h 7

Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) inhibited PMA-induced promiscuity cell lysis activity.

Bombinin H7, an antimicrobial peptide originating from the skin secretions of Bombina, exhibits bactericidal activity against Bacillus megaterium Bm11 at a lethal concentration of 25.2 μM [1].

Maximin H7, an antimicrobial peptide, originates from the toad Bombina maxima [1].

Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.

Protein kinase inhibitor H-7 (5-(2-methylpiperazine-1-sulfonyl)isoquinoline) is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.

21H7 is a selective inhibitor of the Wnt/b-catenin pathway. It significantly suppresses the growth of HF and effectively inhibits the proliferation of breast and colon cancer cells.

8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione is a useful organic compound for research related to life sciences. The catalog number is T65626 and the CAS number is 93703-24-3.

8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is a useful organic compound for research related to life sciences. The catalog number is T66320 and the CAS number is 853029-57-9.

PROTAC(H-PGDS)-7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. It effectively inhibits prostaglandin D2 (PGD2) and is a candidate compound for the treatment of DMD and other H-PGDS-related diseases.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilized for research in the fields of chemistry and life sciences.

2,4,5-Trichloro-7H-pyrrolo[2,3-d]pyrimid is a chemical agent.

7-Amino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester ,with CAS No. 171049-41-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Amino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Methyl-3,4-dihydrothieno[3,2-d]pyrimidin-4-one ,with CAS No. 175137-13-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Methyl-3,4-dihydrothieno[3,2-d]pyrimidin-4-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Methoxy-3,4,5,6-tetrahydro-2H-azepine ,with CAS No. 2525-16-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Methoxy-3,4,5,6-tetrahydro-2H-azepine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7H-pyrrolo[2,3-d]pyrimidine ,with CAS No. 271-70-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7H-pyrrolo[2,3-d]pyrimidine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Methylsulfanyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol ,with CAS No. 67831-83-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Methylsulfanyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one ,with CAS No. 22245-92-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

tert-butyl 4-Chloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H) ,with CAS No. 1053657-15-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. tert-butyl 4-Chloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Methyl-1H-indole-7-carboxylic acid ,with CAS No. 167479-16-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Methyl-1H-indole-7-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(4-Methyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl)methylamine ,with CAS No. 946409-08-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (4-Methyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl)methylamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3,4-Dihydro-2H-1,5-benzodioxepin-7-ylmethylamine ,with CAS No. 23475-00-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3,4-Dihydro-2H-1,5-benzodioxepin-7-ylmethylamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1H-1,3-diazepine, 4,5,6,7-tetrahydro-4,4,7,7-tetramethyl-2-(methylthio)-, hydriodide (1:1) ,with CAS No. 99347-30-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H-1,3-diazepine, 4,5,6,7-tetrahydro-4,4,7,7-tetramethyl-2-(methylthio)-, hydriodide (1:1) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4,5-Dihydro-4,7,8-trimethyl-1H-1,5-benzodiazepin-2(3H)-one ,with CAS No. 65847-12-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4,5-Dihydro-4,7,8-trimethyl-1H-1,5-benzodiazepin-2(3H)-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.