Search Result

Search Results for " cytotoxic "

Targets

Others

514

Compounds

357

Natural Products

199

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T40588	Acifluorfen		Others
	Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX) and induces tumors in rodent livers. It causes significant photooxidative damage to pigments a...		Others
T38272	Thiacloprid		AChR , Parasite
	Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 nM forDrosophilanAChRs and M10 mouse fibroblast cells expres...		AChR , Parasite
T12189	NBDHEX		Apoptosis , Glutathione Peroxidase , Autophagy
	NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .		Apoptosis , Glutathione Peroxidase , Autophagy
T21859	ARM1		Aminopeptidase , Epoxide Hydrolase
	ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 µM for aminopeptidase and 12.4 µM for epoxide hydrolase.		Aminopeptidase , Epoxide Hydrolase
T6683	STF-62247	STF 62247	Estrogen/progestogen Receptor , Autophagy
	STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.		Estrogen/progestogen Receptor , Autophagy
T13780	MS1943		Apoptosis , Histone Methyltransferase
	MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).		Apoptosis , Histone Methyltransferase
T9014	SKI-178		Apoptosis , S1P Receptor
	SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...		Apoptosis , S1P Receptor
T15588	Iobenguane sulfate	MIBG sulfate	Others
	Iobenguane sulfate (MIBG sulfate) is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation). Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmac...		Others
T12134	MYCMI-6	NSC354961	Apoptosis , c-Myc
	MYCMI-6 (NSC-354961) is a potent and selective inhibitor of endogenous MYC:MAX protein interactions，reduces proliferation and induces massive apoptosis in tumor tissue from a MYC-driven xenograft tumor model without seve...		Apoptosis , c-Myc
T38562	AKN-028		FLT
	AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.		FLT
T21854	Proteasome inhibitor IX	PS-IX,AM114	Proteasome
	Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). Proteasome inhibitor IX shows potent anticancer activity. Proteasome inhibitor IX exhibits HCT116 p53+/+ c...		Proteasome
T7739	L-Leucyl-L-Leucine methyl ester hydrochloride	Leu-Leu-ome hydrochloride	Others , Endogenous Metabolite
	L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.		Others , Endogenous Metabolite
T0223	Tetrahydroxyquinone	4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone	Apoptosis , Antioxidant , Reactive Oxygen Species
	Tetrahydroxyquinone (Tetroquinone) is a molecule best known as a primitive anticataract drug, is also a highly redox active molecule that can take part in a redox cycle with semiquinone radicals, leading to the formation...		Apoptosis , Antioxidant , Reactive Oxygen Species
T3184	Kevetrin hydrochloride	Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride	Mdm2 , p53
	Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.		Mdm2 , p53
T19712	Levoglucosenone		Others
	Levoglucosenone has cytotoxic. It against human hepatocarcinoma cell lines.		Others
T4434	Tirapazamine	Tirazone,Win59075,SR4233,SR259075	Others
	Tirapazamine (Win59075) is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to oth...		Others
TP1758L	LCMV gp33-41 acetate	LCMV gp33-41 acetate（151705-84-9 Free base）	Others
	LCMV gp33-41 acetate is a sequence of lymphocytic choriomeningitis virus which restricted by major histocompatibility complex class I H-2Db and presented to cytotoxic T lymphocytes.		Others
T14858	Calicheamicin	Calicheamicin γ1	Others
	Calicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.		Others
T68061	Elinafide
	Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.
T0651	N-Phenylbenzylamine	Benzylaniline,Benzenemethanamine	Microtubule Associated
	A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization		Microtubule Associated
T36896	6α-hydroxy Paclitaxel	6alpha-hydroxypaclitaxel	Drug Metabolite
	6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.		Drug Metabolite
T19841	Tribenoside	Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF	Others
	Tribenoside (BG-356) is a vasoprotectant with mild anti-inflammatory, analgesic, and wound healing properties.		Others
T16699	PYZD-4409		Others , E1/E2/E3 Enzyme
	PYZD-4409 is a selective UBA1 inhibitor with an IC50 of 20 μM. PYZD-4409 induces cell death in malignant cells and is preferentially cytotoxic to malignant cells over normal hematopoietic cells.		Others , E1/E2/E3 Enzyme
T27612	INI-43	INI 43,INI43	Others
	INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpn...		Others
T12360	Para-Nitroblebbistatin	p-Nitroblebbistatin	Myosin
	para-Nitroblebbistatin (p-Nitroblebbistatin) is a non-cytotoxic, fluorescent, photostable and specific Myosin II inhibitor. para-Nitroblebbistatin can be used in the study of the special role of myosin II in developmenta...		Myosin
T62525	TP-16		Prostaglandin Receptor
	TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.		Prostaglandin Receptor
T1478	Ondansetron hydrochloride dihydrate	SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride	5-HT Receptor
	Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, a...		5-HT Receptor
T60812	Cathepsin X-IN-1		Cysteine Protease
	Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].		Cysteine Protease
T77466	Tremelimumab	Ticilimumab,CP-675206	Others
	Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and l...		Others
T5872	Faltan	Folpet	Antifungal
	Faltan (Folpet),a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.		Antifungal
T68122	Oxmetidine	SKF 92994,Oxmetidina,Oxmetidinum	Histamine Receptor
	Oxmetidine (SKF 92994) is a novel H2 receptor antagonist that is cytotoxic. Oxmetidine inhibits transmembrane calcium flux in cardiac and vascular tissues and is used in the treatment of active duodenal ulcers.		Histamine Receptor
T17946	Fmoc-Ala-Ala-Asn(Trt)-OH		Others
	Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable linker vital in ADC synthesis. Fmoc-Ala-Ala-Asn(Trt)-OH joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled...		Others
T11728	JR-AB2-011		mTOR
	JR-AB2-011 is a selective mTORC2 inhibitor with an IC 50 value of 0.36 μM. JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association ( K i : 0.19 μM) and is cytotoxic in glioblastoma [1].		mTOR
T77567	BCPA		Others
	BCPA is a non-cytotoxic Pin1 modulator.BCPA modulates osteoclast activation and attenuates the reduction of Pin1 protein, thereby inhibiting RANKL-induced receptor activators of osteoclastogenesis.BCPA is used in the stu...		Others
T18870	Vc-MMAD		Others
	Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs t...		Others
T19051	Reactive Blue 4		Others
	Reactive Blue 4 is an anthraquinone dye with phytotoxic, cytotoxic, and genotoxic. It is a single colorimetric chemosensor for the sequential determination of multiple analytes with different optical responses in aqueous...		Others
T38271	TH1217	TH 1217	Others
	TH1217, a potent and selective inhibitor of dCTPase pyrophosphatase 1 (dCTPase), demonstrates an IC50 value of 47 nM. It amplifies the cytotoxic impact of cytidine analogues on leukemia cells and exhibits potential again...		Others
T14348	Auristatin E		Microtubule Associated
	Auristatin E, a cytotoxic tubulin modifier, disrupts cell division by inhibiting tubulin polymerisation. This compound demonstrates potent and selective antitumor activities, serving as an MMAE analog and cytotoxin in an...		Microtubule Associated
T13298	Verubulin hydrochloride	MPC-6827 hydrochloride	Microtubule Associated
	Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic activities,with potent anticancer activity in human MX-1 brea...		Microtubule Associated
T6798	Tretazicar	5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829	DNA Alkylator/Crosslinker , DNA Alkylation
	CB1954(Tretazicar (NSC-115829)), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cy...		DNA Alkylator/Crosslinker , DNA Alkylation
T68896	Daniquidone	NSC 320846,BAY-H 2049	Topoisomerase
	Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity that induces DNA fragmentation for the study of neoplasms, immune disorder...		Topoisomerase
T20067	WST-1	WST 1
	WST-1 is a cytotoxic, water-soluble tetrazolium salt that induces intracellular mitochondrial dehydrogenases to undergo NADH-dependent enzymatic reactions, releasing water-soluble methylbenzene products.WST-1 can be used...
T16277	NCT-502	N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide	Dehydrogenase
	NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-d...		Dehydrogenase
T8591	RNase L-IN-2	5-(3-hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one	Others
	RNase L-IN-2 is an activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic a...		Others
T36879L	H-Leu-Leu-OMe . HBr	H-Leu-Leu-OMe . HBr (16689-14-8 Free base)	Others
	H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eli...		Others
T83627	Pim-1 kinase inhibitor 8		Pim , PKC
	Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound ...		Pim , PKC
T21314	Amsilarotene	TAC-101,TAC 101,TAC101	CDK
	Amsilarotene (TAC101) inhibits the phosphorylation of retinoblastoma gene product (RB) and increases the presence of 2 cyclin-dependent kinases (CDK) inhibitors resulting in cell cycle arrest. This agent also causes a cy...		CDK
T21704	5-fluoro 203	5F-203,NSC-703786	Others
	5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. 5-fluoro 203 treatment of cells...		Others
T6075	Epothilone B	Patupilone,EPO 906	Apoptosis , Microtubule Associated , Antibiotic , Antifungal
	Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditi...
TP1527	CEF8, Influenza Virus NP (383-391)	CEF8, Influenza Virus NP 383-391	Others
	CEF8, Influenza Virus NP (383-391) is an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated w...		Others

Compounds

Target: AChR, Parasite

NBDHEX

T12189

Synonym:

Target: Apoptosis, Glutathione Peroxidase, Autophagy

ARM1

T21859

Synonym:

Target: Aminopeptidase, Epoxide Hydrolase

STF-62247

T6683

Synonym: STF 62247

Target: Estrogen/progestogen Receptor, Autophagy

MS1943

T13780

Synonym:

Target: Apoptosis, Histone Methyltransferase

SKI-178

T9014

Synonym:

Target: Apoptosis, S1P Receptor

Iobenguane sulfate

T15588

Synonym: MIBG sulfate

Target: Apoptosis, c-Myc

Proteasome inhibitor IX

T21854

Synonym: PS-IX,AM114

Target: Proteasome

L-Leucyl-L-Leucine methyl ester hydrochloride

T7739

Synonym: Leu-Leu-ome hydrochloride

Target: Others, Endogenous Metabolite

Tetrahydroxyquinone

T0223

Synonym: 4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Kevetrin hydrochloride

T3184

Synonym: Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride

Synonym: Tirazone,Win59075,SR4233,SR259075

Target: Others

LCMV gp33-41 acetate

TP1758L

Synonym: LCMV gp33-41 acetate（151705-84-9 Free base）

Target: Others

Calicheamicin

T14858

Synonym: Calicheamicin γ1

Synonym: Benzylaniline,Benzenemethanamine

Target: Microtubule Associated

6α-hydroxy Paclitaxel

T36896

Synonym: 6alpha-hydroxypaclitaxel

Target: Drug Metabolite

Tribenoside

T19841

Synonym: Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF

Target: Others, E1/E2/E3 Enzyme

INI-43

T27612

Synonym: INI 43,INI43

Target: Others

para-Nitroblebbistatin

T12360

Synonym: p-Nitroblebbistatin

Target: Prostaglandin Receptor

Ondansetron hydrochloride dihydrate

T1478

Synonym: SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride

Target: 5-HT Receptor

Cathepsin X-IN-1

T60812

Synonym:

Target: Cysteine Protease

Tremelimumab

T77466

Synonym: Ticilimumab,CP-675206

Synonym: SKF 92994,Oxmetidina,Oxmetidinum

Target: Histamine Receptor

Fmoc-Ala-Ala-Asn(Trt)-OH

Target: Microtubule Associated

Verubulin hydrochloride

T13298

Synonym: MPC-6827 hydrochloride

Target: Microtubule Associated

Tretazicar

T6798

Synonym: 5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829

Target: DNA Alkylator/Crosslinker, DNA Alkylation

Daniquidone

T68896

Synonym: NSC 320846,BAY-H 2049

Target: Topoisomerase

Synonym: N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide

Target: Dehydrogenase

RNase L-IN-2

T8591

Synonym: 5-(3-hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one

Target: Others

H-Leu-Leu-OMe . HBr

T36879L

Synonym: H-Leu-Leu-OMe . HBr (16689-14-8 Free base)

Target: Others

Pim-1 kinase inhibitor 8

Synonym: TAC-101,TAC 101,TAC101

Target: CDK

5-fluoro 203

T21704

Synonym: 5F-203,NSC-703786

Target: Others

Epothilone B

T6075

Synonym: Patupilone,EPO 906

Target: Apoptosis, Microtubule Associated, Antibiotic, Antifungal

CEF8, Influenza Virus NP (383-391)

TP1527

Synonym: CEF8, Influenza Virus NP 383-391

Target: Others

Cat No.	Product Name	Synonyms	Targets
TN7043	Neolancerin		Others
	Neolancerin is a natural product isolated from adventitious roots of St. John’s wort (Hypericum perforatum L.).		Others
T32291	Jineol	NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081	Others
	Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.		Others
TN1722	Hamamelitannin		Antifection
	Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a hig...		Antifection
TN2182	Sarracenin		Others
	Sarracenin is a natural product. Sarracenin shows cytotoxic activities against tumor cells.		Others
TN6512	Tectol		Transferase , Parasite
	Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti...		Transferase , Parasite
T21165	Pellitorine	AI3-19560,Pellitorin	TRP/TRPV Channel
	Pellitorine (Pellitorin) is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist.		TRP/TRPV Channel
TN6720	Acetylalkannin	Acetyl alkannin,Alkannin acetate	Antibacterial
	Acetylalkannin (Alkannin acetate), an isohexenylnaphthazarin pigment extracted from Arnebia euchroma, exhibits antimicrobial and cytotoxic properties.		Antibacterial
T5808	(-)-Oxypeucedanin hydrate	OXYPEUCEDANIN HYDRATE	Others
	(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.		Others
T13741	Isoviolanthin		Others
	Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastat...		Others
T3933	Jatrorrhizine	Yatrorizine,neprotin	MAO , 5-HT Receptor , Antibacterial , AChE
	Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo...		MAO , 5-HT Receptor , Antibacterial , AChE
T4912	Jatrorrhizine chloride	Yatrorhizine chloride,Neprotine chloride	Others , 5-HT Receptor , OCT , Antibacterial , AChE
	Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...		Others , 5-HT Receptor , OCT , Antibacterial , AChE
TN1915	Matairesinol 4′-O-β-D-glucopyranoside	Matairesinol 4'-O-beta-gentiobioside	Others
	Matairesinol 4′-O-β-D-glucopyranoside is a natural product isolated from Trachelospermum jasminoides.		Others
T25664	Lepidiline A	Macaline A	Others
	Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a...		Others
TN2546	1-Isomangostin		NF-κB
	1-Isomangostin has cytotoxic and anticomplementary activities.		NF-κB
T22857	Illudin S		Apoptosis , DNA Alkylator/Crosslinker , Antifungal
	Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.		Apoptosis , DNA Alkylator/Crosslinker , Antifungal
T2S2018	7beta-Hydroxylathyrol	7β-Hydroxylathyrol,7-Hydroxylathyrol,7-beta-Hydroxylathyrol	P-gp
	7β-Hydroxylathyrol is a diterpenoid extract from the seed oil of Caper Spurge and displays P-gp inhibition resulting in cytotoxic properties.		P-gp
T13815	Penicillic acid		Apoptosis , Caspase , Antibacterial , Antibiotic
	Penicillic acid, a polyketide mycotoxin, synthesized by various species of Aspergillus and Penicillium, acts as an inhibitor of Fas ligand-induced apoptosis by impeding self-processing of caspase-8. Additionally, in vitr...		Apoptosis , Caspase , Antibacterial , Antibiotic
T41288	Myristoleic acid	cis-9-tetradecenoic acid,9-Tetradecenoic acid,(Z)-Tetradec-9-enoic acid	Apoptosis
	Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.		Apoptosis
T31866	FR901464	FR 901464,FR-901464,WB 2663B	Others
	FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring.		Others
TN5922	3,4-Dimethoxycinnamyl alcohol	(E)-3-(3,4-dimethoxyphenyl)prop-2-en-1-ol	Others
	3,4-Dimethoxycinnamyl alcohol ((E)-3-(3,4-dimethoxyphenyl)prop-2-en-1-ol) shows significant antimicrobial and cytotoxic activities.		Others
T4S1999	Valepotriate	Valtrate	Apoptosis , HIV Protease
	Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agen...		Apoptosis , HIV Protease
T2S0029	4'-Demethylpodophyllotoxin		Others
	4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.		Others
TN1656	Ganoderenic acid A		Others
	Ganoderenic acid A has a potent hepatoprotective, and cytotoxic effects, it shows inhibitory activity on human aldose reductase in vitro.		Others
TN2430	Glucodigifucoside
	Glucodigifucoside, a cardiac glycoside that can be isolated from digitalis seeds, is specifically cytotoxic to human renal adenocarcinoma cells.
T8206	Cycleanine		Others
	Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.		Others
TN3231	Pratol	7-Hydroxy-4'-methoxyflavone	Others
	Pratol (7-Hydroxy-4'-methoxyflavone) significantly increased melanin content and tyrosinase activity in the cells without being cytotoxic.		Others
T3386	Kaempferitrin	Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside	cell cycle arrest , Glucokinase , IGF-1R
	Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos...		cell cycle arrest , Glucokinase , IGF-1R
TN4375	Kamebanin		Antifection
	Kamebanin, a natural diterpenoid, has antibacterial activity. It also shows efficient cytotoxic activity against HeLa and HL-60 cells.		Antifection
T5S0229	Isosakuranetin	4'-Methylnaringenin	Others
	1. Isosakuranetin (4'-Methylnaringenin) has cytotoxic and fungicide properties. 2. Isosakuranetin produces significant decrease in blood pressure. 3. Isosakuranetin significantly reduces the sensitivity of mice to noxiou...		Others
T5S0168	Atractylenolide II	2-Atractylenolide,Asterolide	Apoptosis , ERK , p38 MAPK , Akt , STAT
	1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK and Akt inactivation, p53 dependent.		Apoptosis , ERK , p38 MAPK , Akt , STAT
TN1018	Angeloylgomisin H		PPAR
	Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.		PPAR
T4S1024	Picfeltarraenin IB		Others , AChE
	1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.		Others , AChE
TN3029	4-(Ethoxymethyl)phenol	p-Hydroxybenzyl Et ether	Antioxidant
	4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a small molecule compound extracted from Amburana cearensis with cytotoxic and antioxidant activity.		Antioxidant
T0501	Mequinol	4-Hydroxyanisole,Leucobasal,4-Methoxyphenol	Others
	Mequinol (Leucobasal) is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosina...		Others
T20091	Stearamide	Stearic acid amide,NSC 66462,NSC66462,NSC-66462
	Stearamide(Stearic acid amide) is a primary fatty acid amide that is cytotoxic and fish toxic and can be used to increase the properties of nanoparticles.
T5744	7-Prenyloxycoumarin	Nsc267697,7-O-Prenylumbelliferone	Antifungal
	7-Prenyloxycoumarin (Nsc267697) is a natural product from Heracleum dissectum,and possess preventive and therapeutic effects on breast cancer but they have also cytotoxic effects on some other cancer cell lines.		Antifungal
TMA2394	DL-alpha-Tocopherol	DL-α-Tocopherol,Alpha-Tochopherol,Ephanyl	Antioxidant , Ferroptosis
	DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.		Antioxidant , Ferroptosis
T2S1593	Gypenoside XLVI		Others
	Gypenoside XLVI shows strong cytotoxic activity against A549 cells, with the IC50 values of 52.63±8.31 ug/ml.		Others
T3S1692	Octahydrocurcumin		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
T10164	5,6-Dihydroxyindole	Dopamine lutine	Endogenous Metabolite
	5,6-Dihydroxyindole (Dopamine lutine) is a melanin precursor and has a broad-spectrum antibacterial, antiviral, antifungal, antiparasitic activity. It has cytotoxic effects and is strongly toxic against various pathogens...		Endogenous Metabolite
T3819	Ursolic acid acetate	Acetylursolic acid,3-Acetylursolic Acid	AChE
	Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition ...		AChE
T5S0777	Phellodendrine chloride		Others
	Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others
T3020	Sclareol		Apoptosis , Others
	Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines.		Apoptosis , Others
TN1174	Schinifoline		Apoptosis , cell cycle arrest
	Schinifoline is a quinolone derivative extracted from Zanthoxylum schinifolium Sieb with cytotoxic activity that promotes radiosensitization of cancer cells, affects the cell cycle and apoptosis.		Apoptosis , cell cycle arrest
T67922	Lepidiline C		Others
	Lepidiline C is a novel imidazoles alkaloids extracted from the root of Lepidium meenii Walpers of the brassaceae family. It has shown cytotoxic activity against HL-60 cells (IC50:27.7 μM).		Others
T3S1534	Secoxyloganin		Anti-infection
	Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on ...		Anti-infection
T6S1485	Ginsenoside Rh4		Others
	1. Ginsenoside Rh4 could be safely used as adjuvant with low or non-haemolytic effect. 2. Ginsenoside Rh4 has cytotoxic activity and its aglycone against cancer cell lines.		Others
T4601	9-Methoxycanthin-6-one		Others
	9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1-4 μg/mL.		Others
TN1087	Deoxypodophyllotoxin		Apoptosis , Microtubule Associated , Autophagy
	Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities.		Apoptosis , Microtubule Associated , Autophagy
T6S0781	Phellodendrine	Phallodendrin	Others , NF-κB , Akt
	1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others , NF-κB , Akt
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Natural Products

Synonym: NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081

Target: Transferase, Parasite

Pellitorine

T21165

Synonym: AI3-19560,Pellitorin

Target: TRP/TRPV Channel

Acetylalkannin

TN6720

Synonym: Acetyl alkannin,Alkannin acetate

Target: Antibacterial

(-)-Oxypeucedanin hydrate

T5808

Synonym: OXYPEUCEDANIN HYDRATE

Synonym: Yatrorizine,neprotin

Target: MAO, 5-HT Receptor, Antibacterial, AChE

Jatrorrhizine chloride

T4912

Synonym: Yatrorhizine chloride,Neprotine chloride

Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE

Matairesinol 4′-O-β-D-glucopyranoside

TN1915

Synonym: Matairesinol 4'-O-beta-gentiobioside

Target: Apoptosis, DNA Alkylator/Crosslinker, Antifungal

7beta-Hydroxylathyrol

T2S2018

Synonym: 7β-Hydroxylathyrol,7-Hydroxylathyrol,7-beta-Hydroxylathyrol

Target: Apoptosis, Caspase, Antibacterial, Antibiotic

Myristoleic acid

T41288

Synonym: cis-9-tetradecenoic acid,9-Tetradecenoic acid,(Z)-Tetradec-9-enoic acid

Target: Apoptosis

FR901464

T31866

Synonym: FR 901464,FR-901464,WB 2663B

Target: Others

3,4-Dimethoxycinnamyl alcohol

TN5922

Synonym: (E)-3-(3,4-dimethoxyphenyl)prop-2-en-1-ol

Target: Apoptosis, HIV Protease

4'-Demethylpodophyllotoxin

Synonym: 7-Hydroxy-4'-methoxyflavone

Target: Others

Kaempferitrin

T3386

Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside

Target: cell cycle arrest, Glucokinase, IGF-1R

Synonym: 4'-Methylnaringenin

Target: Others

Atractylenolide II

T5S0168

Synonym: 2-Atractylenolide,Asterolide

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

4-(Ethoxymethyl)phenol

TN3029

Synonym: p-Hydroxybenzyl Et ether

Target: Antioxidant

Mequinol

T0501

Synonym: 4-Hydroxyanisole,Leucobasal,4-Methoxyphenol

Target: Others

Stearamide

T20091

Synonym: Stearic acid amide,NSC 66462,NSC66462,NSC-66462

Target:

7-Prenyloxycoumarin

T5744

Synonym: Nsc267697,7-O-Prenylumbelliferone

Target: Antifungal

DL-alpha-Tocopherol

TMA2394

Synonym: DL-α-Tocopherol,Alpha-Tochopherol,Ephanyl

Target: Antioxidant, Ferroptosis

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

5,6-Dihydroxyindole

T10164

Synonym: Dopamine lutine

Target: Endogenous Metabolite

Ursolic acid acetate

T3819

Synonym: Acetylursolic acid,3-Acetylursolic Acid

Target: AChE

Phellodendrine chloride

Target: Apoptosis, Others

Schinifoline

TN1174

Synonym:

Target: Apoptosis, cell cycle arrest

Target: Anti-infection

9-Methoxycanthin-6-one

Target: Apoptosis, Microtubule Associated, Autophagy

Phellodendrine

T6S0781

Synonym: Phallodendrin

Target: Others, NF-κB, Akt

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01604	CTLA-4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-05159	Granzyme A/GZMA Protein, Human, Recombinant (His)	Human	HEK293
	Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 cells.
TMPY-04824	CTLA-4 Protein, Human, Recombinant	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His)	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPJ-01172	IL-17 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque...
TMPY-02557	CTLA-4 Protein, Rat, Recombinant (His)	Rat	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-03359	CTLA-4 Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-02411	CTLA-4 Protein, Canine, Recombinant (His)	Canine	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-00620	CTLA-4 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-03589	CTLA4 Protein, Cynomolgus/Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPJ-00107	CTLA-4 Protein, Human, Recombinant (Flag)	Human	Human Cells
	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence...
TMPY-02492	CTLA-4 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPJ-00420	CTLA-4 Protein, Mouse, Recombinant (Flag)	Mouse	Human Cells
	Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory pro...
TMPJ-00108	CTLA-4 Protein, Human, Recombinant (GST)	Human	Human Cells
	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence...
TMPJ-00635	CTLA-4 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPJ-00636	CTLA-4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPJ-00640	CTLA-4 Protein, Cavia porcellus, Recombinant (His)	Cavia porcellus	P. pastoris
	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPY-01674	CRTAM Protein, Human, Recombinant (His)	Human	HEK293
	Cytotoxic and regulatory T-cell molecule, also known as Class-I MHC-restricted T-cell-associated molecule and CRTAM, is a single-pass type I membrane protein which belongs to thenectin family.CRTAM contains oneIg-like...
TMPY-01721	CTLA-4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-04968	CTLA-4 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-06326	CTLA-4 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPJ-00429	CRTAM Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, pe...
TMPJ-00770	Granzyme B/GZMB Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPJ-01444	IL-17A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it ...
TMPJ-01422	CRTAM Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, pe...
TMPY-04948	CTLA-4 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-05002	CTLA-4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-04998	CTLA-4 Protein, Human, Recombinant (rFc)	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-06824	CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-05369	CTLA-4 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPJ-00655	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His）	Human	Human Cells
	Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TN...
TMPJ-00222	SLAMF7 Protein, Human, Recombinant (mFc)	Human	Human Cells
	SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c...
TMPJ-00221	SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c...
TMPJ-01442	SLAMF7 Protein, Rhesus macaque, Recombinant (His)	Rhesus Macaque	Human Cells
	SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c...
TMPJ-00216	IL-12B Protein, Human, Recombinant	Human	Human Cells
	Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, a...
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His)	Human	Yeast
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPY-04925	CD8 beta Protein, Human, Recombinant, Biotinylated	Human	HEK293
	CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-...
TMPY-00674	B7-1 Protein, Human, Recombinant	Human	HEK293
	The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B c...
TMPY-05074	NKG2A/CD159a Protein, Human, Recombinant (aa 94-233, His)	Human	HEK293
	NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this family are characteriz...
TMPY-03686	NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293
	NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this family are characteriz...
TMPY-01045	IL-12B Protein, Human, Recombinant (His)	Human	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-01714	IFN gamma Protein, Human, Recombinant	Human	CHO
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03516	IL-12B Protein, Mouse, Recombinant	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-02827	IFN gamma Protein, Rat, Recombinant (hFc)	Rat	HEK293
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03198	IL-12B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPY-01180	CD86 Protein, Human, Recombinant (His)	Human	HEK293
	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
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CTLA-4 Protein, Mouse, Recombinant (His)

TMPY-01604

Species: Mouse

Expression System: HEK293

Granzyme A/GZMA Protein, Human, Recombinant (His)

TMPY-05159

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant

TMPY-04824

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant (His)

TMPY-04348

Species: Human

Expression System: HEK293

IL-17 Protein, Mouse, Recombinant (His)

TMPJ-01172

Species: Mouse

Expression System: Human Cells

CTLA-4 Protein, Rat, Recombinant (His)

TMPY-02557

Species: Rat

Expression System: HEK293

CTLA-4 Protein, Cynomolgus, Rhesus, Recombinant (hFc)

TMPY-03359

Species: Cynomolgus,Rhesus

Expression System: HEK293

CTLA-4 Protein, Canine, Recombinant (His)

TMPY-02411

Species: Canine

Expression System: HEK293

CTLA-4 Protein, Canine, Recombinant (hFc)

TMPY-00620

Species: Canine

Expression System: HEK293

CTLA4 Protein, Cynomolgus/Rhesus, Recombinant (His)

TMPY-03589

Species: Cynomolgus,Rhesus

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant (Flag)

TMPJ-00107

Species: Human

Expression System: Human Cells

CTLA-4 Protein, Rat, Recombinant (hFc)

TMPY-02492

Species: Rat

Expression System: HEK293

Granzyme B/GZMB Protein, Human, Recombinant (His)

TMPY-00817

Species: Human

Expression System: HEK293

CTLA-4 Protein, Mouse, Recombinant (Flag)

TMPJ-00420

Species: Mouse

Expression System: Human Cells

CTLA-4 Protein, Human, Recombinant (GST)

TMPJ-00108

Species: Human

Expression System: Human Cells

CTLA-4 Protein, Cynomolgus, Recombinant (hFc)

TMPJ-00635

Species: Cynomolgus

Expression System: Human Cells

CTLA-4 Protein, Cynomolgus, Recombinant (His)

TMPJ-00636

Species: Cynomolgus

Expression System: Human Cells

CTLA-4 Protein, Cavia porcellus, Recombinant (His)

TMPJ-00640

Species: Cavia porcellus

Expression System: P. pastoris

CRTAM Protein, Human, Recombinant (His)

TMPY-01674

Species: Human

Expression System: HEK293

CTLA-4 Protein, Mouse, Recombinant (hFc)

TMPY-01721

Species: Mouse

Expression System: HEK293

CTLA-4 Protein, Mouse, Recombinant (His), Biotinylated

TMPY-04968

Species: Mouse

Expression System: HEK293

CTLA-4 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPY-06326

Species: Mouse

Expression System: HEK293

CRTAM Protein, Cynomolgus, Recombinant (hFc)

TMPJ-00429

Species: Cynomolgus

Expression System: Human Cells

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

TMPJ-00770

Species: Mouse

Expression System: Human Cells

IL-17A Protein, Cynomolgus, Recombinant (His)

TMPJ-01444

Species: Cynomolgus

Expression System: Human Cells

CRTAM Protein, Cynomolgus, Recombinant (His)

TMPJ-01422

Species: Cynomolgus

Expression System: Human Cells

CTLA-4 Protein, Human, Recombinant (His), Biotinylated

TMPY-04948

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant (hFc)

TMPY-05002

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant (rFc)

TMPY-04998

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-06824

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant (hFc), Biotinylated

TMPY-05369

Species: Human

Expression System: HEK293

TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His）

TMPJ-00655

Species: Human

Expression System: Human Cells

SLAMF7 Protein, Human, Recombinant (mFc)

TMPJ-00222

Species: Human

Expression System: Human Cells

SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00221

Species: Human

Expression System: Human Cells

SLAMF7 Protein, Rhesus macaque, Recombinant (His)

TMPJ-01442

Species: Rhesus Macaque

Expression System: Human Cells

IL-12B Protein, Human, Recombinant

TMPJ-00216

Species: Human

Expression System: Human Cells

Fas Ligand Protein, Human, Recombinant (His)

TMPY-03956

Species: Human

Expression System: Yeast

TNF alpha Protein, Rabbit, Recombinant

TMPJ-00779

Species: Rabbit

Expression System: E. coli

CD8 beta Protein, Human, Recombinant, Biotinylated

TMPY-04925

Species: Human

Expression System: HEK293

B7-1 Protein, Human, Recombinant

TMPY-00674

Species: Human

Expression System: HEK293

NKG2A/CD159a Protein, Human, Recombinant (aa 94-233, His)

TMPY-05074

Species: Human

Expression System: HEK293

NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc)

TMPY-03686

Species: Cynomolgus,Rhesus

Expression System: HEK293

IL-12B Protein, Human, Recombinant (His)

TMPY-01045

Species: Human

Expression System: HEK293

IFN gamma Protein, Human, Recombinant

TMPY-01714

Species: Human

Expression System: CHO

TNF beta Protein, Human, Recombinant

TMPY-02153

Species: Human

Expression System: E. coli

IFN gamma Protein, Human, Recombinant (E. coli)

TMPY-06983

Species: Human

Expression System: E. coli

IL-12B Protein, Mouse, Recombinant

TMPY-03516

Species: Mouse

Expression System: HEK293

IFN gamma Protein, Rat, Recombinant (hFc)

TMPY-02827

Species: Rat

Expression System: HEK293

IL-12B Protein, Mouse, Recombinant (His)

TMPY-03198

Species: Mouse

Expression System: HEK293

CD86 Protein, Human, Recombinant (His)

TMPY-01180

Species: Human

Expression System: HEK293

--------- More ---------

Cat No.	Product Name
L5500	Toxic Compound Library		277 compounds
	A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS);

Libraries

Toxic Compound Library

L5500

Compounds: 277