetic Reader Domain
ZL0420 是有效且选择性的 BET 溴结构域 4 (BRD4) 抑制剂，对 BRD4 的溴结构域 (BD) 具有纳摩尔结合亲和力。ZL0420 对 BRD4 BD1和 BRD4 BD2 的IC50分别为 27 nM 和 32 nM。
T5692 Pyrroloquinoline quinone Others , Endogenous Metabolite
Pyrroloquinoline quinone 是氧化还原辅助因子，一种阴离子型氧化还原循环原醌。它是哺乳动物的必需营养素，对免疫功能很重要。它最初是从嗜甲基细菌的培养物中分离的，也存在于哺乳动物的组织。
T28628 RVX-297 RVX297 Epigenetic Reader Domain
RVX-297 是口服具有活性的，对BD2有选择性的BET 高效抑制剂，作用于BRD2(BD2)、BRD3(BD2)、BRD4(BD2) 的IC50分别为 0.08、0.05、0.02 μM。它能够阻碍多种免疫细胞炎症基因的表达，对临床前模...
T38361 GSK717 IL Receptor , NOD
GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导，抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T12933 SM-276001 TLR , COX
SM-276001 是可口服的干扰素诱导剂，是选择性TLR7激动剂，可以诱导抗肿瘤免疫反应。
T8930 CID44216842 KUC103479N-02 CDK , Ras
CID44216842 是Cdc42选择性抑制剂。在 GDP 结合测定中，它对 Cdc42 野生型和 Cdc42Q61L 突变型的EC50分别为 0.3 和 0.5 μM。在 GTP 结合测定中，它对 Cdc42 野生型和 Cdc42Q61...
T19458 N-Hydroxypipecolic acid NHP,1-Hydroxy-2-piperidinecarboxylic acid Others
N-Hydroxypipecolic acid 是植物代谢产物和系统性获得性抗性调节剂，可与免疫信号水杨酸协调建立系统性获得性抗性，诱导系统获得性耐药对细菌和卵菌感染。它在植物叶片中系统地积累，以应对病原菌的侵袭。
T3146 BMS-202 PD-1/PD-L1 inhibitor 2,PD1-PDL1 inhibitor 2 Apoptosis , PD-1/PD-L1
BMS-202 是一种非肽类 PD-1/PD-L 复合物抑制剂，其 IC50为 18 nM，KD 为 8 μM。它与 PD-L1 直接结合并阻断人类 PD-1/PD-L 的相互作用，具有抗肿瘤活性。
T4328 OSS_128167 SIRT6-IN-1 Sirtuin , HBV
OSS_128167 是一种选择性沉默调节蛋白 6 (SIRT6) 抑制剂，对 SIRT6，SIRT1 和 SIRT2 的 IC50分别为 89 μM，1578 μM 和 751 μM。它具有抗 HBV、抗癌、抗炎和抗病毒活性，可抑制 HB...
T8689 Chloroquine TLR , Autophagy , Parasite , HIV Protease , Antibiotic , SARS-CoV
Chloroquine 是一种自噬和 Toll 样受体抑制剂。 氯喹是一种抗疟疾和抗炎剂，广泛用于治疗疟疾和类风湿性关节炎。它在体外控制 SARS-CoV-2 (COVID-19) 感染方面非常有效，EC50 为 1.13 μM。
T5125 LY3200882 TGF-beta/Smad
LY3200882 是一种高度选择性的、口服活性的、具有 ATP 竞争性的 TGF-β 受体 1 型 (ALK5) 抑制剂(IC50:38.2 nM)。它能够抑制多种促肿瘤活性，可用作免疫调节剂。
T0983 Penicillamine D-青霉胺,青霉胺,D-(-)-Penicillamine,d-penicillamin,Artamine,Dimethyl Cysteine Antibiotic
d-penicillamin 是一种 penicillin 的代谢降解产物，是一种螯合剂，可作用于威尔逊氏病。
T7123 AMG-47a JAK , VEGFR , p38 MAPK , Src
AMG-47a 是具有口服活性的 Lck 抑制剂，IC50值为 0.2 nM。它具有抗炎作用，对 VEGF2、p38α、p38α、Jak3、MLR 和 IL-2的 IC50值分别为 1、3、72、30 和 21 nM。
BMS-1001 hydrochloride
T10565
synonym:
Target:
Wilforlide A
T3382
synonym: 雷公藤内酯甲,Regelide,3-Epiabruslactone A,Abruslactone A
Target:
BMS-1166
T5697
synonym:
Target:
Ginsenoside Rg4
TN1686
synonym: 人参皂苷 RG4
Target:
Taurochenodeoxycholic acid sodium
TN2215
synonym: 牛磺鹅去氧胆酸钠盐,牛磺鹅去氧胆酸钠,Sodium taurochenodeoxycholate
Target:
KA2507
T9148
synonym:
Target:
3-Methylhistamine dihydrochloride
T4940
synonym:
Target:
ZL0420
T6828
synonym:
Target:
Pyrroloquinoline quinone
T5692
synonym:
Target:
RVX-297
T28628
synonym: RVX297
Target:
GSK717
T38361
synonym:
Target:
SM-276001
T12933
synonym:
Target:
CID44216842
T8930
synonym: KUC103479N-02
Target:
N-Hydroxypipecolic acid
T19458
synonym: NHP,1-Hydroxy-2-piperidinecarboxylic acid
Target:
BMS-202
T3146
synonym: PD-1/PD-L1 inhibitor 2,PD1-PDL1 inhibitor 2
Target:
OSS_128167
T4328
synonym: SIRT6-IN-1
Target:
Chloroquine
T8689
synonym:
Target:
LY3200882
T5125
synonym:
Target:
Penicillamine
T0983
synonym: D-青霉胺,青霉胺,D-(-)-Penicillamine,d-penicillamin,Artamine,Dimethyl Cysteine
Target:
AMG-47a
T7123
synonym:
Target:
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